Fig. 5From: Inhibition of CISD2 promotes ferroptosis through ferritinophagy-mediated ferritin turnover and regulation of p62–Keap1–NRF2 pathwayNRF2 overexpression promotes the growth of xenografts via enhancing antioxidation. A The gross morphology of subcutaneous tumors in nude mice of each indicated group. B The curves of time-dependent tumor volume after the injection of Erastin. C–E Detection of the GSH, MDA, and iron content, respectively, in tumor tissues from each group; protein concentration was used for calibration. ★P < 0.05 and ★★P < 0.01 between the indicated groupsBack to article page