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Cellular & Molecular Biology Letters


Archival content

Cellular & Molecular Biology Letters was founded in 1996 and transferred to BioMed Central in 2016. Previously, its publishers were Walter De Gruyter in 2015 (content available from De Gruyter's archive), and Springer from 2006–2014 (content available from BMC web page). Articles published between 1996 and 2005 can be found at, CMBL home page, the Volume List tab. To request free electronic versions of these articles, please contact

Thematic Series

Invited Papers

The papers in this collection were specially invited by the editors and represent work by leading researchers in their fields, as well the authors of the most cited papers from the previous issues of our journal (CMBL).

All Articles

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  1. Content type: Review

    Human milk is a complex fluid that has developed to satisfy the nutritional requirements of infants. In addition to proteins, lipids, carbohydrates and other biologically active components, breast milk contain...

    Authors: Malgorzata Witkowska-Zimny and Ewa Kaminska-El-Hassan

    Citation: Cellular & Molecular Biology Letters 2017 22:11

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  2. Content type: Short report

    H19 is a well-characterized Long noncoding RNA (lncRNA) that has been proven to promote myoblast differentiation in humans and mice. However, its mechanism of action is still not fully interpreted.

    Authors: Xiaochun Xu, Shengyue Ji, Weili Li, Bao Yi, Hengxin Li, Hongfu Zhang and Wenping Ma

    Citation: Cellular & Molecular Biology Letters 2017 22:10

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  3. Content type: Short report

    The gene that encodes tumor protein p53, Tp53, is mutated or silenced in most human cancers and is recognized as one of the most important cancer drivers. Homozygotic Tp53 knockout mice, which develop lethal canc...

    Authors: Damian Strzemecki, Magdalena Guzowska and Paweł Grieb

    Citation: Cellular & Molecular Biology Letters 2017 22:9

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  4. Content type: Review

    Squamous cell carcinoma (SCC) is the most common cancer worldwide. The treatment of locally advanced disease generally requires various combinations of radiotherapy, surgery, and systemic therapy. Despite aggr...

    Authors: Zakir Khan, Abdul Arif Khan, Hariom Yadav, Godavarthi B. K. S. Prasad and Prakash Singh Bisen

    Citation: Cellular & Molecular Biology Letters 2017 22:8

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  5. Content type: Short Report

    Pseudoxanthoma elasticum (PXE) is characterized by progressive ectopic mineralization of elastic fibers in dermal, ocular and vascular tissues. No effective treatment exists. It is caused by inactivating mutat...

    Authors: Rocchina Miglionico, Angela Ostuni, Maria Francesca Armentano, Luigi Milella, Elvira Crescenzi, Monica Carmosino and Faustino Bisaccia

    Citation: Cellular & Molecular Biology Letters 2017 22:7

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  6. Content type: Short report

    Although the 3T3-L1 preadipocyte cell line represents an informative model for in vitro adipogenesis research, primary cultured cells are often needed to understand particular human or animal metabolic phenotypes...

    Authors: Yong Pu and Almudena Veiga-Lopez

    Citation: Cellular & Molecular Biology Letters 2017 22:6

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  7. Content type: Research

    Human Tenon’s fibroblasts (HTFs) play a crucial role in wound healing. They cause postoperative scarring of the filtering bleb and are thus responsible for trabeculectomy failure. This study aimed to find an e...

    Authors: Agata Przekora, Tomasz Zarnowski and Grazyna Ginalska

    Citation: Cellular & Molecular Biology Letters 2017 22:5

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  8. Content type: Mini review

    Neuron-glial antigen 2 (NG2), also known as chondroitin sulphate proteoglycan 4 (CSPG4), is a surface type I transmembrane core proteoglycan that is crucially involved in cell survival, migration and angiogene...

    Authors: Emmanuel Ampofo, Beate M. Schmitt, Michael D. Menger and Matthias W. Laschke

    Citation: Cellular & Molecular Biology Letters 2017 22:4

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  9. Content type: Research

    Atherosclerosis is a chronically inflammatory disease and one of the leading causes of deaths worldwide. Endothelial cell apoptosis plays a crucial role in its development. Several microRNAs (miRNAs) are repor...

    Authors: Ying Li, Chunyan Yang, Lili Zhang and Ping Yang

    Citation: Cellular & Molecular Biology Letters 2017 22:3

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  10. Content type: Short report

    PU box-binding protein (PU.1) is a master gene of hematopoietic lineage and an important specific transcription factor in osteoclast lineage. There is proof of its expression in adipose tissue, and it is known...

    Authors: ChongMei Ruan, Xiu Li, JunJie Hu, Yong Zhang and XingXu Zhao

    Citation: Cellular & Molecular Biology Letters 2017 22:2

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  11. Content type: Research

    The harmful side effects of electroporation to cells due to local changes in pH, the appearance of toxic electrode products, temperature increase, and the heterogeneity of the electric field acting on cells in...

