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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: Exosomal DNAJB11 promotes the development of pancreatic cancer by modulating the EGFR/MAPK pathway

Fig. 3

Exosomal DNAJB11 expression is associated with cell proliferation, invasion, and migration in pancreatic cancer cells. A Western blotting of DNAJB11 expression in pancreatic cancer cell lines and human normal pancreatic cell line. GAPDH was used as a control. Three independent experiments were performed. B PC cells were incubated with exosomes, and exosome markers CD63 and CD9 as well as exosomal DNAJB11 levels were measured using western blotting. Images of the wound healing assay (C), transwell (D), clone formation (E), and cellular apoptosis (F), and corresponding statistical analysis, respectively. After incubation with AsPC-1-exoor shDNAJB11-exo for 72 h, PC cell line migration, invasion, proliferation, and apoptosis were recorded (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, one-way ANOVA). AsPC-1 and Capan-2 cell lines were the control group

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