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  1. Hybrid cells derived from stem cells play an important role in organogenesis, tissue regeneration and cancer formation. However, the fate of hybrid cells and their range of function are poorly understood. Fusi...

    Authors: Dan Xu, Feng Wang, Hongyan Gu, Jia Wang, Qinglong Guo, Yanli Zhang and Ziyu Wang
    Citation: Cellular & Molecular Biology Letters 2010 15:18
  2. Cisplatin and doxorubicin are widely used anticancer drugs that cause DNA damage, which activates the ATM-Chk2-p53 pathway in cancer cells. This activation leads to cell cycle block or apoptosis, depending on ...

    Authors: Pavla Hublarova, Kristina Greplova, Jitka Holcakova, Borivoj Vojtesek and Roman Hrstka
    Citation: Cellular & Molecular Biology Letters 2010 15:21
  3. Heterogeneous human amniotic fluid contains various cell types. Herein, we report on the possibility of simultaneously isolating three subtypes of cells from one primary culture. Using a stainless steel instru...

    Authors: Shengli Zhang, Hongquan Geng, Hua Xie, Qiquan Wu, Xiaorong Ma, Junmei Zhou and Fang Chen
    Citation: Cellular & Molecular Biology Letters 2010 15:17
  4. Calpains and caspases are ubiquitous cysteine proteases that are associated with a variety of cellular pathways. Calpains are involved in processes such as long term potentiation, cell motility and apoptosis, ...

    Authors: Ramunas Rolius, Chloe Antoniou, Lidia A. Nazarova, Stephen H. Kim, Garrett Cobb, Pooja Gala, Priyanka Rajaram, Qufei Li and Leslie W.-M. Fung
    Citation: Cellular & Molecular Biology Letters 2010 15:15
  5. The PKB signaling pathway is essential for cell survival and the inhibition of apoptosis, but its functional mechanisms have not been fully explored. Previously, we reported that TPA effectively inhibited PKB ...

    Authors: Bing Zhang and Chun Xia
    Citation: Cellular & Molecular Biology Letters 2010 15:14
  6. The mechanism by which the mitochondrial large rRNA is involved in the restoration of the pole cell-forming ability in Drosophila embryos is still unknown. We identified a 15-ribonucleotide sequence which is cons...

    Authors: Rossana Psaila, Donatella Ponti, Marta Ponzi, Franca Gigliani and Piero Augusto Battaglia
    Citation: Cellular & Molecular Biology Letters 2010 15:13
  7. It was previously shown that the beta-spectrin ankyrin-binding domain binds lipid domains rich in PE in an ankyrin-dependent manner, and that its N-terminal sequence is crucial in interactions with phospholipi...

    Authors: Anna Chorzalska, Agnieszka Łach, Tomasz Borowik, Marcin Wolny, Anita Hryniewicz-Jankowska, Adam Kolondra, Marek Langner and Aleksander F. Sikorski
    Citation: Cellular & Molecular Biology Letters 2010 15:12
  8. Many studies have implicated cell-surface lectins in heterologous cell-cell adhesion, but little is known about the participation of lectins in cellular adhesion in homologous cells. Here, we show the developm...

    Authors: Saswati Banerjee and Gopal Chandra Majumder
    Citation: Cellular & Molecular Biology Letters 2010 15:11
  9. Lifeguard (LFG) is an anti-apoptotic protein that inhibits Fas-mediated death in tumour cells. However, the molecular function of human LFG in the carcinogenesis of human breast cells is uncertain. We studied ...

    Authors: Vesna Bucan, Kerstin Reimers, Claudia Yu Choi, Mau-Thek Eddy and Peter M. Vogt
    Citation: Cellular & Molecular Biology Letters 2010 15:9
  10. ZBTB7A is a known proto-oncogene that is implicated in carcinogenesis and cell differentiation and development. Fully understanding the function of ZBTB7A in cellular processes could provide useful strategies ...

    Authors: Xuyu Zu, Lingling Yu, Yiming Sun, Jing Tian, Feng Liu, Qinsheng Sun, Shengnan He, Guang Sun, Weishi Luo and Yuyang Jiang
    Citation: Cellular & Molecular Biology Letters 2010 15:3
  11. Cutaneous T-cell lymphomas (CTCLs) are non-Hodgkin’s lymphomas resulting from clonal expansion and localization of malignant T-lymphocytes to the skin. CTCL cells have defective apoptosis. Signal transducers a...

    Authors: Navin K. Verma, Anthony M. Davies, Aideen Long, Dermot Kelleher and Yuri Volkov
    Citation: Cellular & Molecular Biology Letters 2010 15:8
  12. Id1 (inhibitor of differentiation 1) is a member of the bHLH protein family. Consistent with its role in promoting proliferation and inhibiting differentiation, Id1 expression is low or negligible in normal pr...

