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  1. An increasing number of studies have demonstrated the association of circular RNAs (circRNAs) with the pathological processes of various diseases and their involvement in the onset and progression of multiple ...

    Authors: Shuo Ma, Yanhua Xu, Xinyue Qin, Mei Tao, Xinliang Gu, Lei Shen, Yinhao Chen, Ming Zheng, Shiyi Qin, Guoqiu Wu and Shaoqing Ju
    Citation: Cellular & Molecular Biology Letters 2024 29:95
  2. We have previously identified an unsuspected role for GJB3 showing that the deficiency of this connexin protein induces aneuploidy in human and murine cells and accelerates cell transformation as well as tumor...

    Authors: Junnan Liu, Xue Wang, Wencheng Jiang, Anca Azoitei, Tim Eiseler, Markus Eckstein, Arndt Hartmann, Stephan Stilgenbauer, Mohamed Elati, Meike Hohwieler, Alexander Kleger, Axel John, Felix Wezel, Friedemann Zengerling, Christian Bolenz and Cagatay Günes
    Citation: Cellular & Molecular Biology Letters 2024 29:94
  3. Anti-angiogenic therapy has become one of the effective treatment methods for tumors. Long noncoding RNAs (lncRNAs) are emerging as important regulators of tumorigenesis and angiogenesis in EC. However, the un...

    Authors: Hanbo Ma, Fengyun Weng, Xiaowen Tong, Huaifang Li, Yinan Yao and Jiangjing Yuan
    Citation: Cellular & Molecular Biology Letters 2024 29:93
  4. Nasopharyngeal carcinoma (NPC), primarily found in the southern region of China, is a malignant tumor known for its highly metastatic characteristics. The high mortality rates caused by the distant metastasis ...

    Authors: Yao Wu, Qunying Jia, Qi Tang, Lin Chen, Hongyu Deng, Yingchun He and Faqing Tang
    Citation: Cellular & Molecular Biology Letters 2024 29:92
  5. The membrane-delimited receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), angiotensin-converting enzyme 2 (ACE2), which is expressed in the intestine, collaborates with broad neutral am...

    Authors: Jinze Li, Yingli Yan, Yang Fu, Zhe Chen, Yongjie Yang, Yu Li, Jie Pan, Feiwu Li, Cuifang Zha, Kai Miao, Lukuyu Ben, Muhammad Kashif Saleemi, Yongwen Zhu, Hui Ye, Lin Yang and Wence Wang
    Citation: Cellular & Molecular Biology Letters 2024 29:90
  6. CircR-loop, a recently unearthed regulatory mechanism situated at the crossroads of circular RNA and DNA interactions, constitute a subset of R-loop. This circR-loop have emerged as a crucial player in pivotal...

    Authors: Xinming Su, Yaojie Feng, Ruixiu Chen and Shiwei Duan
    Citation: Cellular & Molecular Biology Letters 2024 29:89
  7. Osteoarthritis (OA) is the most common degenerative joint disorder that causes disability in aged individuals, caused by functional and structural alterations of the knee joint. To investigate whether metaboli...

    Authors: Rong He, Yuchi Wei, Zeyu Peng, Jie Yang, Zhenwei Zhou, Ailin Li, Yongji Wu, Mingyue Wang, Xiangyan Li, Daqing Zhao, Zhonghua Liu, Haisi Dong and Xiangyang Leng
    Citation: Cellular & Molecular Biology Letters 2024 29:88
  8. Alzheimer’s disease (AD) is a progressive neurodegenerative disease and apolipoprotein E (APOE) genotypes (APOE2, APOE3, and APOE4) show different AD susceptibility. Previous studies indicated that individuals...

    Authors: Zhiyuan Ning, Ying Liu, Mengyao Wan, You Zuo, Siqi Chen, Zhongshan Shi, Yongteng Xu, Honghong Li, Ho Ko, Jing Zhang, Songhua Xiao, Daji Guo and Yamei Tang
    Citation: Cellular & Molecular Biology Letters 2024 29:87
  9. Canine mammary tumors (CMTs) in intact female dogs provide a natural model for investigating metastatic human cancers. Our prior research identified elevated expression of Anterior Gradient 2 (AGR2), a protein...

    Authors: Stephen Hsien-Chi Yuan, Chih-Ching Wu, Yu-Chih Wang, Xiu-Ya Chan, Hao-Wei Chu, Youngsen Yang and Hao-Ping Liu
    Citation: Cellular & Molecular Biology Letters 2024 29:84
  10. Senecavirus A (SVA) caused porcine idiopathic vesicular disease (PIVD) showing worldwide spread with economic losses in swine industry. Although some progress has been made on host factors regulating the repli...

    Authors: Huizi Li, Tingting Zheng, Ming Chen, Xiaoling Lei, Shuo Li, Xijiao Chen, Shishi Wang and Zhangyong Ning
    Citation: Cellular & Molecular Biology Letters 2024 29:83
  11. Hepatic stellate cells (HSCs) play a crucial role in the development of fibrosis in non-alcoholic fatty liver disease (NAFLD). Small extracellular vesicles (sEV) act as mediators for intercellular information ...

