Fig. 6
From: tRF-3013b inhibits gallbladder cancer proliferation by targeting TPRG1L
Overexpression of TPRG1L rescued the inhibitory effects of tRF-3013b. A CCK8 assay and B colony formation were performed to evaluated cell proliferation capacity after cotransfection of NOZ and GBC-SD with NC or tRF-3013b mimic and vector or TPRG1L. C Relative protein expression of TPRG1L, p65, p50, c-myc, CDK2, and p-CDK2 after cotransfection of NOZ and GBC-SD with NC or tRF-3013b mimic and vector or TPRG1L. D Cell-cycle assay was evaluated after cotransfection of NOZ and GBC-SD with NC or tRF-3013b mimic and vector or TPRG1L. E Schematic depiction of the function and potential mechanism of tRF-3013b in GBC. *P < 0.05, **P < 0.01, ***P < 0.001