Fig. 2
From: Targeting UBR5 in hepatocellular carcinoma cells and precise treatment via echinacoside nanodelivery
UBR5 knockdown induces cell apoptosis and reduces OCR and ECAR levels in HepG2 cells. A GSEA showed that UBR5 expression is associated with glycolysis and β-catenin signaling. B, C UBR5 expression, D cell apoptosis, E OCR, F ECAR, and G, H LDHA, PKM2, Survivin, C-myc, and β-catenin expression in HepG2 cells transduced with indicated plasmids. ***P < 0.001 compared with shNC