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  1. Malignant melanoma (melanoma malignum) is one of the most dangerous types of tumor. It is very difficult to cure. In recent years, a lot of attention has been given to chemoprevention. This method uses natural an...

    Authors: Ewa Chodurek, Arkadiusz Orchel, Joanna Orchel, Sławomir Kurkiewicz, Natalia Gawlik, Zofia Dzierżewicz and Krystyna Stępień
    Citation: Cellular & Molecular Biology Letters 2012 17:33
  2. The minimal vertebrate telomerase enzyme is composed of a protein component (telomerase reverse transcriptase, TERT) and an RNA component (telomerase RNA, TR). Expression of these two subunits is sufficient to...

    Authors: Laetitia Trapp-Fragnet, Delphine T. Marie-Egyptienne, Johans Fakhoury, Denis Rasschaert and Chantal Autexier
    Citation: Cellular & Molecular Biology Letters 2012 17:31
  3. Our study concerns the effects of exposure to lead chloride on the morphology, K+ efflux, SO4 influx and GSH levels of the human erythrocyte. Blood was collected in heparinized tubes and washed ...

    Authors: Tiziana Gugliotta, Grazia De Luca, Pietro Romano, Caterina Rigano, Adriana Scuteri and Leonardo Romano
    Citation: Cellular & Molecular Biology Letters 2012 17:27
  4. DNMT inhibitors are promising new drugs for cancer therapies. In this study, we have observed the antileukemic action of two diverse DNMT inhibitors, the nucleoside agent zebularine and the non-nucleoside agen...

    Authors: Jurate Savickiene, Grazina Treigyte, Veronika-Viktorija Borutinskaite and Ruta Navakauskiene
    Citation: Cellular & Molecular Biology Letters 2012 17:24
  5. Flax is a valuable source of fibers, linseed and oil. The compounds of the latter two products have already been widely examined and have been proven to possess many health-beneficial properties. In the course...

    Authors: Monika Styrczewska, Anna Kulma, Katarzyna Ratajczak, Ryszard Amarowicz and Jan Szopa
    Citation: Cellular & Molecular Biology Letters 2012 17:23
  6. Secretory phospholipases A2 (sPLA2s) are a diverse family of low molecular mass enzymes (13–18 kDa) that hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce free fatty acids and lysophosph...

    Authors: Shigeki Kamitani, Katsutoshi Yamada, Shigenori Yamamoto, Yoshikazu Ishimoto, Takashi Ono, Akihiko Saiga and Kohji Hanasaki
    Citation: Cellular & Molecular Biology Letters 2012 17:19
  7. Oocyte maturation in mammals is a multiple-stage process that generates fertilizable oocytes. Ovarian oocytes are arrested at prophase of the first meiotic division characterized by the presence of a germinal ...

    Authors: Dana Chuderland, Zeev Dvashi, Ruth Kaplan-Kraicer, Daniella Ben-Meir, Ruth Shalgi and Sara Lavi
    Citation: Cellular & Molecular Biology Letters 2012 17:22
  8. Activation of the Hsp90 chaperone system is a characteristic of cancer cells. The regulation of chaperone activities involves their interaction with cochaperones; therefore we investigated the expression of Hs...

    Authors: Eva Ruckova, Petr Muller, Rudolf Nenutil and Borivoj Vojtesek
    Citation: Cellular & Molecular Biology Letters 2012 17:21
  9. Apoptosis is intimately connected to cell cycle regulation via the Retinoblastoma (Rb)-E2F pathway and thereby serves an essential role in tumor suppression by eliminating aberrant hyperproliferative cells. Upon ...

    Authors: Liza D. Morales, Karina Pena, Dae Joon Kim and Jonathan H. Lieman
    Citation: Cellular & Molecular Biology Letters 2012 17:20
  10. Aggregated amyloid peptides (AP), major components of senile plaques, have been considered to play a very important and crucial role in the development and neuro-pathogenesis of Alzheimer’s disease (AD). In th...

    Authors: Challa Suresh, Johnny Johnson, Roshini Mohan and Chellu S. Chetty
    Citation: Cellular & Molecular Biology Letters 2012 17:18
  11. The gene SPI1, of Saccharomyces cerevisiae, encodes a cell wall protein that is induced in several stress conditions, particularly in the postdiauxic and stationary phases of growth. It has a paralogue, SED1, whi...

