Fig. 6From: Anti-aging effect of β-carotene through regulating the KAT7-P15 signaling axis, inflammation and oxidative stress processThe effect of β-carotene on replicative aging in Ad-MSCs. A Analysis of aging of MSCs upon serial passage. n = 3 biological replicates. B The ratio of SA-β-gal-positive cells was down-regulated. n = 3 biological replicates. C The expression level of p16, p53, and p21 was down-regulated by β-carotene treatment. D β-carotene treatment increased the clonal expansion ability of MSCs. E H3K9me3 expression was increased by β-carotene treatment. F β-carotene treatment up-regulated HP1α and H3K9me3Back to article page