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  1. Hypoxic conditions induce the expression of hypoxia-inducible factors (HIFs) that allow cells to adapt to the changing conditions and alter the expression of a number of genes including the cystic fibrosis tra...

    Authors: Sylwia Bartoszewska, Wojciech Kamysz, Bogdan Jakiela, Marek Sanak, Jarosław Króliczewski, Zsuzsa Bebok, Rafal Bartoszewski and James F. Collawn
    Citation: Cellular & Molecular Biology Letters 2017 22:23
  2. TGF-β1 plays an important role in the epithelial–mesenchymal transition (EMT) of epithelial cancers, including non-small cell lung cancer (NSCLC). While the full underlying mechanism remains unclear, miR-9 is ...

    Authors: Hui Wang, Qian Wu, Ying Zhang, Hua-Nan Zhang, Yong-Bin Wang and Wei Wang
    Citation: Cellular & Molecular Biology Letters 2017 22:22
  3. Our previous study found that single-pass membrane protein with coiled-coil domains 1 (C3orf43; XM_006248472.3) was significantly upregulated in the proliferative phase during liver regeneration. This indicate...

    Authors: Chunyan Zhang, Cuifang Chang, Deming Li, Fuchun Zhang and Cunshuan Xu
    Citation: Cellular & Molecular Biology Letters 2017 22:21
  4. Clinicians use clinical and pathological parameters, such as tumour size, grade and nodal status, to make decisions on adjuvant treatments for breast cancer. However, therapeutic decisions based on these featu...

    Authors: Umar Wazir, Kinan Mokbel, Amtul Carmichael and Kefah Mokbel
    Citation: Cellular & Molecular Biology Letters 2017 22:20
  5. One of the microorganisms from dental plaque associated with severe inflammatory responses in infectious endocarditis is Porphyromonas gingivalis. It is a Gram-negative bacteria harvested from chronic periodontit...

    Authors: Gloria Gutiérrez-Venegas, Alfredo Torras-Ceballos, Juan Arturo Gómez-Mora and Berenice Fernández-Rojas
    Citation: Cellular & Molecular Biology Letters 2017 22:19
  6. In mammals, genomic DNA that is roughly 2 m long is folded to fit the size of the cell nucleus that has a diameter of about 10 Î¼m. The folding of genomic DNA is mediated via assembly of DNA-protein complex, ch...

    Authors: Sergey V. Razin and Sergey V. Ulianov
    Citation: Cellular & Molecular Biology Letters 2017 22:18
  7. Retinoblastoma (RB), a childhood cancer, is caused by biallelic mutation of the RB1 gene, but its development is not clearly understood. Furthermore, the presence of a cancer stem cell subpopulation in RB might i...

    Authors: Suganya Sivagurunathan, Jayamuruga Pandian Arunachalam and Subbulakshmi Chidambaram
    Citation: Cellular & Molecular Biology Letters 2017 22:17
  8. Nur-77, a member of the NR4A sub-family of nuclear orphan receptors, is downregulated in the placentae of pre-eclamptic women. Here, we investigate the relevance of Nor-1, Nurr-1 and Nur-77 in trophoblastic ce...

    Authors: Sudha Saryu Malhotra and Satish Kumar Gupta
    Citation: Cellular & Molecular Biology Letters 2017 22:15
  9. Exploring the molecular mechanisms underlying directed differentiation is helpful in the development of clinical applications of mesenchymal stem cells (MSCs). Our previous study on dental tissue-derived MSCs ...

    Authors: Luyuan Jin, Yu Cao, Guoxia Yu, Jinsong Wang, Xiao Lin, Lihua Ge, Juan Du, Liping Wang, Shu Diao, Xiaomeng Lian, Songlin Wang, Rui Dong and Zhaochen Shan
    Citation: Cellular & Molecular Biology Letters 2017 22:14
  10. FFA1 is abundantly expressed in the liver, skeletal muscle, monocytes and nervous system, but is particularly abundant in pancreatic β cells. It is widely believed that FFA1 exerts its regulatory roles in a va...

    Authors: Jing Qian, Yuyang Gu, Chun Wu, Feng Yu, Yuqi Chen, Jingmei Zhu, Xingyi Yao, Chen Bei and Qingqing Zhu
    Citation: Cellular & Molecular Biology Letters 2017 22:13
  11. MicroRNAs (miRNAs) play important roles in the growth and metastasis of colon cancer. It is known that one set of miRNAs are dysregulated in colon cancer cells, but the mechanism of their role in cancer develo...