    Authors: Fernando Cardona, Marcel.Lí Del Olmo and Agustín Aranda
    Citation: Cellular & Molecular Biology Letters 2012 17:17
  12. Human adipose-derived stem cells (huADSC) were generated from fat tissue of a 65-year-old male donor. Flow cytometry and reverse transcription polymerase chain reaction (RT-PCR) analyses indicated that the huA...

    Authors: Kuo-Liang Yang, Jiunn-Tat Lee, Cheng-Yoong Pang, Ting-Yi Lee, Shee-Ping Chen, Hock-Kean Liew, Shin-Yuan Chen, Tzu-Yung Chen and Py-Yu Lin
    Citation: Cellular & Molecular Biology Letters 2012 17:16
  13. Erythrocytes are constantly exposed to ROS due to their function in the organism. High tension of oxygen, presence of hemoglobin iron and high concentration of polyunsaturated fatty acids in membrane make eryt...

    Authors: Ewa Olchowik, Karol Lotkowski, Saidmukhtar Mavlyanov, Nodira Abdullajanova, Maksim Ionov, Maria Bryszewska and Maria Zamaraeva
    Citation: Cellular & Molecular Biology Letters 2012 17:14
  14. Nitric oxide (NO) is a mediator of a diverse array of inter- and intracellular signal transduction processes. The aim of the present study was to analyze its possible role as a second messenger in the process ...

    Authors: Judit Bátor, Judit Varga, Gergely Berta, Tamar Barbakadze, David Mikeladze, Jeremy Ramsden and József Szeberényi
    Citation: Cellular & Molecular Biology Letters 2012 17:13
  15. The testicular receptor 4 (TR4) is a member of the nuclear receptor superfamily that controls various biological activities. A protective role of TR4 against oxidative stress has recently been discovered. We h...

    Authors: Shian-Jang Yan, Yi-Fen Lee, Huei-Ju Ting, Ning-Chun Liu, Su Liu, Shin-Jen Lin, Shauh-Der Yeh, Gonghui Li and Chawnshang Chang
    Citation: Cellular & Molecular Biology Letters 2012 17:12
  16. To explore the role of the integrin signaling pathway in hepatocytes during rat liver regeneration, the integrin signaling pathway-related gene expression profile in hepatocytes of regenerative liver was detec...

    Authors: Cunshuan Xu, Yanjie Yang, Junying Yang, Xiaoguang Chen and Gaiping Wang
    Citation: Cellular & Molecular Biology Letters 2012 17:11
  17. Anthocyanins are one of the main flavonoid groups. They are responsible for, e.g., the color of plants and have antioxidant features and a wide spectrum of medical activity. The subject of the study was the fo...

    Authors: Dorota Bonarska-Kujawa, Hanna Pruchnik and Halina Kleszczyńska
    Citation: Cellular & Molecular Biology Letters 2012 17:10
  18. This study investigated the role of autophagy in the survival of the invasive bacterium Brucella melitensis strain 16M in murine macrophages. Here, Brucella melitensis 16M was found to trigger autophagosome forma...

    Authors: Fei Guo, Hui Zhang, Chuangfu Chen, Shengwei Hu, Yuanzhi Wang, Jun Qiao, Yan Ren, Ke Zhang, Yong Wang and Guoqing Du
    Citation: Cellular & Molecular Biology Letters 2012 17:9
  19. Aqueous-saline human placenta extract (HPE) is known to possess antioxidant activity due to the high concentration of bioactive substances. This fact allows its application in clinical practice in order to tre...

    Authors: Svitlana Rozanova, Yana Cherkashina, Svitlana Repina, Katherina Rozanova and Oleg Nardid
    Citation: Cellular & Molecular Biology Letters 2012 17:7
  20. Preservation of hepatocyte functions in vitro will undoubtedly help the management of acute liver failure. The coculture system may be able to prevent functional decline of hepatocytes. It has already been shown ...

    Authors: Xia Chen, Shichang Zhang, Tao Liu, Yong Liu and Yingjie Wang
    Citation: Cellular & Molecular Biology Letters 2012 17:4
  21. Enhanced fucosyltransferase IV (FUT4) expression correlates with increased tumor malignancy in many carcinomas. However, little is known about the regulation of FUT4 expression, and whether FUT4 expression is inf...

    Authors: Hongyan Li, Shaoming Tong, Jiwei Liu, Li Han, Xuesong Yang, Hesheng Hou, Qiu Yan and Xiao-Qi Wang
    Citation: Cellular & Molecular Biology Letters 2012 17:3
  22. Highly concentrated urine may induce a harmful effect on the urinary bladder. Therefore, we considered osmolarity of the urine as a basic pathomechanism of mucosal damage. The influence of both cyclophosphamid...

