Fig. 3

hsa_miR-370-3p was a target of circ_0025033. A Circinteractome was used to predict the complementary sequence between hsa_miR-370-3p and circ_0025033. B Transfection efficiency of hsa_miR-370-3p in tumor cells. C and D Their binding was confirmed using dual-luciferase reporter assay in SKOV3 and A2780 cells cotransfected with WT-circ_0025033 or MUT-circ_0025033 and hsa_miR-370-3p or miR-NC. E and F Their interaction was examined using RNA pull-down. G qRT-PCR analysis of hsa_miR-370-3p in tumor tissue. H Their correlation was determined via Pearson’s correlation analysis in tumor samples. I hsa_miR-370-3p content in HOSEPiC, SKOV3, and A2780 cells. J circ_0025033 in cells transfected with pcD5-ciR or circ_0025033 was detected using qRT-PCR. K Effect of circ_0025033 deficiency or overexpression on hsa_miR-370-3p content was examined using qRT-PCR. ***P < 0.001, ****P < 0.0001