Table 2 Multivariate and univariate analysis of prognostic factors for OS
From: E2F1 promotes cell cycle progression by stabilizing spindle fiber in colorectal cancer cells
Variable | Multivariate | Univariate | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | P-value | HR | 95% CI | P-value | |
Tumor location (colon versus rectum) | 0.984 | 0.725–1.333 | 0.9130 | 1.058 | 0.770–1.453 | 0.7280 |
Gender (male versus female) | 0.875 | 0.646–1.174 | 0.3728 | 0.960 | 0.701–1.314 | 0.7987 |
Age (≤ 65 years versus > 65 years) | 1.439 | 1.086–1.973 | 0.0154 | 1.374 | 0.981–1.923 | 0.0642 |
Tumor size (< 5.0 cm versus ≥ 5.0 cm) | 1.238 | 0.926–1.680 | 0.1540 | 1.108 | 0.809–1.517 | 0.5231 |
LNM (N0 versus N1/2) | 0.999 | 0.740–1.348 | 0.9929 | 0.847 | 0.606–1.185 | 0.3331 |
Differentiation (well and moderate versus poorly) | 1.667 | 1.157–3.184 | 0.0133 | 1.333 | 0.833–2.134 | 0.2306 |
Distant metastasis (no versus yes) | 2.046 | 1.419–5.531 | 0.0035 | 1.737 | 1.008–2.981 | 0.0466 |
E2F1 expression (low versus high) | 1.642 | 1.255–2.290 | 0.0008 | 1.332 | 0.892–1.989 | 0.1608 |
STMN1 expression (low versus high) | 1.877 | 1.496–2.754 | < 0.0001 | 1.707 | 1.165–2.502 | 0.0061 |
TACC3 expression (low versus high) | 1.373 | 1.041–1.924 | 0.0315 | 0.899 | 0.620–1.302 | 0.5727 |