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Fig. 5 | Cellular & Molecular Biology Letters

Fig. 5

From: Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway

Fig. 5

Hsa-miR-7-5p is involved in the JNK-mediated atypical WNT signalling pathway and significantly inhibits breast cancer metastasis. A Western blot analysis of E-cadherin and N-cadherin protein expression levels after treatment of MDA-MB-231 cells with blank controls or miR-7-5p mimics, inhibitors and their negative controls. B Western blot analysis of p-JNK, p-c-Jun and ZEB1 protein expression levels after treatment of MDA-MB-231 cells with blank control or miR-7-5p mimics, inhibitors and their negative controls. Data are presented as mean ± SD (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001

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