    Authors: Shihui Li, Fuji Yang, Fang Cheng, Ling Zhu and Yongmin Yan
    Citation: Cellular & Molecular Biology Letters 2024 29:82
  12. Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Studies have indicated that immune dysfunction plays a central role in the pathogenesis of sepsis. D...

    Authors: Li-yu Zheng, Yu Duan, Peng-yi He, Meng-yao Wu, Shu-ting Wei, Xiao-hui Du, Ren-qi Yao and Yong-ming Yao
    Citation: Cellular & Molecular Biology Letters 2024 29:81
  13. Sodium-glucose transporter 2 (SGLT2) inhibitors (iSGLT2) are approved medications for type 2 diabetes. Recent studies indicate that iSGLT2 inhibit the growth of some cancer cells. However, the mechanism(s) rem...

    Authors: Camilla Anastasio, Isabella Donisi, Vitale Del Vecchio, Antonino Colloca, Luigi Mele, Celestino Sardu, Raffaele Marfella, Maria Luisa Balestrieri and Nunzia D’Onofrio
    Citation: Cellular & Molecular Biology Letters 2024 29:80
  14. Postoperative cognitive dysfunction (POCD) is a common complication after anesthesia/surgery, especially among elderly patients, and poses a significant threat to their postoperative quality of life and overal...

    Authors: Wei-Feng Wu, Chen Chen, Jia-Tao Lin, Xin-Hao Jiao, Wei Dong, Jie Wan, Qiang Liu, Yong-Kang Qiu, Ao Sun, Yi-Qi Liu, Chun-Hui Jin, He Huang, Hui Zheng, Cheng-Hua Zhou and Yu-Qing Wu
    Citation: Cellular & Molecular Biology Letters 2024 29:79
  15. Alternative splicing of pre-mRNAs is a fundamental step in RNA processing required for gene expression in most metazoans. Serine and arginine-rich proteins (SR proteins) comprise a family of multifunctional pr...

    Authors: Mingrong Bei and Jianzhen Xu
    Citation: Cellular & Molecular Biology Letters 2024 29:78
  16. Tumor-associated macrophages (TAMs) significantly influence the progression, metastasis, and recurrence of esophageal squamous cell carcinoma (ESCC). The aberrant expression of long noncoding RNAs (lncRNAs) in...

    Authors: Lijun Zhao, Gengchao Wang, Haonan Qi, Lili Yu, Huilong Yin, Ruili Sun, Hongfei Wang, Xiaofei Zhu and Angang Yang
    Citation: Cellular & Molecular Biology Letters 2024 29:77
  17. The role of the scavenger receptor CD36 in cell metabolism and the immune response has been investigated mainly in macrophages, dendritic cells, and T cells. However, its involvement in B cells has not been co...

    Authors: Chenfei He, Guoying Hua, Yong Liu and Shuijie Li
    Citation: Cellular & Molecular Biology Letters 2024 29:76
  18. Mechanical spinal cord injury (SCI) is a deteriorative neurological disorder, causing secondary neuroinflammation and neuropathy. ADAM8 is thought to be an extracellular metalloproteinase, which regulates prot...

    Authors: Zhanyang Qian, Rulin Li, Tianyu Zhao, Kunxin Xie, PengFei Li, Guangshen Li, Na Shen, Jiamin Gong, Xin Hong, Lei Yang and Haijun Li
    Citation: Cellular & Molecular Biology Letters 2024 29:75
  19. By analyzing a mouse Interspecific Recombinant Congenic Strain (IRCS), we previously identified a quantitative trait locus (QTL), called Mafq1 on mouse chromosome 1, that is associated with male hypofertility and...

    Authors: Sophie Dupuis, Marie-Sophie Girault, Morgane Le Beulze, Côme Ialy-Radio, Luis Bermúdez-Guzmán, Ahmed Ziyyat and Sandrine Barbaux
    Citation: Cellular & Molecular Biology Letters 2024 29:74
  20. Reproductive cancers are malignancies that develop in the reproductive organs. One of the leading cancers affecting the male reproductive system on a global scale is prostate cancer (PCa). The negative consequ...

    Authors: Amin Ullah, Wang Jiao and Bairong Shen
    Citation: Cellular & Molecular Biology Letters 2024 29:73
  21. Aberrant mitochondrial fission, a critical pathological event underlying myocardial ischemia/reperfusion (MI/R) injury, has emerged as a potential therapeutic target. The long non-coding RNA (lncRNA) Oip5-as1 ...

    Authors: Xiaowei Niu, Jingjing Zhang, Shuwen Hu, Wenhui Dang, Kaiwen Wang and Ming Bai
    Citation: Cellular & Molecular Biology Letters 2024 29:72
  22. Genetic abnormalities in the FGFR signalling occur in 40% of breast cancer (BCa) patients resistant to anti-ER therapy, which emphasizes the potential of FGFR-targeting strategies. Recent findings indicate tha...