    Authors: Kajetan Juszczak, Jolanta Kaszuba-Zwoińska, Paulina Chorobik, Agata Ziomber and Piotr Jan Thor
    Citation: Cellular & Molecular Biology Letters 2012 17:2
  23. Inositol 1,4,5-trisphosphate receptor type 1 (IP3R1) is already known to be highly expressed in the brain, and is found in many other tissues, including the atrium of the heart. Although the complete primary stru...

    Authors: Krishna P. Subedi, Thoudam Debraj Singh, Joon-Chul Kim and Sun-Hee Woo
    Citation: Cellular & Molecular Biology Letters 2011 17:43
  24. Biogenic membranes or self-synthesizing membranes are the site of synthesis of new lipids such as the endoplasmic reticulum (ER) in eukaryotes. Newly synthesized phospholipids (PLs) at the cytosolic leaflet of...

    Authors: Archita Rajasekharan and Sathyanarayana N. Gummadi
    Citation: Cellular & Molecular Biology Letters 2011 17:42
  25. Virus-induced gene silencing is an important tool for functional gene analysis and the vector based on Barley stripe mosaic virus (BSMV) is widely used for the purpose in monocots. Of the tripartite BSMV genome, ...

    Authors: Adam Kawalek, Marta Dmochowska-Boguta, Anna Nadolska-Orczyk and Waclaw Orczyk
    Citation: Cellular & Molecular Biology Letters 2011 17:41
  26. The emerging fields of tissue engineering and biomaterials have begun to provide potential treatment options for liver failure. The goal of the present study is to investigate the ability of a poly L-lactic ac...

    Authors: Mahboobe Ghaedi, Masoud Soleimani, Iman Shabani, Yuyou Duan and Abbas S. Lotfi
    Citation: Cellular & Molecular Biology Letters 2011 17:40
  27. P5 ATPases (ATP13A1 through ATP13A5) are found in all eukaryotes. They are currently poorly characterized and have unknown substrate specificity. Recent evidence has linked two P5 ATPases to diseases of the nervo...

    Authors: Lisa S. Weingarten, Hardi Dave, Hongyan Li and Dorota A. Crawford
    Citation: Cellular & Molecular Biology Letters 2011 17:39
  28. The purpose of these studies was to determine the effect of polyphenols contained in extracts from apple, strawberry and blackcurrant on the properties of the erythrocyte membrane, treated as a model of the bi...

    Authors: Sylwia Cyboran, Jan Oszmiański and Halina Kleszczyńska
    Citation: Cellular & Molecular Biology Letters 2011 17:38
  29. Diphtheria toxin (DT) and its N-terminal fragment A (FA) catalyse the transfer of the ADP-ribose moiety of nicotinamide adenine dinucleotide (NAD) into a covalent linkage with eukaryotic elongation factor 2 (e...

    Authors: Başak Varol, Muhammet Bektaş, Rüstem Nurten and Engin Bermek
    Citation: Cellular & Molecular Biology Letters 2011 17:36
  30. Tumor establishment and penetration consists of a series of complex processes involving multiple changes in gene expression and protein modification. Proteome changes of tumor tissue were investigated after in...

    Authors: Jihye Lee, Gunsup Lee, Jin Hee Park, Sukchan Lee, Chang-Hwan Yeom, Byungjo Na and Seyeon Park
    Citation: Cellular & Molecular Biology Letters 2011 17:35
  31. Thy28 protein is conserved among plants, bacteria, and mammalian cells. Nuclear Thy28 protein is substantially expressed in testis, liver, and immune cells such as lymphocytes. Lymphocyte apoptosis plays a cru...

    Authors: Hiroko Toyota, Xiao-Zhou Jiang, Hideki Asakura and Junichiro Mizuguchi
    Citation: Cellular & Molecular Biology Letters 2011 17:34
  32. Anucleated erythrocytes were long considered as oxygen-transporting cells with limited regulatory functions. Components of different nuclear signaling pathways have not been investigated in those cells, yet. S...

    Authors: Mehrdad Ghashghaeinia, Mahmoud Toulany, Mohammad Saki, H. Peter Rodemann, Ulrich Mrowietz, Florian Lang and Thomas Wieder
    Citation: Cellular & Molecular Biology Letters 2011 17:32
  33. Dendrimers, highly branched macromolecules with a specific size and shape, provide many exciting opportunities for biomedical applications. However, most dendrimers demonstrate toxic and haemolytic activity be...