    Authors: Mingxi Zeng, Linlin Zhu, Liangping Li and Changming Kang
    Citation: Cellular & Molecular Biology Letters 2017 22:12
  12. Human milk is a complex fluid that has developed to satisfy the nutritional requirements of infants. In addition to proteins, lipids, carbohydrates and other biologically active components, breast milk contain...

    Authors: Malgorzata Witkowska-Zimny and Ewa Kaminska-El-Hassan
    Citation: Cellular & Molecular Biology Letters 2017 22:11
  13. H19 is a well-characterized Long noncoding RNA (lncRNA) that has been proven to promote myoblast differentiation in humans and mice. However, its mechanism of action is still not fully interpreted.

    Authors: Xiaochun Xu, Shengyue Ji, Weili Li, Bao Yi, Hengxin Li, Hongfu Zhang and Wenping Ma
    Citation: Cellular & Molecular Biology Letters 2017 22:10
  14. The gene that encodes tumor protein p53, Tp53, is mutated or silenced in most human cancers and is recognized as one of the most important cancer drivers. Homozygotic Tp53 knockout mice, which develop lethal canc...

    Authors: Damian Strzemecki, Magdalena Guzowska and Paweł Grieb
    Citation: Cellular & Molecular Biology Letters 2017 22:9
  15. Squamous cell carcinoma (SCC) is the most common cancer worldwide. The treatment of locally advanced disease generally requires various combinations of radiotherapy, surgery, and systemic therapy. Despite aggr...

    Authors: Zakir Khan, Abdul Arif Khan, Hariom Yadav, Godavarthi B. K. S. Prasad and Prakash Singh Bisen
    Citation: Cellular & Molecular Biology Letters 2017 22:8
  16. Pseudoxanthoma elasticum (PXE) is characterized by progressive ectopic mineralization of elastic fibers in dermal, ocular and vascular tissues. No effective treatment exists. It is caused by inactivating mutat...

    Authors: Rocchina Miglionico, Angela Ostuni, Maria Francesca Armentano, Luigi Milella, Elvira Crescenzi, Monica Carmosino and Faustino Bisaccia
    Citation: Cellular & Molecular Biology Letters 2017 22:7
  17. Although the 3T3-L1 preadipocyte cell line represents an informative model for in vitro adipogenesis research, primary cultured cells are often needed to understand particular human or animal metabolic phenotypes...

    Authors: Yong Pu and Almudena Veiga-Lopez
    Citation: Cellular & Molecular Biology Letters 2017 22:6
  18. Human Tenon’s fibroblasts (HTFs) play a crucial role in wound healing. They cause postoperative scarring of the filtering bleb and are thus responsible for trabeculectomy failure. This study aimed to find an e...

    Authors: Agata Przekora, Tomasz Zarnowski and Grazyna Ginalska
    Citation: Cellular & Molecular Biology Letters 2017 22:5
  19. Neuron-glial antigen 2 (NG2), also known as chondroitin sulphate proteoglycan 4 (CSPG4), is a surface type I transmembrane core proteoglycan that is crucially involved in cell survival, migration and angiogene...

    Authors: Emmanuel Ampofo, Beate M. Schmitt, Michael D. Menger and Matthias W. Laschke
    Citation: Cellular & Molecular Biology Letters 2017 22:4
  20. Atherosclerosis is a chronically inflammatory disease and one of the leading causes of deaths worldwide. Endothelial cell apoptosis plays a crucial role in its development. Several microRNAs (miRNAs) are repor...

    Authors: Ying Li, Chunyan Yang, Lili Zhang and Ping Yang
    Citation: Cellular & Molecular Biology Letters 2017 22:3
  21. PU box-binding protein (PU.1) is a master gene of hematopoietic lineage and an important specific transcription factor in osteoclast lineage. There is proof of its expression in adipose tissue, and it is known...

    Authors: ChongMei Ruan, Xiu Li, JunJie Hu, Yong Zhang and XingXu Zhao
    Citation: Cellular & Molecular Biology Letters 2017 22:2
  22. The harmful side effects of electroporation to cells due to local changes in pH, the appearance of toxic electrode products, temperature increase, and the heterogeneity of the electric field acting on cells in...

    Authors: Maciej Grys, Zbigniew Madeja and WÅ‚odzimierz Korohoda
    Citation: Cellular & Molecular Biology Letters 2017 22:1
  23. The ubiquitin–proteasome system (UPS) and autophagy are two distinct and interacting proteolytic systems. They play critical roles in cell survival under normal conditions and during stress. An increasing body...