    Authors: Michelle Schmidt, Ananthi J. Asirvatham and Jaideep Chaudhary
    Citation: Cellular & Molecular Biology Letters 2010 15:7
  13. The discovery of circulating nucleic acids in the 1940s opened up new possibilities for the non-invasive detection, monitoring and screening of various human disorders. Several tumour markers that enable early...

    Authors: Marketa Urbanova, Jan Plzak, Hynek Strnad and Jan Betka
    Citation: Cellular & Molecular Biology Letters 2010 15:4
  14. There is a growing interest in dietary therapeutic strategies to combat oxidative stress-induced damage to the Central Nervous System (CNS), which is associated with a number of pathophysiological processes, i...

    Authors: Ana Faria, Diogo Pestana, Diana Teixeira, Joana Azevedo, Victor De Freitas, Nuno Mateus and Conceição Calhau
    Citation: Cellular & Molecular Biology Letters 2010 15:6
  15. We investigated the action of the quaternary ammonium salt (QAS) called IM (N-(dodecyloxycarboxymethyl)-N,N,N-trimethyl ammonium chloride) on Saccharomyces cerevisiae yeast cells. Changes in the yeast cell ultras...

    Authors: Ewa Obłąk, Andrzej Gamian, Ryszard Adamski and Stanisław Ułaszewski
    Citation: Cellular & Molecular Biology Letters 2010 15:2
  16. The main aims of this study were to determine the effects of GH gene abuse/misuse in normal animals and to discover genes that could be used as candidate biomarkers for the detection of GH gene therapy abuse/m...

    Authors: Ying Qin and Ya-Ping Tian
    Citation: Cellular & Molecular Biology Letters 2010 15:1
  17. Heterozygous missense mutations in IHH result in Brachydactyly type A1 (BDA1; OMIM 112500), a condition characterized by the shortening of digits due to hypoplasia/aplasia of the middle phalanx. Indian Hedgehog s...

    Authors: Shengzhen Guo, Jian Zhou, Bo Gao, Jianxin Hu, Hongsheng Wang, Junwei Meng, Xinzhi Zhao, Gang Ma, Chuwen Lin, Yue Xiao, Wei Tang, Xuming Zhu, Kathryn S.E. Cheah, Guoying Feng, Danny Chan and Lin He
    Citation: Cellular & Molecular Biology Letters 2009 15:40
  18. The dystrophin-glycoprotein complex (DGC) is a large trans-sarcolemmal complex that provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. In skeletal muscle, it consists of t...

    Authors: Stéphanie Daval, Chantal Rocher, Yan Cherel and Elisabeth Le Rumeur
    Citation: Cellular & Molecular Biology Letters 2009 15:134
  19. The telomere structures in Bombyx mori are thought to be maintained mainly by the transposition of the specialized telomeric retroelements SART and TRAS. The silkworm genome has telomeric TTAGG repeats and telome...

    Authors: Tsuneyuki Tatsuke, Kosuke Sakashita, Yuki Masaki, Jae Man Lee, Yutaka Kawaguchi and Takahiro Kusakabe
    Citation: Cellular & Molecular Biology Letters 2009 15:118
  20. Many of the effects of carnitine are ascribed to its antioxidant properties. The aim of this study was to evaluate the antioxidant properties of carnitine in vitro. Carnitine was found to decolorize ABTS•+, and t...

    Authors: Katarzyna Solarska, Anna Lewińska, Agata Karowicz-Bilińska and Grzegorz Bartosz
    Citation: Cellular & Molecular Biology Letters 2009 15:90
  21. In this paper, we present the results of a study on the membrane-active properties of gossypol, its derivatives and their polyvinylpyrrolidone complexes as assessed by differential scanning calorimetry and by ...

    Authors: Maksim Ionov, Ilnora Tukfatullina, Bakhtiyar Salakhutdinov, Nina Baram, Maria Bryszewska and Takhir Aripov
    Citation: Cellular & Molecular Biology Letters 2009 15:37
  22. The outer membrane proteins (OMPs) are the most immunogenic and attractive of the Moraxella catarrhalis vaccine antigens that may induce the protective immune response. The aim of this study was to determine the ...

    Authors: Daria Augustyniak, Józef Mleczko and Jan Gutowicz
    Citation: Cellular & Molecular Biology Letters 2009 15:70
  23. This study focused on establishing and making a comprehensive functional characterization of an HEK-293-transfected cell line that would coexpress the enhanced yellow fluorescent protein-actin (pEYFP-actin) co...

    Authors: Alenka Hrovat, Apolonija Bedina Zavec, Azra Pogačnik, Robert Frangež and Milka Vrecl
    Citation: Cellular & Molecular Biology Letters 2009 15:55
  24. hTERT (human telomerase reverse transcriptase) plays a key role in the process of cell immortalization. Overexpression of hTERT has been implicated in 85% of malignant tumors and offers a specific target for c...