    Authors: Barbara Ziemba, Gabriela Matuszko, Maria Bryszewska and Barbara Klajnert
    Citation: Cellular & Molecular Biology Letters 2011 17:33
  34. The evolutionarily-conserved protein phosphatase 1 (PP1) plays a central role in dephosphorylation of phosphoproteins during the M phase of the cell cycle. We demonstrate here that the PP1 inhibitor inhibitor-...

    Authors: Arian Khandani, Mahmood Mohtashami and Anne Camirand
    Citation: Cellular & Molecular Biology Letters 2011 16:669
  35. Recent results obtained in various crops indicate that real-time PCR could be a powerful tool for the detection and characterization of transgene locus structures. The determination of transgenic locus number ...

    Authors: Agata Gadaleta, Angelica Giancaspro, Maria Francesca Cardone and Antonio Blanco
    Citation: Cellular & Molecular Biology Letters 2011 16:652
  36. Kindlin-2 is a recently identified FERM and PH domain containing integrin interacting protein. Kindlin-2 is ubiquitously expressed in normal tissues. So far, much effort has been spent exploring the functional...

    Authors: Ammad Aslam Khan, Takashi Shimokawa, Staffan Strömblad and Hongquan Zhang
    Citation: Cellular & Molecular Biology Letters 2011 16:638
  37. The formation of aqueous intercellular channels mediating gap junctional intercellular coupling (GJIC) is a canonical function of connexins (Cx). In contrast, mechanisms of GJIC-independent involvement of conn...

    Authors: Katarzyna Szpak, Ewa Wybieralska, Ewa Niedziałkowska, Monika Rak, Iga Bechyne, Marta Michalik, Zbigniew Madeja and Jarosław Czyż
    Citation: Cellular & Molecular Biology Letters 2011 16:625
  38. This study aimed to determine the changes in the expression of genes for selected specific transcriptional factors that have both activating and repressing functions in in vitro ductal breast cancer cells, under ...

    Authors: Marta Ziaja-Sołtys and Jolanta Rzymowska
    Citation: Cellular & Molecular Biology Letters 2011 16:610
  39. The use of tissue-specific promoter elements in the treatment of cervical cancer has been explored in this paper. The P105 promoter of human papillomavirus 18 (HPV18) was utilised to direct tissue-specific expres...

    Authors: Mandy S. Y. Lung, Wendy M. Mak and Vincent Murray
    Citation: Cellular & Molecular Biology Letters 2011 16:18
  40. Yeast two-hybrid (Y2H) and isothermal titration calorimetry (ITC) methods were used to further study the mutational effect of non-erythroid alpha spectrin (αII) at position 22 in tetramer formation with beta s...

    Authors: Akin Sevinc, Marta A. Witek and Leslie W. -M. Fung
    Citation: Cellular & Molecular Biology Letters 2011 16:17
  41. Published data concerning the effects of hypertonicity on cell motility have often been controversial. The interpretation of results often rests on the premise that cell responses result from cell dehydration,...

    Authors: Włodzimierz Korohoda, Magdalena Kucia, Ewa Wybieralska, Magdalena Wianecka-Skoczeń, Agnieszka Waligórska, Justyna Drukała and Zbigniew Madeja
    Citation: Cellular & Molecular Biology Letters 2011 16:15
  42. We used a continuum model based on the Helfrich free energy to investigate the binding dynamics of a lipid bilayer to a BAR domain surface of a crescent-like shape of positive (e.g. I-BAR shape) or negative (e...

    Authors: Doron Kabaso, Ekaterina Gongadze, Jernej Jorgačevski, Marko Kreft, Ursula Van Rienen, Robert Zorec and Aleš Iglič
    Citation: Cellular & Molecular Biology Letters 2011 16:13
  43. The tight junction protein claudin-4 is frequently overexpressed in pancreatic cancer, and is also a receptor for Clostridium perfringens enterotoxin (CPE). The cytotoxic effects of CPE are thought to be useful a...

    Authors: Hiroshi Yamaguchi, Takashi Kojima, Tatsuya Ito, Daisuke Kyuno, Yasutoshi Kimura, Masafumi Imamura, Koichi Hirata and Norimasa Sawada
    Citation: Cellular & Molecular Biology Letters 2011 16:14

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