    Authors: Maciej Grys, Zbigniew Madeja and Włodzimierz Korohoda

    Citation: Cellular & Molecular Biology Letters 2017 22:1

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  12. Content type: Mini review

    The ubiquitin–proteasome system (UPS) and autophagy are two distinct and interacting proteolytic systems. They play critical roles in cell survival under normal conditions and during stress. An increasing body...

    Authors: Wei Jing Liu, Lin Ye, Wei Fang Huang, Lin Jie Guo, Zi Gan Xu, Hong Luan Wu, Chen Yang and Hua Feng Liu

    Citation: Cellular & Molecular Biology Letters 2016 21:29

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  13. Content type: Short report

    Immunoglobulin G (IgG) has been implicated in the progression of various cancers. This study explored the role of IgG in the proliferation, apoptosis, cell cycle and in vitro invasive properties of LNCaP prost...

    Authors: Yawen Xu, Binshen Chen, Shaobo Zheng, Yong Wen, Abai Xu, Kai Xu, Bingkun Li and Chunxiao Liu

    Citation: Cellular & Molecular Biology Letters 2016 21:27

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  14. Content type: Short communication

    Cytoglobin (CYGB), a member of the globin family, is thought to protect cells from reactive oxygen and nitrogen species and deal with hypoxic conditions and oxidative stress. However, its molecular mechanisms ...

    Authors: Xin Li, Shanshan Zou, Zhen Li, Gaotai Cai, Bohong Chen, Ping Wang and Wenqi Dong

    Citation: Cellular & Molecular Biology Letters 2016 21:25

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  15. Content type: Review

    Synonymous or silent mutations are often overlooked in genetic analyses for disease-causing mutations unless they are directly associated with potential splicing defects. More recent studies, however, indicate...

    Authors: Rafal Bartoszewski, Jaroslaw Króliczewski, Arkadiusz Piotrowski, Anna Janaszak Jasiecka, Sylwia Bartoszewska, Briana Vecchio-Pagan, Lianwu Fu, Aleksandra Sobolewska, Sadis Matalon, Garry R. Cutting, Steven M. Rowe and James F. Collawn

    Citation: Cellular & Molecular Biology Letters 2016 21:23

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  16. Content type: Research article

    How nutrition and growth factor restriction due to serum depletion affect trophoblast function remains poorly understood. We performed a proteomic differential study of the effects of serum depletion on a firs...

    Authors: Susana Novoa-Herran, Adriana Umaña-Perez, Francesc Canals and Myriam Sanchez-Gomez

    Citation: Cellular & Molecular Biology Letters 2016 21:22

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  17. Content type: Short report

    Long non-coding RNAs (lncRNAs) play critical and complicated roles in the regulation of various biological processes, including chromatin modification, transcription and post-transcriptional processing. Intere...

    Authors: Jiachun Sun, Junqiang Yan, Xiaozhi Yuan, Ruina Yang, Tanyou Dan, Xinshuai Wang, Guoqiang Kong and Shegan Gao

    Citation: Cellular & Molecular Biology Letters 2016 21:21

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  18. Content type: Short report

    As a key subunit of the exocyst complex, Exo70 has highly conserved sequence and is widely found in yeast, mammals, and plants. In yeast, Exo70 mediates the process of exocytosis and promotes anchoring and int...

    Authors: Wenqing Ma, Yu Wang, Xiaomeng Yao, Zijian Xu, Liguo An and Miao Yin

    Citation: Cellular & Molecular Biology Letters 2016 21:20

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  19. Content type: Research

    The aim of this study was to evaluate the influence of RGC-32 (response gene to complement 32) on cell cycle progression in renal tubular epithelial cell injury.

    Authors: Yun-lin Shen, Hua-jie Liu, Lei Sun, Xiao-ling Niu, Xin-yu Kuang, Ping Wang, Sheng Hao and Wen-yan Huang

    Citation: Cellular & Molecular Biology Letters 2016 21:19

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  20. Content type: Mini Review

    Bcl2-associated athanogene 2 (BAG2) shares a similar molecular structure and function with other BAG family members. Functioning as a co-chaperone, it interacts with the ATPase domain of the heat shock protein...

    Authors: Lixia Qin, Jifeng Guo, Qian Zheng and Hainan Zhang

    Citation: Cellular & Molecular Biology Letters 2016 21:18

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  21. Content type: Mini review

    Understanding the cellular pathways that regulate endothelial nitric oxide (eNOS, NOS3) expression and consequently nitric oxide (NO) bioavailability during hypoxia is a necessary aspect in the development of nov...

    Authors: Leszek Kalinowski, Anna Janaszak-Jasiecka, Anna Siekierzycka, Sylwia Bartoszewska, Marcin Woźniak, Dawid Lejnowski, James F. Collawn and Rafal Bartoszewski

    Citation: Cellular & Molecular Biology Letters 2016 21:16

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