    Authors: Wei Jing Liu, Lin Ye, Wei Fang Huang, Lin Jie Guo, Zi Gan Xu, Hong Luan Wu, Chen Yang and Hua Feng Liu
    Citation: Cellular & Molecular Biology Letters 2016 21:29
  24. Immunoglobulin G (IgG) has been implicated in the progression of various cancers. This study explored the role of IgG in the proliferation, apoptosis, cell cycle and in vitro invasive properties of LNCaP prost...

    Authors: Yawen Xu, Binshen Chen, Shaobo Zheng, Yong Wen, Abai Xu, Kai Xu, Bingkun Li and Chunxiao Liu
    Citation: Cellular & Molecular Biology Letters 2016 21:27
  25. Cytoglobin (CYGB), a member of the globin family, is thought to protect cells from reactive oxygen and nitrogen species and deal with hypoxic conditions and oxidative stress. However, its molecular mechanisms ...

    Authors: Xin Li, Shanshan Zou, Zhen Li, Gaotai Cai, Bohong Chen, Ping Wang and Wenqi Dong
    Citation: Cellular & Molecular Biology Letters 2016 21:25
  26. Synonymous or silent mutations are often overlooked in genetic analyses for disease-causing mutations unless they are directly associated with potential splicing defects. More recent studies, however, indicate...

    Authors: Rafal Bartoszewski, Jaroslaw Króliczewski, Arkadiusz Piotrowski, Anna Janaszak Jasiecka, Sylwia Bartoszewska, Briana Vecchio-Pagan, Lianwu Fu, Aleksandra Sobolewska, Sadis Matalon, Garry R. Cutting, Steven M. Rowe and James F. Collawn
    Citation: Cellular & Molecular Biology Letters 2016 21:23
  27. How nutrition and growth factor restriction due to serum depletion affect trophoblast function remains poorly understood. We performed a proteomic differential study of the effects of serum depletion on a firs...

    Authors: Susana Novoa-Herran, Adriana Umaña-Perez, Francesc Canals and Myriam Sanchez-Gomez
    Citation: Cellular & Molecular Biology Letters 2016 21:22
  28. Long non-coding RNAs (lncRNAs) play critical and complicated roles in the regulation of various biological processes, including chromatin modification, transcription and post-transcriptional processing. Intere...

    Authors: Jiachun Sun, Junqiang Yan, Xiaozhi Yuan, Ruina Yang, Tanyou Dan, Xinshuai Wang, Guoqiang Kong and Shegan Gao
    Citation: Cellular & Molecular Biology Letters 2016 21:21
  29. As a key subunit of the exocyst complex, Exo70 has highly conserved sequence and is widely found in yeast, mammals, and plants. In yeast, Exo70 mediates the process of exocytosis and promotes anchoring and int...

    Authors: Wenqing Ma, Yu Wang, Xiaomeng Yao, Zijian Xu, Liguo An and Miao Yin
    Citation: Cellular & Molecular Biology Letters 2016 21:20
  30. The aim of this study was to evaluate the influence of RGC-32 (response gene to complement 32) on cell cycle progression in renal tubular epithelial cell injury.

    Authors: Yun-lin Shen, Hua-jie Liu, Lei Sun, Xiao-ling Niu, Xin-yu Kuang, Ping Wang, Sheng Hao and Wen-yan Huang
    Citation: Cellular & Molecular Biology Letters 2016 21:19
  31. Bcl2-associated athanogene 2 (BAG2) shares a similar molecular structure and function with other BAG family members. Functioning as a co-chaperone, it interacts with the ATPase domain of the heat shock protein...

    Authors: Lixia Qin, Jifeng Guo, Qian Zheng and Hainan Zhang
    Citation: Cellular & Molecular Biology Letters 2016 21:18
  32. Understanding the cellular pathways that regulate endothelial nitric oxide (eNOS, NOS3) expression and consequently nitric oxide (NO) bioavailability during hypoxia is a necessary aspect in the development of nov...

    Authors: Leszek Kalinowski, Anna Janaszak-Jasiecka, Anna Siekierzycka, Sylwia Bartoszewska, Marcin Woźniak, Dawid Lejnowski, James F. Collawn and Rafal Bartoszewski
    Citation: Cellular & Molecular Biology Letters 2016 21:16
  33. Histone H1.0 belongs to the class of linker histones (H1), although it is substantially distinct from other histone H1 family members. The differences can be observed in the chromosomal location and organizati...

    Authors: Andrzej Kowalski
    Citation: Cellular & Molecular Biology Letters 2016 21:15
  34. In cartilage tissue regeneration, it is important to develop biodegradable scaffolds that provide a structural and logistic template for three-dimensional cultures of chondrocytes. In this study, we evaluated ...

