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  1. Ionizing radiation is one of the types of oxidative stress that has a number of damaging effects on cutaneous tissues. One of the histological features of radiation-induced cutaneous fibrosis is the accumulati...

    Authors: Fumiaki Nakayama, Akiko Hagiwara, Tetsuo Yamamoto and Makoto Akashi
    Citation: Cellular & Molecular Biology Letters 2008 13:16
    Content type: Research Article Published on:

  2. The relationship between plasma lipid levels and mortality from cardiovascular diseases has been shown in many studies, but there has been far less investigation into their relationship to non-cardiovascular d...

    Authors: Małgorzata Kuliszkiewicz-Janus, Rafał Małecki and Abdulrahman Saeed Mohamed
    Citation: Cellular & Molecular Biology Letters 2008 13:14
    Content type: Research Article Published on:

  3. The laminin-binding protein, variously called the 37/67-kDa high affinity laminin receptor or p40, mediates the attachment of normal cells to the laminin network, and also has a role as a ribosomal protein. Ov...

    Authors: Tharinee Susantad and Duncan R. Smith
    Citation: Cellular & Molecular Biology Letters 2008 13:17
    Content type: Research Article Published on:

  5. Patients with malignancy typically exhibit abnormal dendritic cell profiles. Interstitial tumor pressure is increased 20-50mmHg over that in normal tissue. We hypothesized that elevated pressure in the tumor m...

    Authors: David H. Craig, Keri L. Schaubert, Hiroe Shiratsuchi, June Kan-Mitchell and Marc D. Basson
    Citation: Cellular & Molecular Biology Letters 2008 13:54
    Content type: Research Article Published on:

  6. Mouse chondrolectin (chodl) was isolated out of the tail tip of four-day old 129/SvJ mice as a by-product of a PCR-based subtractive cDNA library screening. The gene is predominantly expressed in adult skeletal m...

    Authors: An Claessens, Christine Weyn and Joseph Merregaert
    Citation: Cellular & Molecular Biology Letters 2008 13:52
    Content type: Research Article Published on:

  7. Abstract: Previously, we identified a novel correlation between the upregulated expression of telomerase (hTERT) and cytochrome P450 1A1 (CYP1A1) in A549 human lung cancer cell line. The expression correlation wa...

    Authors: Kulthum Mohammed and Amal Shervington
    Citation: Cellular & Molecular Biology Letters 2008 13:50
    Content type: Research Article Published on:

  8. The aim of this study was to evaluate the effect of carvedilol on the enzymatic antioxidative defence and plasma antioxidative activity in patients with stable angina. The study comprised 30 patients, aged 37–...

    Authors: Jan Kowalski, Maciej Banach, Marcin Barylski, Robert Irzmanski and Lucjan Pawlicki
    Citation: Cellular & Molecular Biology Letters 2008 13:49
    Content type: Research article Published on:

  9. Proteases, also referred to as peptidases, are the enzymes that catalyse the hydrolysis of peptide bonds in polipeptides. A variety of biological functions and processes depend on their activity. Regardless of...

    Authors: Benedykt Władyka and Katarzyna Pustelny
    Citation: Cellular & Molecular Biology Letters 2008 13:48
    Content type: Review Published on:

  10. The natriuretic peptide family comprises atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), C-type natriuretic peptide (CNP), dendroaspis natriuretic peptide (DNP), and urodilatin. The activiti...

    Authors: Mariusz Piechota, Maciej Banach, Anna Jacoń and Jacek Rysz
    Citation: Cellular & Molecular Biology Letters 2008 13:46
    Content type: Review Article Published on:

  11. In this study, we investigated apoptosis induced in human trisomic and diabetic fibroblasts by daunorubicin (DNR) and its derivative, idarubicin (IDA). The cells were incubated with DNR or IDA for 2 h and then...

    Authors: Sylwia Dragojew, Agnieszka Marczak, Janusz Maszewski, Krzysztof Ilnicki and Zofia Jóźwiak
    Citation: Cellular & Molecular Biology Letters 2008 13:45
    Content type: Research Article Published on:

  12. Altered tissue water homeostasis may contribute to edema formation during various stresses including bacterial infection. We observed induction of aquaporin-1 (AQP1) during Staphylococcus aureus infection of cult...

    Authors: Kelly Schweitzer, Erran Li, Venkataramana Sidhaye, Virginia Leitch, Sergey Kuznetsov and Landon S. King
    Citation: Cellular & Molecular Biology Letters 2008 13:44
    Content type: Research Article Published on:

  13. This study focused on the function of hnRNP-R in the regulation of c-fos expression. We demonstrated that hnRNP-R accelerated the rise and decline phases of c-fos mRNAs and Fos proteins, allowing PMA to induce an...

