E2F1 promotes cell cycle progression by stabilizing spindle fiber in colorectal cancer cells

Table 1 Association of the expression of E2F1, stathmin1, and TACC3 with clinicopathological features in CRC

	Cases	E2F1 expression			STMN1 expression			TACC3 expression
		Low	High	P-value	Low	High	P-value	Low	High	P-value
		Cases	Cases	P-value	Cases	Cases	P-value	Cases	Cases	P-value
	231	114	117		117	114		129	102
Tumor location
Colon	97	46	51	0.8596	51	46	0.1869	55	42	0.7685
Rectum	134	68	66	0.8596	66	68	0.1869	74	60	0.7685
Gender
Male	124	55	69	0.2213	65	59	0.4271	66	58	0.0915
Female	107	59	48	0.2213	52	55	0.4271	63	44	0.0915
Age
≤ 65	93	42	51	0.5457	48	45	0.9476	52	41	0.9877
> 65	138	72	66	0.5457	69	69	0.9476	77	61	0.9877
Differentiation status
Well	50	23	27	0.1206	27	23	0.7617	28	22	0.7723
Moderate	154	84	70		79	75		88	66
Poor	27	7	20		11	16		13	14
Tumor size
< 5 cm	110	56	54	0.0729	63	47	0.0208*	70	40	0.0247*
≥ 5 cm	121	58	63	0.0729	54	67	0.0208*	59	62	0.0247*
LNM
N0	130	72	58	0.0214*	76	54	0.0040*	79	51	0.0108*
N1	73	34	39		32	41		37	36
N2	28	8	20		9	19		13	15
TNM
I	35	19	16	0.0030*	21	14	0.0014*	16	19	0.0001*
II	88	46	42		47	41		58	30
III	89	45	44		46	43		51	38
IV	19	4	15		3	16		4	15
Distant metastasis
M0	212	110	102	0.0002*	114	98	0.0001*	125	87	< 0.0001*
M1	19	4	15	0.0002*	3	16	0.0001*	4	15	< 0.0001*

ISSN: 1689-1392