Targeting UBR5 in hepatocellular carcinoma cells and precise treatment via echinacoside nanodelivery

Table 1 Correlation of the expression of UBR5 with clinicopathologic features of patients with HCC

Clinicopathological parameter	UBR5		P value
Clinicopathological parameter	Low group, number of patients	High group, number of patients	P value
Age, years
≤ 52	39	84	0.5329
> 52	45	82	0.5329
Sex
Female	45	74	0.1787
Male	39	92	0.1787
Size (cm)
≤ 5	51	70	0.0056
> 5	33	96	0.0056
AJCC stage
I	27	26	0.0097
II	24	59
III	20	63
IV	13	18
Histological grade
G1	16	22	0.0013
G2	46	58
G3	20	71
G4	2	15
Differentiation
Low	25	33	0.0851
Moderate	45	88
High	14	45
Lung metastasis
Yes	33	90	0.0257
No	51	76	0.0257
HBV infection
Yes	42	93	0.3667
No	42	73

HBV hepatitis B virus. Differences between groups were determined by chi-square test

ISSN: 1689-1392