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  1. MicroRNAs play important roles in regulation of the cardiovascular system. The purpose of this study was to investigate microRNA-320 (miR-320) expression in myocardial ischemia-reperfusion (I/R) injury and the...

    Authors: Zhi-Qiang Tian, Hong Jiang and Zhi-Bing Lu

    Citation: Cellular & Molecular Biology Letters 2018 23:41

    Content type: Research

    Published on:

  2. Imbalances in circulating T lymphocytes play critical roles in the pathogenesis of hypertension-mediated inflammation. Connexins (Cxs) in immune cells are involved in the maintenance of homeostasis of T lympho...

    Authors: Xin Ni, Xin-zhi Li, Zhi-ru Fan, Ai Wang, Hai-chao Zhang, Liang Zhang, Li LI, Jun-qiang Si and Ke-tao Ma

    Citation: Cellular & Molecular Biology Letters 2018 23:40

    Content type: Research

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  3. The transcription factor Oct4 plays a pivotal role in the pre-implantation development of the mouse embryo. DNA methyltransferase 1 (Dnmt1) maintains the changes in DNA methylation during mammalian early embry...

    Authors: Fengrui Wu, Qingqing Wu, Dengkun Li, Yuan Zhang, Rong Wang, Yong Liu and Wenyong Li

    Citation: Cellular & Molecular Biology Letters 2018 23:39

    Content type: Research

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  4. Inflammation is an important pathogenic component of endotoxemia-induced acute kidney injury (AKI), finally resulting in renal failure. Diacerein is an interleukin-1β (IL-1β) inhibitor used for osteoarthritis ...

    Authors: Guangzhe Yu, Qian Liu, Xuening Dong, Kaihong Tang, Bohui Li, Chunmei Liu, Wenzheng Zhang, Yiduo Wang and Yingyu Jin

    Citation: Cellular & Molecular Biology Letters 2018 23:38

    Content type: Research

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  5. Oncogenic Notch1 is known to activate the NF-κB pathway in T cell acute lymphoblastic leukemia (T-ALL) and to up-regulate the transcription of Asb2α, a specificity factor for an E3 ubiquitin ligase complex tha...

    Authors: Wei Wu, Li Nie, Li Zhang and Yan Li

    Citation: Cellular & Molecular Biology Letters 2018 23:37

    Content type: Short report

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  8. Upregulation of histone acetylation plays a critical role in the dysregulation of transcription. It alters the structure of chromatin, which leads to the onset of cancer. Histone deacetylase inhibitors may the...

    Authors: Ying Huang, Wuping Yang, Huihong Zeng, Chuan Hu, Yaqiong Zhang, Nanhua Ding, Guangqin Fan, Lijian Shao and Bohai Kuang

    Citation: Cellular & Molecular Biology Letters 2018 23:34

    Content type: Short report

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  10. Recent findings indicate that dentin sialophosphoprotein (DSPP) and matrix metalloproteinase (MMP) 20 interact in oral squamous cell carcinoma (OSCC). The objective of this study was to determine the effects o...

    Authors: Nikolaos G. Nikitakis, Ioannis Gkouveris, Jaya Aseervatham, Kelvin Barahona and Kalu U. E. Ogbureke

    Citation: Cellular & Molecular Biology Letters 2018 23:30

    Content type: Short report

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  11. Lamin proteins are type V intermediate filament proteins (IFs) located inside the cell nucleus. They are evolutionarily conserved and have similar domain organization and properties to cytoplasmic IFs. Lamins ...

    Authors: Marta Pałka, Aleksandra Tomczak, Katarzyna Grabowska, Magdalena Machowska, Katarzyna Piekarowicz, Dorota Rzepecka and Ryszard Rzepecki

    Citation: Cellular & Molecular Biology Letters 2018 23:32

    Content type: Review

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  12. Bamei pigs are special germplasm resources in Qinghai. In the specific environment of the Qinghai plateau, local breeds, through long-term natural and artificial selection, have acquired a relatively stable po...

