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Fig. 2 | Cellular & Molecular Biology Letters

Fig. 2

From: Three-dimensional genome landscape comprehensively reveals patterns of spatial gene regulation in papillary and anaplastic thyroid cancers: a study using representative cell lines for each cancer type

Fig. 2

A, B Spatial proximity of co-mutated gene pairs. Bar plots of the TAD counts A without or (B) with CoMut hotspots over each chromosome in ATC (8305c), PTC (BCPAP), and PTC (TPC-1) cells. C–F Spatial proximities of co-mutated gene clusters in TAD based on Hi-C data. CoMut hotspots mutation gene pairs were found in ATC-specific TAD structures

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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