    Authors: Jia Huang, Shu-Jing Li, Xian-Hua Chen, Yu Han and Ping Xu
    Citation: Cellular & Molecular Biology Letters 2008 13:2
    Content type: Short Communication Published on:

  14. Although there are many reports about the efficacy of siRNAs, it is not clear whether those siRNAs with high C/G contents can be used to silence their target mRNAs efficiently. In this study, we investigated t...

    Authors: Jie-Ying Liao, James Q. Yin, Fang Chen, Tie-Gang Liu and Jia-Chang Yue
    Citation: Cellular & Molecular Biology Letters 2008 13:1
    Content type: Research Article Published on:

  15. Membranes made from binary mixtures of egg sphingomyelin (ESM) and cholesterol were investigated using conventional and saturation-recovery EPR observations of the 5-doxylstearic acid spin label (5-SASL). The ...

    Authors: Anna Wisniewska and Witold K. Subczynski
    Citation: Cellular & Molecular Biology Letters 2008 13:12
    Content type: Research article Published on:

  16. Ionic channels form pores in biomembranes. These pores are large macromolecular structures. Due to thermal fluctuations of countless degrees-of-freedom of the biomembrane material, the actual form of the pores...

    Authors: Aleksander Wozinski and Jan Iwaniszewski
    Citation: Cellular & Molecular Biology Letters 2008 13:10
    Content type: Short communication Published on:

  17. p73, a member of the p53 family, exhibits activities similar to those of p53, including the ability to induce growth arrest and apoptosis. p73 influences chemotherapeutic responses in human cancer patients, in...

    Authors: Jitka Holcakova, Pavla Ceskova, Roman Hrstka, Petr Muller, Lenka Dubska, Philip J. Coates, Emil Palecek and Borivoj Vojtesek
    Citation: Cellular & Molecular Biology Letters 2008 13:11
    Content type: Research Article Published on:

  18. The human ZNF300 gene is a member of the KRAB/C2H2 zinc finger gene family, the members of which are known to be involved in various developmental and pathological processes. Here, we show that the ZNF300 gene en...

    Authors: Hongling Qiu, Lu Xue, Li Gao, Huanjie Shao, Di Wang, Mingxiong Guo and Wenxin Li
    Citation: Cellular & Molecular Biology Letters 2008 13:5
    Content type: Research Article Published on:

  19. Malignant prostate tissues have markedly reduced zinc (Zn2+) contents in comparison to non-malignant tissues. In this study, we restored a high intracellular Zn2+ level to LNCaP prostate cancer cells by culturing...

    Authors: Pooi-Fong Wong and Sazaly Abubakar
    Citation: Cellular & Molecular Biology Letters 2008 13:9
    Content type: Research Article Published on:

  21. This report describes an improvement made to the horizontal cell electrophoresis methodology. It involves using two liquid layers differing in density to produce an interface described as a “density cushion”. ...

    Authors: Anna Wilk, Katarzyna Urbańska, David E. Woolley and Włodzimierz Korohoda
    Citation: Cellular & Molecular Biology Letters 2008 13:7
    Content type: Short communication Published on:

  22. STGC3 is a novel candidate tumor suppressor gene that was found to be associated with nasopharyngeal carcinoma (NPC) via the cDNA cloning and RACE processes. The biological function of th...

    Authors: Xiu-Sheng He, Min Deng, Shuai Yang, Zhi-Qiang Xiao, Qiao Luo, Zhi-min He, Bo Hu and Zhu-Chu Chen
    Citation: Cellular & Molecular Biology Letters 2008 13:6
    Content type: Research Article Published on:

  24. Apigenin (4′,5,7,-trihydroxyflavone) is a flavonoid abundant in the common fruits, herbs and vegetables constituting the bulk of the human diet. This study was aimed at quantifying the effects of apigenin on t...

    Authors: Marta Czernik, Jolanta Sroka, Zbigniew Madeja and Jarosław Czyż
    Citation: Cellular & Molecular Biology Letters 2008 13:3
    Content type: Short communication Published on:

  25. Acellular (true) slime moulds (Myxomycetes) are capable of a transition to the stage of sclerotium — a dormant form of plasmodium produced under unfavourable environmental conditions. In this study, sclerotia of

    Authors: Anna Krzywda, Elżbieta Petelenz, Dominika Michalczyk and Przemysław M. Płonka
    Citation: Cellular & Molecular Biology Letters 2007 13:47
    Content type: Research Article Published on:

  26. Syntaxin 8 has been shown to form the SNARE complex with syntaxin 7, vti1b and endobrevin. These have been shown to function as the machinery for the homotypic fusion of late endosomes. Recently, we showed tha...

