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Featured article: Emerging roles of prominin-1 (CD133) in the dynamics of plasma membrane architecture and cell signaling pathways in health and disease

CD133 is known for its association with stem cells and cancer stem cells, often used for their isolation. Recent research has revealed CD133's involvement in plasma membrane structures like microvilli and cilia, as well as in extracellular vesicle release and signaling pathways. This Review aims to summarize early studies on CD133 and present recent evidence of its involvement in membrane dynamics and molecular signaling, providing insights into its function in both health and disease.

Submission Guidance

As guidance on submissions does change over time, particularly relating to expectations that authors provide original images/blots and considerations for non-coding RNA papers, we ask that authors please ensure they read and comply with the guidance in the author guidelines which they can find here. Please note instructions may vary slightly by article type. Failure to comply with this guidance could result in delays in processing manuscripts.

Call For Papers

CMBL is currently commissioning a new special collection on Gene Regulation Tools for Treating Genetic Diseases and Cancers Based on CRISPR-related technologies. Guest Edited by Yuchen Liu, we welcome the submission of reviews and primary research articles that examine CRISPR-related technologies which have emerged as powerful tools for editing and manipulating genes, and have revolutionized the field of gene therapy. This Collection aims to highlight the latest research and developments in this field, with a focus on the regulatory tools used to treat genetic diseases and cancers.

Submission Deadline: July 31, 2024

Aims and scope

Cellular & Molecular Biology Letters is an international journal dedicated to the dissemination of fundamental knowledge in all areas of cellular and molecular biology, cancer cell biology, and certain aspects of biochemistry, biophysics and biotechnology.

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Aleksander Sikorski, University of Wrocław, Poland

Archival content

Cellular & Molecular Biology Letters was founded in 1996 and transferred to BioMed Central in 2016. Previously, its publishers were Walter De Gruyter in 2015 (content available from De Gruyter's archive), and Springer from 2006–2014 (content available from BMC web page). Articles published between 1996 and 2005 can be found at the CMBL home page, on the Volume List tab. To request free electronic versions of these articles, please contact

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Annual Journal Metrics

  • 2022 Citation Impact
    8.3 - 2-year Impact Factor
    7.2 - 5-year Impact Factor
    1.573 - SNIP (Source Normalized Impact per Paper)
    1.643 - SJR (SCImago Journal Rank)

    2023 Speed
    11 days submission to first editorial decision for all manuscripts (Median)
    105 days submission to accept (Median)

    2023 Usage 
    1,059 Altmetric mentions