    Authors: Junxia Zhang, Baochun Yang, Xiaocheng Wen and Guoqiang Sun

    Citation: Cellular & Molecular Biology Letters 2018 23:31

    Content type: Short report

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  13. Mishandling of intracellular chloride (Cl−) concentration ([Cl−]i) in cerebrovascular smooth muscle cells is implicated in several pathological processes, including hyperplasia and remodeling. We investigated the...

    Authors: Jingjing Lu, Feng Xu, Yingna Zhang, Hong Lu and Jiewen Zhang

    Citation: Cellular & Molecular Biology Letters 2018 23:29

    Content type: Research

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  15. Radiotherapy is among the commonly applied treatment options for glioma, which is one of the most common types of primary brain tumor. To evaluate the effect of radiotherapy noninvasively, it is vital for onco...

    Authors: Hongxia Li, Yi Cui, Fuyan Li, Wenqi Shi, Wenjing Gao, Xiao Wang and Qingshi Zeng

    Citation: Cellular & Molecular Biology Letters 2018 23:27

    Content type: Research

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  16. Hypoxia plays a critical role in many cancers. Hypoxia inducible factor-1α (HIF-1α) is an important mediator of the hypoxia response. It regulates the expression of various chemokines involved in tumor growth,...

    Authors: Wenming Feng, Tao Xue, Sanxiong Huang, Qilin Shi, Chengwu Tang, Ge Cui, Guanghui Yang, Hui Gong and Huihui Guo

    Citation: Cellular & Molecular Biology Letters 2018 23:26

    Content type: Short report

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  17. Although significant advances have been made in understanding the mechanisms of macrophage response to Staphylococcus aureus infection, the molecular details are still elusive. Identification of the essential gen...

    Authors: Aixia Sun, Hongwei Zhang, Feng Pang, Guifen Niu, Jianzhong Chen, Fei Chen and Jian Zhang

    Citation: Cellular & Molecular Biology Letters 2018 23:25

    Content type: Research

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  18. Patients with anti-β2GPI antibodies display significantly higher platelet activation/aggregation and vascular endothelial cell damage. The mechanism underlying the correlation between platelet activation, vasc...

    Authors: Yanfen Zhang, Wenjing Zhang, Caijun Zha and Yanhong Liu

    Citation: Cellular & Molecular Biology Letters 2018 23:24

    Content type: Short report

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  19. MicroRNAs (miRNAs) have physiological and pathophysiological functions that are involved in the regulation of cardiac fibrosis. This study aimed to investigate the effects of miR-495 on high glucose-induced ca...

    Authors: Xiaowei Wang, Haiying Jin, Shifeng Jiang and Yanlan Xu

    Citation: Cellular & Molecular Biology Letters 2018 23:23

    Content type: Research

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  20. The levels of decoy receptor 3 (DcR3), soluble urokinase type plasminogen activator receptor (suPAR) and procalcitonin (PCT) are significantly increased in sepsis. We investigated the diagnostic value of DcR3 ...

    Authors: Jing-jing Zhao, Xiao-Li Lou, Hong-wei Chen, Feng-ting Zhu and Yan-Qiang Hou

    Citation: Cellular & Molecular Biology Letters 2018 23:22

    Content type: Short report

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  22. Tumourigenic tissue uses modified metabolic signalling pathways in order to support hyperproliferation and survival. Cancer-associated aerobic glycolysis resulting in lactic acid production was described nearl...

    Authors: Mokgadi Violet Gwangwa, Anna Margaretha Joubert and Michelle Helen Visagie

    Citation: Cellular & Molecular Biology Letters 2018 23:20

    Content type: Review

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  23. Osthole is a natural product that has multiple bioactive functions and has been reported to exert potent immunosuppressive effects. However, the therapeutic effect of osthole on arthritis has not been explored...

    Authors: Renguo Xu, Zhen Liu, Jiande Hou, Tao Huang and Ming Yang

    Citation: Cellular & Molecular Biology Letters 2018 23:19

    Content type: Short report

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  24. Lycium barbarum polysaccharide (LBP) is considered an antioxidant agent. NF-E2-related factor-2 (Nrf2) is an important regulator for protection against UV damage. In this study, we verified the performance of LBP...

