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Fig. 1 | Cellular & Molecular Biology Letters

Fig. 1

From: Therapeutic overexpression of miR-92a-2-5p ameliorated cardiomyocyte oxidative stress injury in the development of diabetic cardiomyopathy

Fig. 1

Oxidative stress-responsive miRNAs were differentially expressed in DCM rat hearts. A Detection of random blood glucose levels in rats. n = 10 in each group. **P < 0.01. B Detection of blood glucose level in rats after insulin injection. n = 10 in each group. **P < 0.01. C Representative echocardiographic images of the rat hearts. D-H Evaluation of the mean values of LVIDs, LVAWs, LVPWs, EF, and FS in rats. n = 10 in each group. **P < 0.01. I Determination of the heart weight/body weight (HW/BW) ratio in rats. n = 10 in each group. **P < 0.01. J Representative images of H & E staining in rat heart tissues from control and T2DM groups. K Representative images of Masson’s staining in rat left ventricular tissues. Scale bar = 50 μm. L Screening of oxidative stress-responsive miRNAs in rat left ventricle tissues. n = 5 for each group. *P < 0.05, and ** P < 0.01 vs. control group. M Relative expression level of miR-92a-2-5p in rat left ventricular tissues. n = 10 in each group. ** P < 0.01

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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