    Authors: Xiangying Zhu, Nan Yang, Jianguo Cai, Guimei Yang, Shenghua Liang and Daming Ren
    Citation: Cellular & Molecular Biology Letters 2009 15:32
  25. Spectrin tetramerization is important for the erythrocyte to maintain its unique shape, elasticity and deformability. We used recombinant model proteins to show the importance of one residue (G46) in the eryth...

    Authors: Jianxia Kang, Yuanli Song, Akin Sevinc and Leslie W.-M. Fung
    Citation: Cellular & Molecular Biology Letters 2009 15:46
  26. Peptidylarginine deiminases (PADs) convert the arginine residues in proteins into citrulline residues in a Ca2+-dependent manner. We previously showed that a bilateral injection of ibotenic acid into the rat nucl...

    Authors: Mohammad Arif and Takeshi Kato
    Citation: Cellular & Molecular Biology Letters 2009 14:29
  27. Genetic manipulation of the filamentous fungus Penicillium camemberti has been limited by a lack of suitable genetics tools for this fungus. In particular, there is no available homologous transformation system. ...

    Authors: Katherinne Navarrete, Amanda Roa, Inmaculada Vaca, Yeison Espinosa, Claudio Navarro and Renato Chávez
    Citation: Cellular & Molecular Biology Letters 2009 14:28
  28. Malignant tumors are characterized by dysregulated cell growth and the metastasis of secondary tumors. Numerous studies have documented that osteopontin (OPN) plays a key role in regulating tumor progression a...

    Authors: Ya-Jun Liu, Dao-Qiang Zhang, Xiu-Mei Sui and Wei Tian
    Citation: Cellular & Molecular Biology Letters 2009 14:27
  29. Podocin (NPHS2) is a component of the glomerular slit membrane with major regulatory functions in the renal permeability of proteins. A loss of podocin and a decrease in its resynthesis can influence the outco...

    Authors: Sigrid Harendza, Rolf A.K. Stahl and André Schneider
    Citation: Cellular & Molecular Biology Letters 2009 14:26
  30. In this study, we evaluated the activities of new types of azaphenothiazines in the following immunological assays: the proliferative response of human peripheral blood mononuclear cells induced by phytohemagg...

    Authors: Michał Zimecki, Jolanta Artym, Maja Kocięba, Krystian Pluta, Beata Morak-Młodawska and Małgorzata Jeleń
    Citation: Cellular & Molecular Biology Letters 2009 14:25
  31. The human SFRS9/SRp30c belongs to the SR family of splicing regulators. Despite evidence that members of this protein family may be targeted by arginine methylation, this has yet to be experimentally addressed...

    Authors: Gustavo C. Bressan, Eduardo C. Moraes, Adriana O. Manfiolli, Tais M. Kuniyoshi, Dario O. Passos, Marcelo D. Gomes and Jörg Kobarg
    Citation: Cellular & Molecular Biology Letters 2009 14:24
  32. Dendritic cells (DC) are professional antigen-presenting cells capable of initiating primary immune responses. They have been intensively studied and are used in both basic immunology research and clinical imm...

    Authors: Weixue Zhong, Min Fei, Yibei Zhu and Xueguang Zhang
    Citation: Cellular & Molecular Biology Letters 2009 14:23
  33. The interleukin-12p40 gene (IL12B) encodes the p40 polypeptide chain, which, together with p19, composes IL-23. A bi-allelic promoter polymorphism (IL12Bpro) located at −2703 bp of the transcription initiation si...

    Authors: Zlatka Georgieva Dobreva, Spaska Angelova Stanilova and Lyuba Dineva Miteva
    Citation: Cellular & Molecular Biology Letters 2009 14:22
  34. Cells interact by exchanging material and information. Two methods of cell-to-cell communication are by means of microvesicles and by means of nanotubes. Both microvesicles and nanotubes derive from the cell m...

    Authors: Karin Schara, Vid Janša, Vid Šuštar, Drago Dolinar, Janez Ivan Pavlič, Maruša Lokar, Veronika Kralj-Iglič, Peter Veranič and Aleš Iglič
    Citation: Cellular & Molecular Biology Letters 2009 14:18
  35. Human serum albumin (HSA) inhibits endothelial apoptosis in a highly specific manner. CNBr fragmentation greatly increases the effectiveness of this activity, suggesting that this type of protection is mediate...

    Authors: Hans Zoellner, Salman Siddiqui, Elizabeth Kelly and Heather Medbury
    Citation: Cellular & Molecular Biology Letters 2009 14:21
  36. The mitogen-activated protein kinase (MAPK) cascades regulate important cellular processes, including growth, differentiation, apoptosis, embryogenesis, motility and gene expression. Although MAPKs mostly appe...