    Authors: Bihua Liang, Liqian Peng, Runxiang Li, Huaping Li, Ziyin Mo, Xinyue Dai, Na Jiang, Qing Liu, Erting Zhang, Huiyan Deng, Zhenjie Li and Huilan Zhu

    Citation: Cellular & Molecular Biology Letters 2018 23:18

    Content type: Short report

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  25. Epstein–Barr virus (EBV) infection is causatively associated with a variety of human cancers, including gastric cancer (GC), which has one of the highest mortality rates of all human cancers. Long non-coding R...

    Authors: Jing Liu, Chunxia Yang, Yufang Gu, Chong Li, Huamei Zhang, Wenfang Zhang, Xueqing Wang, Nan Wu and Chunyan Zheng

    Citation: Cellular & Molecular Biology Letters 2018 23:17

    Content type: Research

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  26. The miRNA cluster miR-17-92 is known to act as an oncogene in various cancers. Members of this cluster were also found to be involved in some other pathological process, such as steatosis, which is a pivotal e...

    Authors: Ruijie Gong, Xiaofei Lv and Fengqiong Liu

    Citation: Cellular & Molecular Biology Letters 2018 23:16

    Content type: Short report

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  27. The leaves of Annona purpurea have yielded several alkaloids with anti-aggregation activities against rabbit platelets. This is promising in the search for agents that might act against platelets and reduce the i...

    Authors: Gabriela Sánchez, Omar Estrada, Giovana Acha, Alfonso Cardozo, Franshelle Peña, Marie Christine Ruiz, Fabián Michelangeli and Claudia Alvarado-Castillo

    Citation: Cellular & Molecular Biology Letters 2018 23:15

    Content type: Research

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  28. The regulation of microglial function via mitochondrial homeostasis is important in the development of neuroinflammation. The underlying mechanism for this regulatory function remains unclear. In this study, w...

    Authors: Qingyun Lei, Jian Tan, Shangqing Yi, Na Wu, Yilin Wang and Heng Wu

    Citation: Cellular & Molecular Biology Letters 2018 23:14

    Content type: Research

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  29. Arsenic trioxide (As2O3) has a dramatic therapeutic effect on acute promyelocytic leukemia (APL) patients. It can also cause apoptosis in various tumor cells. This study investigated whether As2O3 has an antitumo...

    Authors: Yuanyuan Sun, Chen Wang, Ligang Wang, Zhibo Dai and Kongbin Yang

    Citation: Cellular & Molecular Biology Letters 2018 23:13

    Content type: Research

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  30. Signal Transducer and Activator of Transcription 3 (STAT3) is a transcription factor with many important functions in the biology of normal and transformed cells. Its regulation is highly complex as it is invo...

    Authors: Michaela Galoczova, Philip Coates and Borivoj Vojtesek

    Citation: Cellular & Molecular Biology Letters 2018 23:12

    Content type: Review

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  31. Articular cartilage has a poor capacity for self-repair, and thus still presents a major challenge in orthopedics. Mesenchymal stem cells (MSCs) are multipotent stem cells with the potential to differentiate i...

    Authors: Ghmkin Hassan, Mohammad Bahjat, Issam Kasem, Chadi Soukkarieh and Majd Aljamali

    Citation: Cellular & Molecular Biology Letters 2018 23:11

    Content type: Short report

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  32. The majority of novel chemotherapeutics target the cell cycle, aiming to effect arrest and cause apoptosis. One such agent, 2-methoxyestradiol (2ME), has been shown to possess anticancer properties against num...

    Authors: Laura Susan Boyd, Devrim Gozuacik and Anna Margaretha Joubert

    Citation: Cellular & Molecular Biology Letters 2018 23:10

    Content type: Research

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  33. Previous studies indicated that cadmium (Cd) increases PI3-kinase/Akt phosphorylation, resulting in an alteration in GSK-3β activity. However, the mechanism of Cd-induced endoplasmic reticulum (ER) stress in n...

