TY - JOUR AU - Mezzetti, M. AU - Panigalli, T. AU - Giuliani, L. AU - Raveglia, F. AU - Giudice, F. L. AU - Meda, S. PY - 2002 DA - 2002// TI - Personal experience in lung cancer sleeve lobectomy and sleeve pneumonectomy JO - Ann. Thorac. Surg. VL - 73 UR - https://doi.org/10.1016/S0003-4975(02)03524-5 DO - 10.1016/S0003-4975(02)03524-5 ID - Mezzetti2002 ER - TY - JOUR AU - Greenlee, R. T. AU - Murray, T. AU - Bolden, S. AU - Wingo, P. A. PY - 2000 DA - 2000// TI - Cancer statistics, 2000 JO - CA Cancer J. Clin. VL - 50 ID - Greenlee2000 ER - TY - JOUR AU - Jiang, Y. AU - Rom, W. N. AU - Yie, T. A. AU - Chi, C. X. AU - Tchou-Wong, K. M. PY - 1999 DA - 1999// TI - Induction of tumor suppression and glandular differentiation of A549 lung carcinoma cells by dominant-negative IGF-I receptor JO - Oncogene VL - 18 UR - https://doi.org/10.1038/sj.onc.1202984 DO - 10.1038/sj.onc.1202984 ID - Jiang1999 ER - TY - JOUR AU - Min, Y. AU - Adachi, Y. AU - Yamamotom, H. AU - Ito, H. AU - Itoh, F. AU - Lee, C. T. AU - Nadaf, S. AU - Carbone, D. P. AU - Imai, K. PY - 2003 DA - 2003// TI - Genetic blockade of the insulin-like growth factor-I receptor: a promising strategy for human pancreatic cancer JO - Cancer Res. VL - 64 ID - Min2003 ER - TY - JOUR AU - Zhang, D. AU - Bar-Eli, M. AU - Meloche, S. AU - Brodt, P. PY - 2004 DA - 2004// TI - Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals JO - J. Biol. Chem. VL - 279 UR - https://doi.org/10.1074/jbc.M313145200 DO - 10.1074/jbc.M313145200 ID - Zhang2004 ER - TY - JOUR AU - LeRoith, D. AU - Werner, H. AU - Beitner-Johnson, D. AU - Roberts, C. T. PY - 1995 DA - 1995// TI - Molecular and cellular aspects of the insulin-like growth factor I receptor JO - Endocr. Rev. VL - 16 UR - https://doi.org/10.1210/er.16.2.143 DO - 10.1210/er.16.2.143 ID - LeRoith1995 ER - TY - JOUR AU - Nakanishi, Y. AU - Mulshine, J. L. AU - Kasprzyk, P. G. AU - Natale, R. B. AU - Maneckjee, R. AU - Avis, I. AU - Treston, A. M. AU - Gazdar, A. F. AU - Minna, J. D. AU - Cuttitta, F. PY - 1988 DA - 1988// TI - Insulin-like growth factor-I can mediate autocrine proliferation of human small cell lung cancer cell lines in vitro JO - J. Clin. Invest. VL - 82 ID - Nakanishi1988 ER - TY - JOUR AU - Kaleko, M. AU - Rutter, W. J. AU - Miller, A. D. PY - 1990 DA - 1990// TI - Overexpression of the human insulin-like growth factor I receptor promotes ligand-dependent neoplastic transformation JO - Mol. Cell. Biol. VL - 10 ID - Kaleko1990 ER - TY - JOUR AU - Remacle-Bonnet, M. M. AU - Garrouste, F. L. AU - Heller, S. AU - Andre, F. AU - Marvaldi, J. L. AU - Pommier, G. J. PY - 2000 DA - 2000// TI - Insulin-like growth factor-I protects colon cancer cells from death factor-induced apoptosis by potentiating tumor necrosis factor alpha-induced mitogen-activated protein kinase and nuclear factor kappaB signaling pathways JO - Cancer Res. VL - 60 ID - Remacle-Bonnet2000 ER - TY - JOUR AU - Singh, P. PY - 2000 DA - 2000// TI - Insulin-like growth factor system