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Fig. 5 | Cellular & Molecular Biology Letters

Fig. 5

From: Inhibition of CISD2 promotes ferroptosis through ferritinophagy-mediated ferritin turnover and regulation of p62–Keap1–NRF2 pathway

Fig. 5

NRF2 overexpression promotes the growth of xenografts via enhancing antioxidation. A The gross morphology of subcutaneous tumors in nude mice of each indicated group. B The curves of time-dependent tumor volume after the injection of Erastin. CE Detection of the GSH, MDA, and iron content, respectively, in tumor tissues from each group; protein concentration was used for calibration. P < 0.05 and P < 0.01 between the indicated groups

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