Skip to main content
Fig. 5 | Cellular & Molecular Biology Letters

Fig. 5

From: Pou3f1 mediates the effect of Nfatc3 on ulcerative colitis-associated colorectal cancer by regulating inflammation

Fig. 5

Pou3f1 knockdown protected against mucosal injury and colon tumorigenesis of UC-CRC mice. (A) The schematic diagram for animal model protocols. (B-C) The mRNA and protein levels of Pou3f1 in colons were measured by qPCR and Western blot. (D-E) The body weight and survival status of mice were recorded weekly. (F-G) The colon length was recorded. (H-J) Representative microscopic images of colon tumors. Total tumor number and the number of tumors with different diameters were counted. (K) Representative images of HE staining for colon tumors. The arrows indicated tumors. Data were from n = 6 mice per group for (B-D) and (F-K); n = 30 mice per group for (E). Values were mean ± SD. *, p <0.05; **, p < 0.01

Back to article page