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  1. Proteins are responsible for all biological activities in living organisms. Thanks to genome sequencing projects, large amounts of DNA and protein sequence data are now available, but the biological functions ...

    Authors: Sovan Saha, Piyali Chatterjee, Subhadip Basu, Mahantapas Kundu and Mita Nasipuri
    Citation: Cellular & Molecular Biology Letters 2014 19:221
  2. We aim to demonstrate the role of Alk receptors in the response of hydrogel expansion. Chondrocytes from rat knees were cultured onto plastic and hydrogel surfaces. Alk-1 and Alk-5 were overexpressed or silenc...

    Authors: Patricia Sanz-Ramos, Javier Dotor and Iñigo Izal-Azcárate
    Citation: Cellular & Molecular Biology Letters 2014 19:220
  3. Peripheral T cells are in G0 phase and do not proliferate. When they encounter an antigen, they enter the cell cycle and proliferate in order to initiate an active immune response. Here, we have determined the...

    Authors: Takuya Mishima, Shoko Toda, Yoshiaki Ando, Tsukasa Matsunaga and Manabu Inobe
    Citation: Cellular & Molecular Biology Letters 2014 19:219
  4. Phosphoantigens (PAgs) activate Vγ9Vδ2 T lymphocytes, inducing their potent and rapid response in vitro and in vivo. However, humans and nonhuman primates that receive repeated injections of PAgs progressively...

    Authors: Mary Poupot, Frédéric Boissard, Delphine Betous, Laure Bardouillet, Séverine Fruchon, Fatima L’Faqihi-Olive, Frédéric Pont, Mourad Mekaouche, Sophie Ingoure, Hélène Sicard, Guy Dubreuilh and Jean-Jacques Fournié
    Citation: Cellular & Molecular Biology Letters 2014 19:218
  5. CD14 plays a crucial role in the inflammatory response to lipopolysaccharide (LPS), which interacts with TLR4 and MD-2 to enable cell activation, resulting in inflammation. Upstream inhibition of the inflammat...

    Authors: Xiangping Li, Meiqing Li, Shihai Huang, Shuye Qiao, Zhaoxian Qin, Chao Kang and Deshun Shi
    Citation: Cellular & Molecular Biology Letters 2014 19:217
  6. Reactive oxygen species (ROS) have been proven to be important activators for various cellular activities, including cell differentiation. Several reports showed the necessity of ROS during cell differentiatio...

    Authors: Retno Wahyu Nurhayati, Yoshihiro Ojima, Naoki Nomura and Masahito Taya
    Citation: Cellular & Molecular Biology Letters 2014 19:215
  7. The interstitial cells of Cajal (ICC) drive the slow wave-associated contractions in the small intestine. A commonly used marker for these cells is c-Kit, but another marker named Ano1 was recently described. Thi...

    Authors: Raúl Loera-Valencia, Xuan-Yu Wang, George W. J. Wright, Carlos Barajas-López and Jan D. Huizinga
    Citation: Cellular & Molecular Biology Letters 2014 19:214
  8. Enoyl coenzyme A hydratase short chain 1 (ECHS1) is an important part of the mitochondrial fatty acid β-oxidation pathway. Altered ECHS1 expression has been implicated in cancer cell proliferation. This study ...

    Authors: Xiao-San Zhu, Peng Gao, Yi-Chen Dai, Jun-Pei Xie, Wei Zeng and Qing-Na Lian
    Citation: Cellular & Molecular Biology Letters 2014 19:213
  9. Long non-coding RNAs (lncRNAs) are series of transcripts with important biological functions. Various diseases have been associated with aberrant expression of lncRNAs and the related dysregulation of mRNAs. I...

    Authors: Zhuomin Wu, Xiaoxia Liu, Li Liu, Houliang Deng, Jingjing Zhang, Qian Xu, Bohong Cen and Aimin Ji
    Citation: Cellular & Molecular Biology Letters 2014 19:212
  10. The study aimed to assess biophysical changes that take place in the peripheral blood mononuclear cell (PBMC) membranes when exposed in vitro to 10 μM quercetin or epigallocatechin gallate (EGCG) for 24 and 48...

    Authors: Denisa Margina, Mihaela Ilie, Gina Manda, Ionela Neagoe, Rucsandra Danciulescu-Miulescu, Carmen Nicoleta Purdel and Daniela Gradinaru
    Citation: Cellular & Molecular Biology Letters 2014 19:211
  11. Angiogenesis plays a crucial role in the growth, invasion and metastasis of breast cancer. Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are the key regulators of tumor angiogenesis....

