Fig. 5

miR-92a-2-5p attenuated cardiomyocyte oxidative stress injury by targeting MKNK2. A Representative images of western blot for MKNK2 protein in cardiomyocytes infected with Ad-MKNK2 and/or Ad-miR-92a-2-5p under high glucose stimulation. B Integrated density analysis of immune bands using ImageJ software. β-actin was used as a loading control. n = 3 in each group. **P < 0.01. C Representative images of DCFH-DA staining in cardiomyocytes with adenovirus infection under high glucose stimulation. D-F Detection of ROS, GSH, and MDA levels in cardiomyocytes infected with adenovirus under high glucose stimulation. n = 5 in each group. **P < 0.01. G Representative images of TUNEL staining of cardiomyocytes infected with adenovirus under high glucose stimulation. The red arrows indicate the TUNEL-DAPI merge signals. H Detection of TUNEL-positive cardiomyocytes with adenovirus infection under high glucose stimulation. n = 5 in each group. **P < 0.01