Fig. 2

The effects of circ_0086296 on ox-LDL-induced atherosclerotic phenotype in HUVECs. A The effects of circ_0086296 overexpression or sh-circ_0086296 were measured via qRT-PCR. B The viability of HUVECs infected with sh-circ_0086296 vector. **p < 0.001 versus the sham + shNC group. ^##p < 0.001 versus the oxLDL + shNC group. C The viability of HUVECs infected with circ_0086296 overexpression vector was determined via CCK-8 assay. **p < 0.001 versus the sham + shNC group. ^##p < 0.001 versus the oxLDL + shNC group. D The migration of HUVECs infected by circ_0086296 overexpression vector or sh-circ_0086296 vectors was determined via wound healing assay. Scale bar, 100 μm. **p < 0.001 versus the shNC group. ^##p < 0.001 versus the OE-NC group. E The migration of HUVECs transfected with circ_0086296 overexpression vector or sh-circ_0086296 vectors was determined via Transwell assay. Scale bar, 100 μm. **p < 0.001 versus the relative control group. ^##p < 0.001 versus the untreated group. F The angiogenic ability of HUVECs infected with circ_0086296 overexpression vector or sh-circ_0086296 vectors was measured via Matrigel assay. **p < 0.001 versus the relative control group. ^##p < 0.001 versus the untreated group