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Fig. 1 | Cellular & Molecular Biology Letters

Fig. 1

From: Targeting uridine–cytidine kinase 2 induced cell cycle arrest through dual mechanism and could improve the immune response of hepatocellular carcinoma

Fig. 1

UCK2 was upregulated in HCC and involved in tumour stemness. A Volcano plot for different expression genes between tumour and adjacent tissues. B, C Lasso–Cox regression analysis filtered genes significantly associated with the prognosis of HCC. D Integrative molecular database of HCC (HCCDB) database was used to examine the role of TYMS, UCK2 and DTYMK in HCC. E The expression of UCK2 in different stage during HCC development, data derived from GEO6764. F GSEA analysis revealed the signalling pathways related to UCK2. G Correlation of UCK2 and stemness features. H 3D sphere formation for the indicated cell lines, *p < 0.05; **p < 0.01; ***p < 0.001

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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