in growth, development and carcinogenesis JO - J. Clin. Lig. Assay VL - 23 ID - Singh2000 ER - TY - JOUR AU - Scotlandi, K. AU - Maini, C. AU - Manara, M. C. AU - Benini, S. AU - Serra, M. AU - Cerisano, V. AU - Strammiello, R. AU - Baldini, N. AU - Lollini, P. L. AU - Nanni, P. AU - Nicoletti, G. AU - Picci, P. PY - 2002 DA - 2002// TI - Effectiveness of insulin-like growth factor I receptor antisense strategy against Ewing’s sarcoma cells JO - Cancer Gene Ther. VL - 9 UR - https://doi.org/10.1038/sj.cgt.7700442 DO - 10.1038/sj.cgt.7700442 ID - Scotlandi2002 ER - TY - JOUR AU - Turner, B. C. AU - Haffty, B. G. AU - Narayanan, L. AU - Yuan, J. AU - Havre, P. A. AU - Gumbs, A. A. AU - Kaplan, L. AU - Burgaud, J. L. AU - Carter, D. AU - Baserga, R. AU - Glazer, P. M. PY - 1997 DA - 1997// TI - Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation JO - Cancer Res. VL - 57 ID - Turner1997 ER - TY - JOUR AU - Wu, Y. AU - Tewari, M. AU - Cui, S. AU - Rubin, R. PY - 1996 DA - 1996// TI - Activation of the insulin-like growth factor-I receptor inhibits tumor necrosis factor-induced cell death JO - J. Cell Physiol. VL - 168 UR - https://doi.org/3.0.CO;2-K DO - 3.0.CO;2-K ID - Wu1996 ER - TY - JOUR AU - Grimberg, A. AU - Cohen, P. PY - 1999 DA - 1999// TI - Growth hormone and prostate cancer: guilty by association? JO - J. Endocrinol. Invest. VL - 22 ID - Grimberg1999 ER - TY - JOUR AU - Ma, J. AU - Pollak, M. AU - Giovannucci, E. AU - Chan, J. M. AU - Tao, Y. AU - Hennekens, C. AU - Stampfer, M. J. PY - 2000 DA - 2000// TI - A prospective study of plasma levels of insulin-like growth factor I (IGF-I) and IGF-binding protein-3, and colorectal cancer risk among men JO - Growth Horm. IGF Res. VL - 10 UR - https://doi.org/10.1016/S1096-6374(00)90013-3 DO - 10.1016/S1096-6374(00)90013-3 ID - Ma2000 ER - TY - JOUR AU - Yu, H. AU - Spitz, M. R. AU - Mistry, J. AU - Gu, J. AU - Hong, W. K. AU - Wu, X. PY - 1999 DA - 1999// TI - Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis JO - J. Natl. Cancer Inst. VL - 91 UR - https://doi.org/10.1093/jnci/91.2.151 DO - 10.1093/jnci/91.2.151 ID - Yu1999 ER - TY - JOUR AU - Maile, L. A. AU - Imai, Y. AU - Clarke, J. B. AU - Clemmons, D. R. PY - 2002 DA - 2002// TI - Insulin-like growth factor I increases alpha Vbeta 3 affinity by increasing the amount of integrin-associated protein that is associated with non-raft domains of the cellular membrane JO - J. Biol. Chem. VL - 277 UR - https://doi.org/10.1074/jbc.M108380200 DO - 10.1074/jbc.M108380200 ID - Maile2002 ER - TY - JOUR AU - Playford, M. P. AU - Bicknell, D. AU - Bodmer, W. F. AU - Macaulay, V. M. PY - 2000 DA - 2000// TI - Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin JO - Proc. Natl. Acad. Sci. USA. VL - 97 UR - https://doi.org/10.1073/pnas.210394297 DO - 10.1073/pnas.210394297 ID - Playford2000 ER - TY - JOUR AU - Sachdev, D. AU - Hartell, J. S. AU - Lee, A. V. AU - Zhang, X. AU - Yee, D. PY - 2004 DA - 2004// TI - A dominant negative type I