    Authors: Xiao Zhang, Yin-Lin Ge, Shu-Ping Zhang, Ping Yan and Run-Hua Tian
    Citation: Cellular & Molecular Biology Letters 2014 19:210
  12. Resveratrol is the most extensively studied stilbene derivative. We previously showed that methylthiostilbenes were more effective inhibitors of CYP1A1 and 1B1 activity than resveratrol. In this study, we inve...

    Authors: Violetta Krajka-Kuźniak, Hanna Szaefer, Tomasz Stefański, Stanisław Sobiak, Michał Cichocki and Wanda Baer-Dubowska
    Citation: Cellular & Molecular Biology Letters 2014 19:209
  13. ABCC6 protein is an ATP-dependent transporter that is mainly found in the basolateral plasma membrane of hepatocytes. ABCC6 deficiency is the primary cause of several forms of ectopic mineralization syndrome. ...

    Authors: Rocchina Miglionico, Maria Francesca Armentano, Monica Carmosino, Antonella Maria Salvia, Flavia Cuviello, Faustino Bisaccia and Angela Ostuni
    Citation: Cellular & Molecular Biology Letters 2014 19:208
  14. This paper focuses on the development of renewable sources of isletreplacement tissue for the treatment of type I diabetes mellitus. Placental tissue-derived mesenchymal stem cells (MSCs) are a promising sourc...

    Authors: Anahita Shaer, Negar Azarpira, Akbar Vahdati, Mohammad Hosein Karimi and Mehrdad Shariati
    Citation: Cellular & Molecular Biology Letters 2014 19:207
  15. Unlike nuclear nucleolin, surface-expressed and cytoplasmic nucleolin exhibit Tn antigen. Here, we show localization-dependent differences in the glycosylation and proteolysis patterns of nucleolin. Our result...

    Authors: Dorota Hoja-Łukowicz, Sylwia Kedracka-Krok, Weronika Duda and Anna Lityńska
    Citation: Cellular & Molecular Biology Letters 2014 19:206
  16. Protein glycation is initiated by a nucleophilic addition reaction between the free amino group from a protein, lipid or nucleic acid and the carbonyl group of a reducing sugar. This reaction forms a reversibl...

    Authors: Parveen Salahuddin, Gulam Rabbani and Rizwan Hasan Khan
    Citation: Cellular & Molecular Biology Letters 2014 19:205
  17. There is no doubt that cancer is not only a genetic disease but that it can also occur due to epigenetic abnormalities. Diet and environmental factors can alter the scope of epigenetic regulation. The results ...

    Authors: Ewa Forma, Paweł Jóźwiak, Magdalena Bryś and Anna Krześlak
    Citation: Cellular & Molecular Biology Letters 2014 19:204
  18. Many experimental studies have demonstrated the favorable biological activities of plants belonging to the genus Rubus, but little is known of the role of Rubus leaf extracts in the modulation of the surface memb...

    Authors: Dominika Dudzinska, Boguslawa Luzak, Magdalena Boncler, Joanna Rywaniak, Dorota Sosnowska, Anna Podsedek and Cezary Watala
    Citation: Cellular & Molecular Biology Letters 2014 19:202
  19. The large microtubule-associated/Ca2+-signalling protein p600 (also known as UBR4) is required for hippocampal neuronal survival upon Ca2+ dyshomeostasis induced by glutamate treatment. During this process, p600 ...

    Authors: Camille Belzil, Tim Ramos, Kamon Sanada, Michael A. Colicos and Minh Dang Nguyen
    Citation: Cellular & Molecular Biology Letters 2014 19:201
  20. Erythropoietin (EPO) has a beneficial effect on hepatic cell proliferation during liver regeneration. However, the underlying mechanism has not yet been elucidated. To uncover the proliferation response of EPO...

    Authors: Jihong Zhang, Yajuan Yang, Tingting He, Yunqing Liu, Yun Zhou, Yongkang Chen and Cunshuan Xu
    Citation: Cellular & Molecular Biology Letters 2014 19:198
  21. Epithelial-mesenchymal transition (EMT) of peritoneal mesothelial cells (PMC) is a major contributor to the pathogenesis of peritoneal fibrosis. EMT is at least in part caused by repeated exposure to glucose d...

    Authors: Hong Liu, Ning Zhang and Da Tian
    Citation: Cellular & Molecular Biology Letters 2014 19:199
  22. Degradable aliphatic polyesters such as polylactides, polyglycolides and their copolymers are used in several biomedical and pharmaceutical applications. We analyzed the influence of poly(L-lactide-co-glycolid...

    Authors: Aleksandra Zuber, Julia Borowczyk, Eliza Zimolag, Malgorzata Krok, Zbigniew Madeja, Elzbieta Pamula and Justyna Drukala
    Citation: Cellular & Molecular Biology Letters 2014 19:197
  23. The aim of this study was to evaluate the immunoregulatory effects of recombinant human lactoferrin (rhLF) in two in vitro models: (1) the secondary humoral immune response to sheep erythrocytes (SRBC); and (2...