    Authors: Kazuo Kasai, Kei Suga, Tetsuro Izumi and Kimio Akagawa
    Citation: Cellular & Molecular Biology Letters 2007 13:43
    Content type: Research Article Published on:

  27. It has been suggested that Bax translocation to the mitochondria is related to apoptosis, and that cytosol acidification contributes to apoptosis events. However, the mechanisms remain obscure. We investigated...

    Authors: Lin Yang, Yongyu Mei, Qifeng Xie, Xiaoyan Han, Fucheng Zhang, Lin Gu, Yufeng Zhang, Youming Chen, Gang Li and Zhiliang Gao
    Citation: Cellular & Molecular Biology Letters 2007 13:42
    Content type: Research Article Published on:

  28. Transcription reinitiation by RNA polymerase (Pol) III proceeds through facilitated recycling, a process by which the terminating Pol III, assisted by the transcription factors TFIIIB and TFIIIC, rapidly reloa...

    Authors: Roberto Ferrari and Giorgio Dieci
    Citation: Cellular & Molecular Biology Letters 2007 13:41
    Content type: Short Communication Published on:

  29. The results of several experimental studies have shown that ascorbic acid inhibits tumor growth and metastasis. Ascorbic acid is an antioxidant that acts as a scavenger for a wide range of reactive oxygen spec...

    Authors: Ewa Wybieralska, Monika Koza, Jolanta Sroka, Jarosław Czyż and Zbigniew Madeja
    Citation: Cellular & Molecular Biology Letters 2007 13:40
    Content type: Short Communication Published on:

  31. Cloning using bacterial artificial chromosomes (BACs) can yield high quality genomic libraries, which are used for the physical mapping, identification and isolation of genes, and for gene sequencing. A BAC ge...

    Authors: Wojciech Gutman, Magdalena Pawełkowicz, Rafał Woycicki, Ewa Piszczek and Zbigniew Przybecki
    Citation: Cellular & Molecular Biology Letters 2007 13:38
    Content type: Research Article Published on:

  32. Organotin compounds are chemicals that are widely used in industry and agriculture as plastic stabilizers, catalysts and biocides. Many of them, including tributyltin (TBT), have been detected in human food an...

    Authors: Jolanta Sroka, Przemysław Włosiak, Anna Wilk, Justyna Antonik, Jarosław Czyż and Zbigniew Madeja
    Citation: Cellular & Molecular Biology Letters 2007 13:37
    Content type: Short Communication Published on:

  33. The aim of this investigation was to evaluate the changes in PAF concentrations in the plasma, PBMC and BMMC of patients with acute lymphoblastic leukemia (ALL) and acute myeloblastic leukemia (AML). The plasm...

    Authors: Małgorzata Kuliszkiewicz-Janus, Mariusz Adam Tuz, Marek Kiełbiński, Stanisław Baczyński, Bożena Jaźwiec and Helena Śladowska
    Citation: Cellular & Molecular Biology Letters 2007 13:35
    Content type: Short Communication Published on:

  34. We previously demonstrated that caspase-3, an executioner of apoptosis, is activated in the pressure-induced apoptosis of murine erythroleukemia (MEL) cells (at 100 MPa). Here, we examined the pathway of caspa...

    Authors: Takeo Yamaguchi, Kenji Hashiguchi, Satoshi Katsuki, Wakako Iwamoto, Shoichiro Tsuruhara and Shigeyuki Terada
    Citation: Cellular & Molecular Biology Letters 2007 13:34
    Content type: Short Communication Published on:

  35. We cultured calnexin-disrupted and wild-type Saccharomyces cerevisiae strains under conditions of heat stress. The growth rate of the calnexin-disrupted yeast was almost the same as that of the wild-type yeast un...

    Authors: Huili Zhang, Jianwei He, Yanyan Ji, Akio Kato and Youtao Song
    Citation: Cellular & Molecular Biology Letters 2007 13:33
    Content type: Research Article Published on:

  36. Alcoholic liver disease (ALD) is one of the most common diseases in modern society. A large number of studies are in progress aiming to identify natural substances that would be effective in reducing the sever...

    Authors: Nadana Saravanan and Namasivayam Nalini
    Citation: Cellular & Molecular Biology Letters 2007 13:32
    Content type: Research Article Published on:

  37. Osteopontin (OPN) is a secreted, non-collagenous, sialic acid-rich protein which functions by mediating cell-matrix interactions and cellular signaling via binding with integrins and CD44 receptors. An increas...