    Authors: Piotr Paduszyński, Ewelina Aleksander-Konert, Alicja Zajdel, Adam Wilczok, Katarzyna Jelonek, Andrzej Witek and Zofia Dzierżewicz
    Citation: Cellular & Molecular Biology Letters 2016 21:14
  35. Osteoporosis, or bone loss, is a progressive, systemic skeletal disease that affects millions of people worldwide. Osteoporosis is generally age related, and it is underdiagnosed because it remains asymptomati...

    Authors: Jitrada Phetfong, Tanwarat Sanvoranart, Kuneerat Nartprayut, Natakarn Nimsanor, Kanokwan Seenprachawong, Virapong Prachayasittikul and Aungkura Supokawej
    Citation: Cellular & Molecular Biology Letters 2016 21:12
  36. In this study, we evaluated the usefulness of two commercially available hyaluronic acid-based hydrogels, HyStem and HyStem-C, for the cultivation of Wharton’s jelly mesenchymal stem cells (WJ-MSCs) and their ...

    Authors: Ewelina Aleksander-Konert, Piotr Paduszyński, Alicja Zajdel, Zofia Dzierżewicz and Adam Wilczok
    Citation: Cellular & Molecular Biology Letters 2016 21:11
  37. This study focused on an extract from fermented flour from the Lady Joy variety of the common bean Phaseolus vulgaris. The extract, Lady Joy lysate (Lys LJ), is enriched in antioxidant compounds during the fermen...

    Authors: Morena Gabriele, Laura Pucci, Margherita La Marca, Daniela Lucchesi, Clara Maria Della Croce, Vincenzo Longo and Valter Lubrano
    Citation: Cellular & Molecular Biology Letters 2016 21:10
  38. Wnt5A, which is a member of the non-transforming Wnt protein family, is implicated in inflammatory processes. It is also highly expressed by ovarian cancer cells. ROR2, which is a member of the Ror-family of r...

    Authors: Somayeh Arabzadeh, Ghamartaj Hossein, Zahra Salehi-Dulabi and Amir Hassan Zarnani
    Citation: Cellular & Molecular Biology Letters 2016 21:9
  39. Phosphorus is a poorly bioavailable macronutrient that is essential for crop growth and yield. Overuse of phosphorus fertilizers results in low phosphorus use efficiency (PUE), has serious environmental conseq...

    Authors: Md. Mahmudul Hasan, Md. Mainul Hasan, Jaime A. Teixeira da Silva and Xuexian Li
    Citation: Cellular & Molecular Biology Letters 2016 21:7
  40. The prognosis for patients with esophageal cancer remains poor. Therefore, the identification of novel target molecules for the treatment of esophageal cancer is necessary. Here, we investigated the clinicopat...

    Authors: Hideyuki Ishiguro, Takehiro Wakasugi, Yukio Terashita, Nobuhiro Sakamoto, Tatsuya Tanaka, Hiroyuki Sagawa, Tomotaka Okubo and Hiromitsu Takeyama
    Citation: Cellular & Molecular Biology Letters 2016 21:5
  41. Adenosylcobalamin (vitamin B12) is a coenzyme required for the activity of methylmalonyl-CoA mutase. Defects in this enzyme are a cause of methylmalonic acidemia (MMA). Methylmalonic acidemia, cblA type, is an...

    Authors: Fatemeh Keyfi, Mohammad Reza Abbaszadegan, Arndt Rolfs, Slobodanka Orolicki, Morteza Moghaddassian and Abdolreza Varasteh
    Citation: Cellular & Molecular Biology Letters 2016 21:4
  42. miR-126 is a key regulator of oncogenic processes. It is functionally linked to cellular proliferation, survival and migration. Vascular endothelial growth factor A (VEGF-A), which is regarded as a tumorgenesi...

    Authors: Ranran Kong, Yuefeng Ma, Jie Feng, Shaomin Li, Wei Zhang, Jiantao Jiang, Jin Zhang, Zhe Qiao, Xiaoping Yang and Bin Zhou
    Citation: Cellular & Molecular Biology Letters 2016 21:3
  43. Innate immunity plays a crucial role in the pathogenesis of type 2 diabetes and related complications. Since the toll-like receptors (TLRs) are central to innate immunity, it appears that they are important pa...

    Authors: Zahra Sepehri, Zohre Kiani, Ali Akbar Nasiri and Farhad Kohan
    Citation: Cellular & Molecular Biology Letters 2016 21:2

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