    Authors: Seungwoo Kim, Hyosoon Cheon, Sam-Moon Kim and Young-Youl Kim

    Citation: Cellular & Molecular Biology Letters 2018 23:9

    Content type: Short report

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  34. Platelet-derived growth factor-C (PDGF-C) has been shown to be involved in several biological processes, such as embryonic development, wound healing and angiogenesis, as well as in diseases including tumor fo...

    Authors: Tomoaki Kinjo, Chuanhai Sun, Tomomi Ikeda, Takako Ikegami, Yuhki Tada, Tadayuki Akagi, Takashi Yokota and Hiroshi Koide

    Citation: Cellular & Molecular Biology Letters 2018 23:8

    Content type: Research

    Published on:

  35. Osteoarthritis is characterized by the continuous degradation of the articular cartilage. The microRNA miR-448 has been found to be broadly involved in cellular processes, including proliferation, apoptosis, i...

    Authors: Hao Yang, Di Wu, Hua Li, Nan Chen and Yongjun Shang

    Citation: Cellular & Molecular Biology Letters 2018 23:7

    Content type: Research

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  36. Laryngeal cancer tends to have a very poor prognosis due to the unsatisfactory efficacy of chemotherapy for this cancer. Multidrug resistance (MDR) is the main cause of chemotherapy failure. The proto-oncogene...

    Authors: Guodong Li, Xiaoling Hu, Lu Sun, Xin Li, Jianfeng Li, Tongli Li and Xiaohui Zhang

    Citation: Cellular & Molecular Biology Letters 2018 23:6

    Content type: Research

    Published on:

  37. Perineuronal nets (PNNs), which are localized around neurons during development, are specialized forms of neural extracellular matrix with neuroprotective and plasticity-regulating roles. Hyaluronan and proteo...

    Authors: Nazli F. Eskici, Sevim Erdem-Ozdamar and Didem Dayangac-Erden

    Citation: Cellular & Molecular Biology Letters 2018 23:5

    Content type: Research

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  38. Calcitonin gene-related peptide (CGRP) can protect against hyperoxia-induced lung injury, making the upregulation of CGRP a potential therapeutic approach for this type of injury. However, the effects of CGRP ...

    Authors: Shaohua Wang, Hongxing Dang, Feng Xu, Jian Deng and Xuemei Zheng

    Citation: Cellular & Molecular Biology Letters 2018 23:4

    Content type: Research

    Published on:

  39. Endoxifen, an active metabolite of tamoxifen, has been shown to be an effective anti-estrogenic agent in estrogen receptor-positive breast cancer patients. In melanoma, estrogen receptor expression is shown to...

    Authors: Paul Chen, Saifuddin Sheikh, Ateeq Ahmad, Shoukath M. Ali, Moghis U. Ahmad and Imran Ahmad

    Citation: Cellular & Molecular Biology Letters 2018 23:3

    Content type: Short report

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  40. Anti-angiogenesis therapy that targets VEGF is one of the important treatment strategies in advanced ovarian cancer. However, depending on the pharmaceutical agent, treatment can have undesirable side effects....

    Authors: Ying Chen, Lei Zhang, Wen-xin Liu and Ke Wang

    Citation: Cellular & Molecular Biology Letters 2018 23:2

    Content type: Research

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  41. Our previous study showed that during in vitro experiments changes in calcium concentration were associated with apoptosis. We presumed that the calcium ion might play a role as intermediate messenger for apop...

    Authors: Yanan Li, Yu Yan, Fang Liu, Ming Wang, Fumin Feng and Yonghong Xiao

    Citation: Cellular & Molecular Biology Letters 2018 23:1

    Content type: Short report

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  42. The transcription factor TWIST1 plays an important role in the epithelial–mesenchymal transition (EMT) process and in the migration, invasion and metastasis of cancer cells. OCT4, which is a homeobox transcrip...