    Authors: Michał Zimecki, Jolanta Artym, Maja Kocięba, Maria Duk and Marian L. Kruzel
    Citation: Cellular & Molecular Biology Letters 2014 19:196
  24. This study aims to describe the hemoglobin Fannin-Lubbock-I, which has a rare mutation substituting the amino acid glycine with aspartic acid at codon 119 of the β-globin chain. A Bengalee Hindu Brahmin family...

    Authors: Jayasri Basak, Deboshree M. Bhattacharyya and Ashis Mukhopadhyay
    Citation: Cellular & Molecular Biology Letters 2014 19:192
  25. The styryl dye FM1-43 becomes highly fluorescent upon binding to cell membranes. The breakdown of membrane phospholipid asymmetry in ionophore-stimulated T-lymphocytes further increases this fluorescence [Zwei...

    Authors: Anna Wróbel, Małgorzata Bobrowska-Hägerstrand, Christer Lindqvist and Henry Hägerstrand
    Citation: Cellular & Molecular Biology Letters 2014 19:195
  26. CA-125 (coelomic epithelium-related antigen) forms the extracellular portion of transmembrane mucin 16 (MUC16). It is shed after proteolytic degradation. Due to structural heterogeneity, CA-125 ligand capacity...

    Authors: Ninoslav Mitić, Bojana Milutinović and Miroslava Janković
    Citation: Cellular & Molecular Biology Letters 2014 19:194
  27. We used complexes between a fourth generation polyamidoamine (PAMAM) dendrimer and one of two heterocyclic compounds — 1-(6-hydroxyhexyl)-3-(5-phenyl-isoxazole-3-yl)-urea or 5-phenyl-isoxazole-3-carboxylic aci...

    Authors: Vladimir I. Potkin, Dzmitry Shcharbin, Andrey A. Denisov, Svetlana G. Paschkevich, Maria Bryszewska, Sergey K. Petkevich, Alexey V. Kletskov, Dmitri O. Lapotko, Vladimir V. Kazbanov, Tatiana A. Gurinovich and Vladimir A. Kulchitsky
    Citation: Cellular & Molecular Biology Letters 2014 19:193
  28. Radiotherapy and chemotherapeutic agents that damage DNA are the current major non-surgical means of treating cancer. However, many patients develop resistances to chemotherapy drugs in their later lives. The ...

    Authors: Ziwen Wang, Yujung Huang and Jiqiang Zhang
    Citation: Cellular & Molecular Biology Letters 2014 19:191
  29. 3-Bromopyruvic acid (3-BP) is a promising anticancer compound because it is a strong inhibitor of glycolytic enzymes, especially glyceraldehyde 3-phosphate dehydrogenase. The Warburg effect means that malignan...

    Authors: Izabela Sadowska-Bartosz, Mirosław Soszyński, Stanisław Ułaszewski, Young Ko and Grzegorz Bartosz
    Citation: Cellular & Molecular Biology Letters 2014 19:189
  30. Under normal physiological conditions, the majority of hepatocytes are in the functional state (G0 phase). After injury or liver partial hepatectomy (PH), hepatocytes are rapidly activated to divide. To unders...

    Authors: Menghua Li, Xiaochun Zhou, Jinxin Mei, Xiaofang Geng, Yun Zhou, Weimin Zhang and Cunshuan Xu
    Citation: Cellular & Molecular Biology Letters 2014 19:188
  31. Mesenchymal stem cells (MSCs) have both multi-lineage differentiation potential and immunosuppressive properties, making them ideal candidates for regenerative medicine. However, their immunosuppressive proper...

    Authors: Quansheng Li, Ping Yu, Wei Wang, Peng Zhang, Haiqing Yang, Shengfu Li and Li Zhang
    Citation: Cellular & Molecular Biology Letters 2014 19:187
  32. Periodontitis is an infectious disease caused by microorganisms present in dental bacterial plaque. Lipoteichoic acid (LTA) is a component of the external membrane of Gram-positive bacteria. It causes septic s...

    Authors: Gloria Gutiérrez-Venegas, Oscar Alonso Luna, Juan Antonio Arreguín-Cano and Cristina Hernández-Bermúdez
    Citation: Cellular & Molecular Biology Letters 2014 19:186
  33. The spectrin-based membrane skeleton is crucial for the mechanical stability and resilience of erythrocytes. It mainly contributes to membrane integrity, protein organization and trafficking. Two transmembrane...

    Authors: Dżamila M. Bogusławska, Beata Machnicka, Anita Hryniewicz-Jankowska and Aleksander Czogalla
    Citation: Cellular & Molecular Biology Letters 2014 19:185
  34. Cancer is the second leading cause of death in South Africa. The critical role that microtubules play in cell division makes them an ideal target for the development of chemotherapeutic drugs that prevent the ...

