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Fig. 7 | Cellular & Molecular Biology Letters

Fig. 7

From: Three-dimensional genome landscape comprehensively reveals patterns of spatial gene regulation in papillary and anaplastic thyroid cancers: a study using representative cell lines for each cancer type

Fig. 7

A–G Density of distance between regulatory features and changed TADs in ATC cells. Various factors and regulatory and epigenetic markers around changed TADs in ATC compared with normal cells are shown in A–F, in which different TAD change modes, including de novo, loss, and shifted, were compared; G The significance of differences between two TAD change modes (de novo versus shifted, de novo versus loss, and loss versus shifted) for epigenetic markers are visualized using heat maps. H–N Density of distance between regulatory features and changed TAD in PTC cells. Various factors and regulatory and epigenetic markers around changed TADs in PTC compared with normal cell line are shown in H–M, in which different TAD change modes, including de novo, loss, and shifted are compared. N The significance of differences between two TAD change modes (de novo versus shifted, de novo versus loss, and loss versus shifted) for epigenetic markers are visualized using heat maps

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