Fig. 2

The effect of SNHG16 on ESCC cell proliferation and migration in vitro. A The relative expression of SNHG16 in the normal human oesophageal epithelium cell line (HET-1A) and four ESCC cell lines (Eca109, KYSE30, KYSE140 and KYSE410). B Relative expression levels of SNHG16 in four ESCC cell lines transfected with sh-NC or sh-SNHG16 #1, #2 and #3 tested by qRT-PCR. C The effects of SNHG16 on ESCC cell proliferation ability, colony formation ability (D) and migration ability from Transwell assays (E) and wound healing assays (F). Error bars indicate the mean ± s.e.m. from three independent experiments (*P < 0.05, **P < 0.01, ***P < 0.001)