    Authors: Mohammad Hossein Izadpanah, Mohammad Reza Abbaszadegan, Yasaman Fahim and Mohammad Mahdi Forghanifard

    Citation: Cellular & Molecular Biology Letters 2017 22:33

    Content type: Short report

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  43. Oral squamous cell carcinoma (OSCC) is one of the most common types of malignancy. Semaphorin 3F (SEMA3F) is highly conserved but present at a lower level in various cancers than in healthy tissues. While it h...

    Authors: Yi Liu, Ronghua Li, Kai Yin, Gang Ren and Yongdong Zhang

    Citation: Cellular & Molecular Biology Letters 2017 22:32

    Content type: Short report

    Published on:

  44. The natural dihydroflavonol (+) taxifolin was investigated for its protective effect on Fenton reagent-treated bone marrow-derived mesenchymal stem cells (bmMSCs). Various antioxidant assays were used to deter...

    Authors: Xican Li, Hong Xie, Qian Jiang, Gang Wei, Lishan Lin, Changying Li, Xingmei Ou, Lichan Yang, Yulu Xie, Zhen Fu, Yamei Liu and Dongfeng Chen

    Citation: Cellular & Molecular Biology Letters 2017 22:31

    Content type: Short report

    Published on:

  45. Gliomas are commonly malignant tumors that arise in the human central nervous system and have a low overall five-year survival rate. Previous studies reported that several members of Rab GTPase family are invo...

    Authors: Jian Ge, Qianxue Chen, Baohui Liu, Long Wang, Shenqi Zhang and Baowei Ji

    Citation: Cellular & Molecular Biology Letters 2017 22:30

    Content type: Research

    Published on:

  46. Several recent studies have demonstrated the great potential of bone marrow cells in regenerative medicine, not only for their ability to differentiate to match a damaged cell type, but also because they synth...

    Authors: Yolanda Menéndez-Menéndez, Jesús Otero-Hernández, Jose Antonio Vega, Marcos Pérez-Basterrechea, Silvia Pérez-López, María Álvarez-Viejo and Amaia Ferrero-Gutiérrez

    Citation: Cellular & Molecular Biology Letters 2017 22:29

    Content type: Research

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  47. The development and integration of bio- and chemocatalytic processes to convert renewable or biomass feedstocks into polymers is a vibrant field of research with enormous potential for environmental protection...

    Authors: Aleksandra Marszałek-Harych, Dawid Jędrzkiewicz and Jolanta Ejfler

    Citation: Cellular & Molecular Biology Letters 2017 22:28

    Content type: Review

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  48. Prolyl-hydroxyproline (Pro-Hyp) is one of the major constituents of collagen-derived dipeptides. We previously reported that Pro-Hyp promotes the differentiation of osteoblasts by increasing Runx2, osterix and...

    Authors: Yoshifumi Kimira, Haruka Odaira, Kaho Nomura, Yuri Taniuchi, Naoki Inoue, Sachie Nakatani, Jun Shimizu, Masahiro Wada and Hiroshi Mano

    Citation: Cellular & Molecular Biology Letters 2017 22:27

    Content type: Short report

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  49. Many studies have investigated the characteristics and biological activities of type III interferon (IFN), finding that it has similar features to type I IFN but also unique actions because it is recognized by...

    Authors: Wu-mei Yuan, Wan-ju Zhang, Fen-lian Ma, Jin-song Li, Qian Zhang and Li-shu Zheng

    Citation: Cellular & Molecular Biology Letters 2017 22:26

    Content type: Short report

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  50. The rupture of a brain aneurysm causes bleeding in the subarachnoid space. This is known as aneurysmal subarachnoid hemorrhage (aSAH). We evaluated the association of apolipoprotein E (APOE) polymorphism and the ...

    Authors: Arati Suvatha, Sibin Madathan Kandi, Dhananjaya Ishwara Bhat, Narasinga Rao, Vikas Vazhayil and Chetan Ghati Kasturirangan

    Citation: Cellular & Molecular Biology Letters 2017 22:25

    Content type: Short report

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