    Authors: Si-Jin Liu, Dao-Qiang Zhang, Xiu-Mei Sui, Lin Zhang, Zi-Wei Cai, Li-Qiu Sun, Ya-Jun Liu, Yan Xue and Guo-Fa Hu
    Citation: Cellular & Molecular Biology Letters 2007 13:31
    Content type: Short Communication Published on:

  38. Bilirubin, an antioxidant in the blood, plays a role in protection from atherosclerosis. The level of bilirubin is highly correlated to the incidence of coronary artery disease (CAD). Unconjugated bilirubin is...

    Authors: Chia-Jung Hsieh, Meng-Jung Chen, Yung-Liang Liao and Tung-Nan Liao
    Citation: Cellular & Molecular Biology Letters 2007 13:30
    Content type: Short Communication Published on:

  40. The complete nucleotide sequence of the cucumber (C. sativus L. var. Borszczagowski) chloroplast genome has been determined. The genome is composed of 155,293 bp containing a pair of inverted repeats of 25,191 bp...

    Authors: Wojciech Pląder, Yasushi Yukawa, Masahiro Sugiura and Stefan Malepszy
    Citation: Cellular & Molecular Biology Letters 2007 12:29
    Content type: Research Article Published on:

  42. Endothelin (ET), originally characterized as a vasoconstrictive peptide, has been found to have many different biological functions, including acting as a local hormonal regulator of pressure, fluid, ions and ...

    Authors: Yan Luo, Yuedi Tang, Qingjie Xia and Jin Liu
    Citation: Cellular & Molecular Biology Letters 2007 12:27
    Content type: Short Communication Published on:

  43. Chaetognaths constitute a small marine phylum of approximately 120 species. Two classes of both 18S and 28S rRNA gene sequences have been evidenced in this phylum, even though significant intraindividual varia...

    Authors: Roxane-Marie Barthélémy, Michel Grino, Pierre Pontarotti, Jean-Paul Casanova and Eric Faure
    Citation: Cellular & Molecular Biology Letters 2007 12:26
    Content type: Short Communication Published on:

  44. A novel approach to DNase I-sensitivity analysis was applied to examining genes of the spermatogenic pathway, reflective of the substantial morphological and genomic changes that occur during this program of d...

    Authors: Rui Pires Martins, Adrian E. Platts and Stephen A. Krawetz
    Citation: Cellular & Molecular Biology Letters 2007 12:24
    Content type: Research Article Published on:

  45. The type 1 insulin-like growth factor receptor (IGF-1R), which is over-expressed or activated in many human cancers, including lung cancer, mediates cancer cell proliferation and metastasis. Several studies in...

    Authors: Zhiyuan Ma, Aiqiang Dong, Minjian Kong and Jianfang Qian
    Citation: Cellular & Molecular Biology Letters 2007 12:22
    Content type: Research Article Published on:

  47. This study was conducted in order to identify quantitative trait loci (QTLs) for the in vitro culture response of winter rye (Secale cereale L.) immature embryos and immature inflorescences. A genetic linkage map...

    Authors: Hanna Bolibok, Anna Gruszczyńska, Aneta Hromada-Judycka and Monika Rakoczy-Trojanowska
    Citation: Cellular & Molecular Biology Letters 2007 12:23
    Content type: Research Article Published on:

  48. Human PCAN1 (prostate cancer gene 1) is a prostate-specific gene that is highly expressed in prostate epithelial tissue, and frequently mutated in prostate tumors. To better understand the regulation of the PCAN1

    Authors: Wenwen Liu, Weiwen Chen, Pengju Zhang, Chunxiao Yu, Feng Kong, Jingti Deng, Jianye Zhang and Anli Jiang
    Citation: Cellular & Molecular Biology Letters 2007 12:16
    Content type: OriginalPaper Published on:

  49. Ion channels selective for chloride ions are present in all biological membranes, where they regulate the cell volume or membrane potential. Various chloride channels from mitochondrial membranes have been des...

    Authors: Izabela Koszela-Piotrowska, Katarzyna Choma, Piotr Bednarczyk, Krzysztof Dołowy, Adam Szewczyk, Wolfram S. Kunz, Lubica Malekova, Viera Kominkova and Karol Ondrias
    Citation: Cellular & Molecular Biology Letters 2007 12:19
    Content type: OriginalPaper Published on:

  50. We studied the influence of Withania somnifera (Ws) root extract (100 mg/kg body weight) on parkinsonism induced by 1-methyl 4-phenyl 1,2,3,6-tetrahydropyridine (MPTP; i.p, 20 mg/kg body weight for 4 days), via t...

    Authors: Srinivasagam Raja Sankar, Thamilarasan Manivasagam, Arumugam Krishnamurti and Manickam Ramanathan
    Citation: Cellular & Molecular Biology Letters 2007 12:15
    Content type: Short Communication Published on:

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