Fig. 2

Structure and interactions of LSSL. A A representative negative stain (left) and cryo-electron microscopy (EM) (right) raw micrograph of LSSL. B Two-dimensional class averages of LSSL. C Surface representation of LSSL, viewed down the five-fold axis and colored by the radius (left). Cross-sectional view showing the internal features. LSSL assembled as icosahedral capsids, composed of incomplete symmetrical structure of five tetramers. Side view (D) and top view (E) of a tetramer structure. The interactions between tetramers in three orientations are shown in E. Orange, violet, and green indicate chain A, chain B, and chain C, respectively. The boxes indicate the magnified views of the interactions, and the representative residues are shown