insulin-like growth factor receptor inhibits metastasis of human cancer cells JO - J. Biol. Chem. VL - 279 UR - https://doi.org/10.1074/jbc.M305403200 DO - 10.1074/jbc.M305403200 ID - Sachdev2004 ER - TY - JOUR AU - Cockett, M. I. AU - Murphy, G. AU - Birch, M. L. AU - O’Connell, J. P. AU - Crabbe, T. AU - Millican, A. T. AU - Hart, I. R. AU - Docherty, A. J. PY - 1998 DA - 1998// TI - Matrix metalloproteinases and metastatic cancer JO - Biochem. Soc. Symp. VL - 63 ID - Cockett1998 ER - TY - JOUR AU - Kleiner, D. E. AU - Stetler-Stevenson, W. G. PY - 1999 DA - 1999// TI - Matrix metalloproteinases and metastasis JO - Cancer Chemother. Pharmacol. VL - 43 UR - https://doi.org/10.1007/s002800051097 DO - 10.1007/s002800051097 ID - Kleiner1999 ER - TY - JOUR AU - Ohbayashi, H. PY - 2002 DA - 2002// TI - Matrix metalloproteinases in lung diseases JO - Curr. Protein Pept. Sci. VL - 3 UR - https://doi.org/10.2174/1389203023380549 DO - 10.2174/1389203023380549 ID - Ohbayashi2002 ER - TY - JOUR AU - Maloney, E. K. AU - McLaughlin, J. L. AU - Dagdigian, N. E. AU - Garrett, L. M. AU - Connors, K. M. AU - Zhou, X. M. AU - Blattler, W. A. AU - Chittenden, T. AU - Singh, R. PY - 2003 DA - 2003// TI - An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation JO - Cancer Res. VL - 63 ID - Maloney2003 ER - TY - JOUR AU - Chernicky, C. L. AU - Yi, L. AU - Tan, H. AU - Gan, S. U. AU - Ilan, J. PY - 2000 DA - 2000// TI - Treatment of human breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor inhibits cell growth, suppresses tumorigenesis, alters the metastatic potential, and prolongs survival in vivo JO - Cancer Gene Ther. VL - 7 UR - https://doi.org/10.1038/sj.cgt.7700126 DO - 10.1038/sj.cgt.7700126 ID - Chernicky2000 ER - TY - JOUR AU - Dykxhoorn, D. M. AU - Novina, C. D. AU - Sharp, P. A. PY - 2003 DA - 2003// TI - Killing the messenger: short RNAs that silence gene expression JO - Nat. Rev. Mol. Cell Biol. VL - 4 UR - https://doi.org/10.1038/nrm1129 DO - 10.1038/nrm1129 ID - Dykxhoorn2003 ER - TY - JOUR AU - Bohula, E. A. AU - Salisbury, A. J. AU - Sohail, M. AU - Playford, M. P. AU - Riedemann, J. AU - Southern, E. M. AU - Macaulay, V. M. PY - 2003 DA - 2003// TI - The efficacy of small interfering RNAs targeted to the type 1 insulin-like growth factor receptor (IGF1R) is influenced by secondary structure in the IGF1R transcript JO - J. Biol. Chem. VL - 278 UR - https://doi.org/10.1074/jbc.M300714200 DO - 10.1074/jbc.M300714200 ID - Bohula2003 ER - TY - JOUR AU - Lee, C. T. AU - Park, K. H. AU - Adachi, Y. AU - Seol, J. Y. AU - Yoo, C. G. AU - Kim, Y. W. AU - Han, S. K. AU - Shim, Y. S. AU - Coffee, K. AU - Dikov, M. M. AU - Carbone, D. P. PY - 2003 DA - 2003// TI - Recombinant adenoviruses expressing dominant negative insulin-like growth factor-I receptor demonstrate anti-tumor effects on lung cancer JO - Cancer Gene Ther. VL - 10 UR - https://doi.org/10.1038/sj.cgt.7700524 DO - 10.1038/sj.cgt.7700524 ID - Lee2003 ER - TY - JOUR AU - Zhang, H. AU - Ma, G. AU - Dong, M. AU - Zhao, M. AU - Shen, X. AU - Ma, Z. AU - Guo, K. PY - 2006 DA - 2006// TI - Epidermal growth factor promotes invasiveness of pancreatic cancer cells through NF-kappaB-mediated proteinase productions JO - Pancreas VL - 32 UR - https://doi.org/10.1097/01.mpa.0000191644.94301.be DO - 10.1097/01.mpa.0000191644.94301.be ID - Zhang2006 ER - TY - JOUR AU - Scotlandi, K. AU - Benini, S. AU - Nanni, P. AU - Lollini, P. L. AU - Nicoletti, G. AU - Landuzzi, L. AU - Serra, M. AU - Manara, M. C. AU - Picci, P. AU - Baldini, N. PY - 1998 DA - 1998// TI - Blockage of insulin-like growth factor-I receptor inhibits the growth of Ewing’s sarcoma in athymic mice JO - Cancer Res. VL - 58 ID - Scotlandi1998 ER - TY - JOUR AU - Lee, C. T. AU - Wu, S. AU - Gabrilovich, D. AU - Chen, H. AU - Nadaf-Rahrov, S. AU - Ciernik, I. F. AU - Carbone, D. P. PY - 1996 DA - 1996// TI - Anti-tumor effects of an adenovirus expressing antisense insulin-like growth factor I receptor on human lung cancer cell lines JO - Cancer Res. VL - 56 ID - Lee1996 ER - TY - JOUR AU - Dunn, S. E. AU - Ehrlich, M. AU - Sharp, N. J. AU - Reiss, K. AU - Solomon, G. AU - Hawkins, R. AU - Baserga, R. AU - Barrett, J. C. PY - 1998 DA - 1998// TI - A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer JO - Cancer Res. VL - 58 ID - Dunn1998 ER - TY - JOUR AU - Zamore, P. D. PY - 2001 DA - 2001// TI - RNA interference: listening to the sound of silence JO - Nature Structural Biology VL - 8 UR - https://doi.org/10.1038/nsb0901-746 DO - 10.1038/nsb0901-746 ID - Zamore2001 ER - TY - JOUR AU - Miyagishi, M. AU - Taira, K. PY - 2002 DA - 2002// TI - U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells JO - Nature Biotechnology VL - 20 UR - https://doi.org/10.1038/nbt0502-497 DO - 10.1038/nbt0502-497 ID - Miyagishi2002 ER - TY - JOUR AU - Dong, A. Q. AU - Kong, M. J. AU - Ma, Z. Y. AU - Qian, J. F. AU - Xu, X. H. PY - 2007 DA - 2007// TI - Down-regulation of IGF-IR using small, interfering, hairpin RNA (siRNA) inhibits growth of human lung cancer cell line A549 in vitro and in nude mice JO - Cell Biol. Int. VL - 31 UR - https://doi.org/10.1016/j.cellbi.2006.11.017 DO - 10.1016/j.cellbi.2006.11.017 ID - Dong2007 ER - TY - JOUR AU - Dunn, S. E. AU - Torres, J. V. AU - Oh, J. S. AU - Cykert, D. M. AU - Barrett, J. C. PY - 2001 DA - 2001// TI - Upregulation of urokinase-type plasminogen activator by insulin-like growth factor-I depends upon phosphatidylinositol-3 kinase and mitogen-activated protein kinase kinase JO - Cancer Res. VL - 61 ID - Dunn2001 ER - TY - JOUR AU - Salatino, M. AU - Schillaci, R. AU - Proietti, C. J. AU - Carnevale, R. AU - Frahm, I. AU - Molinolo, A. A. AU - Iribarren, A. AU - Charreau, E. H. AU - Elizalde, P. V. PY - 2004 DA - 2004// TI - Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulinlike growth factor receptor mRNA involves inactivation of ErbBs, PI 3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone receptor activity JO - Oncogene VL - 23 UR - https://doi.org/10.1038/sj.onc.1207659 DO - 10.1038/sj.onc.1207659 ID - Salatino2004 ER - TY - JOUR AU - Tai, Y. T. AU - Podar, K. AU - Catley, L. AU - Tseng, Y. H. AU - Akiyama, M. AU - Shringarpure, R. AU - Burger, R. AU - Hideshima, T. AU - Chauhan, D. AU - Mitsiades, N. AU - Richardson, P. AU - Munshi, N. C. AU - Kahn, C. R. AU - Mitsiades, C. AU - Anderson, K. C. PY - 2003 DA - 2003// TI - Insulin-like growth factor-1 induces adhesion and migration in human multiple myeloma cells via activation of beta1-integrin and phosphatidylinositol 3′-kinase/AKT signaling JO - Cancer Res. VL - 63 ID - Tai2003 ER - TY - JOUR AU - Muller, D. AU - Breathnach, R. AU - Engelmann, A. AU - Millon, R. AU - Bronner, G. AU - Flesch, H. AU - Dumont, P. AU - Eber, M. AU - Abecassis, J. PY - 1991 DA - 1991// TI - Expression of collagenaserelated metalloproteinase genes in human lung or head and neck tumours JO - Int. J. Cancer. VL - 48 UR - https://doi.org/10.1002/ijc.2910480412 DO - 10.1002/ijc.2910480412 ID - Muller1991 ER - TY - JOUR AU - Kanayama, H. AU - Yokota, K. AU - Kurokawa, Y. AU - Murakami, Y. AU - Nishitani, M. AU - Kagawa, S. PY - 1998 DA - 1998// TI - Prognostic values of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in bladder cancer JO - Cancer VL - 82 UR - https://doi.org/3.0.CO;2-4 DO - 3.0.CO;2-4 ID - Kanayama1998 ER - TY - JOUR AU - Schmitt, M. AU - Harbeck, N. AU - Thomssen, C. AU - Wilhelm, O. AU - Magdolen, V. AU - Reuning, U. AU - Ulm, K. AU - Hofler, H. AU - Janicke, F. AU - Graeff, H. PY - 1997 DA - 1997// TI - Clinical impact of the plasminogen activation system in tumor invasion and metastasis: prognostic relevance and target for therapy JO - Thromb. Haemost. VL - 78 UR - https://doi.org/10.1159/000134673 DO - 10.1159/000134673 ID - Schmitt1997 ER - TY - JOUR AU - Pulukuri, S. M. AU - Gondi, C. S. AU - Lakka, S. S. AU - Jutla, A. AU - Estes, N. AU - Gujrati, M. AU - Rao, J. S. PY - 2005 DA - 2005// TI - RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo JO - J. Biol. Chem. VL - 280 UR - https://doi.org/10.1074/jbc.M503111200 DO - 10.1074/jbc.M503111200 ID - Pulukuri2005 ER - TY - JOUR AU - Kondraganti, S. AU - Mohanam, S. AU - Chintala, S. K. AU - Kin, Y. AU - Jasti, S. L. AU - Nirmala, C. AU - Lakka, S. S. AU - Adachi, Y. AU - Kyritsis, A. P. AU - Ali-Osman, F. AU - Sawaya, R. AU - Fuller, G. N. AU - Rao, J. S. PY - 2000 DA - 2000// TI - Selective suppression of matrix metalloproteinase-9 in human glioblastoma cells by antisense gene transfer impairs glioblastoma cell invasion JO - Cancer Res. VL - 60 ID - Kondraganti2000 ER - TY - JOUR AU - Grzmil, M. AU - Hemmerlein, B. AU - Thelen, P. AU - Schweyer, S. AU - Burfeind, P. PY - 2004 DA - 2004// TI - Blockade of the type I IGF receptor expression in human prostate cancer cells inhibits proliferation and invasion, up-regulates IGF binding protein-3, and suppresses MMP-2 expression JO - J. Pathol. VL - 202 UR - https://doi.org/10.1002/path.1492 DO - 10.1002/path.1492 ID - Grzmil2004 ER -