    Authors: Elize Wolmarans, Thandi V. Mqoco, Andre Stander, Sandra D. Nkandeu, Katherine Sippel, Robert McKenna and Annie Joubert
    Citation: Cellular & Molecular Biology Letters 2014 19:183
  35. Two isoforms of the erythrocyte histone H1.a were identified in two conservative flocks of Rhode Island Red chickens and six conservative flocks of ducks. The H1.a1 and H1.a2 isoforms formed three phenotypes (...

    Authors: Ewa Górnicka-Michalska, Andrzej Kowalski and Jan Pałyga
    Citation: Cellular & Molecular Biology Letters 2014 19:182
  36. Cellular adhesion to the underlying substratum is regulated through numerous signaling pathways. It has been suggested that insulin receptor substrate 1 (IRS-1) is involved in some of these pathways, via assoc...

    Authors: Arthur Czarnowski, Sylvia Papp, Peter Szaraz and Michal Opas
    Citation: Cellular & Molecular Biology Letters 2014 19:181
  37. MicroRNAs (miRNAs) regulate gene expression by inhibiting translation or targeting messenger RNA (mRNA) for degradation in a posttranscriptional fashion. In this study, we show that ectopic expression of miR-3...

    Authors: Qiu Chen, Lei Li, Yu Tu, Lu Lin Zheng, Wei Liu, Xue Yong Zuo, Yong Ming He, Shu Yu Zhang, Wei Zhu, Jian Ping Cao, Feng Mei Cui and Jun Hou
    Citation: Cellular & Molecular Biology Letters 2014 19:115
  38. The recently described method of cell electroporation by flow of cell suspension through localized direct current electric fields (dcEFs) was applied to identify non-toxic substances that could sensitize cells...

    Authors: Maciej Grys, Zbigniew Madeja and Włodzimierz Korohoda
    Citation: Cellular & Molecular Biology Letters 2014 19:114
  39. The influence of p53 status on potentially lethal damage repair (PLDR) and DNA double-strand break (DSB) repair was studied in two isogenic human colorectal carcinoma cell lines: RKO (p53 wild-type) and RC10.1...

    Authors: Bregje Van Oorschot, Arlene L. Oei, Anna C. Nuijens, Hans Rodermond, Ron Hoeben, Jan Stap, Lukas J. Stalpers and Nicolaas A. P. Franken
    Citation: Cellular & Molecular Biology Letters 2013 19:113
  40. Cancer stem cells (CSCs) are subpopulations of tumor cells that are responsible for tumor initiation, maintenance and metastasis. Recent studies suggested that lung cancer arises from CSCs. In this study, the ...

    Authors: Raheleh Roudi, Zahra Madjd, Marzieh Ebrahimi, Fazel Sahraneshin Samani and Ali Samadikuchaksaraei
    Citation: Cellular & Molecular Biology Letters 2013 19:112
  41. Pleiotropic drug resistance is a complex phenomenon that involves many proteins that together create a network. One of the common mechanisms of multidrug resistance in eukaryotic cells is the active efflux of ...

    Authors: Agata Piecuch and Ewa Obłąk
    Citation: Cellular & Molecular Biology Letters 2013 19:111
  42. Hereditary breast cancer constitutes 5–10% of all breast cancer cases. Inherited mutations in the BRCA1 and BRCA2 tumor-suppressor genes account for the majority of hereditary breast cancer cases. The BRCA1 C-...

    Authors: Abhijit Chakraborty, Atul Katarkar, Keya Chaudhuri, Ashis Mukhopadhyay and Jayasri Basak
    Citation: Cellular & Molecular Biology Letters 2013 18:110

    The Erratum to this article has been published in Cellular & Molecular Biology Letters 2014 19:s11658-014-0184-6

  43. Lamin A/C (LMNA), lamin B1 (LMNB1) and lamin B receptor (LBR) have key roles in nuclear structural integrity and chromosomal stability. In this study, we have studied the relationships between the mRNA express...

    Authors: Umar Wazir, Mai Hassan Ahmed, Joanna M. Bridger, Amanda Harvey, Wen G. Jiang, Anup K. Sharma and Kefah Mokbel
    Citation: Cellular & Molecular Biology Letters 2013 18:109
  44. Chlamydia trachomatis is a bacterial pathogen responsible for one of the most prevalent sexually transmitted infections worldwide. Its unique development cycle has limited our understanding of it...

    Authors: James W. Marsh, William B. Lott, Joel D. A. Tyndall and Wilhelmina Willa M. Huston
    Citation: Cellular & Molecular Biology Letters 2013 18:103

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