    Authors: Nancy Gerits, Alexey Shiryaev, Sergiy Kostenko, Helle Klenow, Olga Shiryaeva, Mona Johannessen and Ugo Moens
    Citation: Cellular & Molecular Biology Letters 2009 14:20
  37. CC chemokine receptor 5 (CCR5) is a pro-inflammatory chemokine receptor that is expressed on cells of the immune system, and specializes in cell migration in response to inflammation and tissue damage. Due to ...

    Authors: Debra L. Kiss, James Longden, Gregory A. Fechner and Vicky M. Avery
    Citation: Cellular & Molecular Biology Letters 2009 14:17
  38. Mesenchymal stem cells (MSCs) constitute an interesting cellular source to promote brain regeneration after Parkinson’s disease. MSCs have significant advantages over other stem cell types, and greater potenti...

    Authors: Li Chen, Dong-Mei He and Yuan Zhang
    Citation: Cellular & Molecular Biology Letters 2009 14:15
  39. Although genetic factors are a well-known cause of colorectal cancer, environmental factors contribute more to its development. Despite advances in the fields of surgery, radiotherapy and chemotherapy, the cur...

    Authors: Kyung Min Yang, Jong Ok Pyo, Gyu-Yeol Kim, Rina Yu, In Seob Han, Seong A. Ju, Won Ho Kim and Byung-Sam Kim
    Citation: Cellular & Molecular Biology Letters 2009 14:16
  40. The tissue-specific expressions of creatine kinase (CK) isoforms are regulated by the coordinated action of various transcription factors. The myogenic differentiation factor D (MyoD) family of proteins and th...

    Authors: Soumen Bera and Manju Ray
    Citation: Cellular & Molecular Biology Letters 2009 14:14
  41. Biot2 is a novel murine testis-specific gene that was first identified using the SEREX technique, and named by our laboratory. Using conventional RT-PCR and real time RT-PCR, we tested the expression profile o...

    Authors: Chun-Ting Wang, Peng Zhang, Yong-Sheng Wang, Xu-Zhi Ruan, Zhi-Yong Li, Feng Peng, Han-Shuo Yang and Yu-Quan Wei
    Citation: Cellular & Molecular Biology Letters 2009 14:4
  42. Protein kinase B (PKB/Akt) is a serine-threonine kinase functioning downstream of phosphatidylinositol 3-kinase (PI-3 kinase) in response to mitogen or growth factor stimulation. In several cell types, it play...

    Authors: Bing Zhang and Chun Xia
    Citation: Cellular & Molecular Biology Letters 2009 14:13
  43. Recent reports have indicated that, as well as having antiresorptive effects, bisphosphonates could have an application as anti-inflammatory drugs. Our aim was to investigate whether this anti-inflammatory act...

    Authors: Eleonora Salvolini, Monia Orciani, Arianna Vignini, Roberto Di Primio and Laura Mazzanti
    Citation: Cellular & Molecular Biology Letters 2009 14:12
  44. Several studies have reported different expression levels of certain genes in NSCLC, mostly related to the stage and advancement of the tumours. We investigated 65 stage I-III NSCLC tumours: 32 adenocarcinomas...

    Authors: Mojca Stražišar, Vid Mlakar and Damjan Glavač
    Citation: Cellular & Molecular Biology Letters 2009 14:11
  45. Sphingosine kinase-1 (SK1) promotes the formation of sphingosine-1-phosphate (S1P), which has potent pro-inflammatory and pro-angiogenic effects. We investigated the effects of raised SK1 levels on endothelial...

    Authors: Vidya Limaye, Pu Xia, Chris Hahn, Malcolm Smith, Mathew A. Vadas, Stuart M. Pitson and Jennifer R. Gamble
    Citation: Cellular & Molecular Biology Letters 2009 14:9
  46. The enzyme sphingosine kinase-1 (SK1) promotes the formation of sphingosine-1-phosphate (S1P), which is an important survival factor for endothelial cells (EC). Modest increases in intracellular SK1 activity i...

    Authors: Vidya Limaye, Mathew A. Vadas, Stuart M. Pitson and Jennifer R. Gamble
    Citation: Cellular & Molecular Biology Letters 2009 14:8
  47. A protocol for the induction of regeneration from leaves of Helichrysum italicum was established. Calli were found to form on the basal medium only when it was supplemented with thidiazuron (TDZ) alone or in comb...

    Authors: Rosaria Perrini, Vittorio Alba, Claudia Ruta, Irene Morone-Fortunato, Antonio Blanco and Cinzia Montemurro
    Citation: Cellular & Molecular Biology Letters 2009 14:7

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