    Authors: Monika Gorska-Arcisz, Marta Popeda, Marcin Braun, Dominika Piasecka, Joanna I. Nowak, Kamila Kitowska, Grzegorz Stasilojc, Marcin Okroj, Hanna M. Romanska and Rafal Sadej
    Citation: Cellular & Molecular Biology Letters 2024 29:71
  23. Mycobacterium tuberculosis heat-resistant antigen (Mtb-HAg) is a peptide antigen released from the mycobacterial cytoplasm into the supernatant of Mycobacterium tuberculosis (Mtb) attenuated H37Ra strain after au...

    Authors: Jing Wei, Fangzheng Guo, Yamin Song, Tong Feng, Ying Wang, Kun Xu, Jianhan Song, Eldana Kaysar, Reyima Abdukayyum, Feiyang Lin, Kangsheng Li, Baiqing Li, Zhongqing Qian, Xiaojing Wang, Hongtao Wang and Tao Xu
    Citation: Cellular & Molecular Biology Letters 2024 29:70
  24. Pulmonary hypertension (PH) is a progressive disease characterized by pulmonary vascular remodeling. Increasing evidence indicates that endothelial-to-mesenchymal transition (EndMT) in pulmonary artery endothe...

    Authors: Kang Kang, Jingjing Xiang, Xingshi Zhang, Yuting Xie, Mengting Zhou, Le Zeng, Junhao Zhuang, Jiahao Kuang, Yuanyuan Lin, Bozhe Hu, Qianmin Xiong, Qing Yin, Qiang Su, Xiaoyun Liao, Jun Wang, Yanqin Niu…
    Citation: Cellular & Molecular Biology Letters 2024 29:69
  25. Members of the nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing (NLRP) family regulate various physiological and pathological processes. However, none have been shown ...

    Authors: Li-Ya Shi, Yang Wang, Yan-Jie Yang, Qian Li, Zhi-Xia Yang, Li-Hua Sun, Fu-Qiang Luo, Yu-hao He, Shu-Ping Zhang, Ning Su, Jia-Qi Liu, Ye He, Yi-Chun Guan, Zhao-Lian Wei, Yun-Xia Cao and Dong Zhang
    Citation: Cellular & Molecular Biology Letters 2024 29:68
  26. It is generally accepted that endothelial cells (ECs), primarily rely on glycolysis for ATP production, despite having functional mitochondria. However, it is also known that ECs are heterogeneous, and their p...

    Authors: Patrycja Kaczara, Izabela Czyzynska-Cichon, Edyta Kus, Anna Kurpinska, Mariola Olkowicz, Kamila Wojnar-Lason, Marta Z. Pacia, Olena Lytvynenko, Myriam Baes and Stefan Chlopicki
    Citation: Cellular & Molecular Biology Letters 2024 29:67
  27. The engineered clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated protein (Cas) system is currently widely applied in genetic editing and transcriptional regulation. The catal...

    Authors: Ziqi He, Caitao Dong, Tianbao Song, Jiawei Zhou, Tao Xu, Ruyuan He and Sheng Li
    Citation: Cellular & Molecular Biology Letters 2024 29:65
  28. Osteoarthritis (OA), known as one of the most common types of aseptic inflammation of the musculoskeletal system, is characterized by chronic pain and whole-joint lesions. With cellular and molecular changes i...

    Authors: Shicheng Jia, Rongji Liang, Jiayou Chen, Shuai Liao, Jianjing Lin and Wei Li
    Citation: Cellular & Molecular Biology Letters 2024 29:64
  29. Endometrial cancer (EC) is one of the most common gynecological cancers. Herein, we aimed to define the role of specific myosin family members in EC because this protein family is involved in the progression o...

    Authors: Yibin Lin, Xiao Chen, Linping Lin, Benhua Xu, Xiaofeng Zhu and Xian Lin
    Citation: Cellular & Molecular Biology Letters 2024 29:63
  30. Enhancing angiogenesis may be an effective strategy to promote functional recovery after ischemic stroke. Inflammation regulates angiogenesis. Microglia are crucial cells that initiate inflammatory responses a...

    Authors: Ting Chen, Xin Huang, Yi-Xuan Zhao, Zhi-wen Zhou and Wen-sheng Zhou
    Citation: Cellular & Molecular Biology Letters 2024 29:62
  31. Macrophage proinflammatory activation contributes to the pathology of severe acute pancreatitis (SAP) and, simultaneously, macrophage functional changes, and increased pyroptosis/necrosis can further exacerbat...

    Authors: Yiqiu Peng, Yuxi Yang, Yingying Li, Tingjuan Shi, Ning Xu, Ruixia Liu, Yingyi Luan, Yongming Yao and Chenghong Yin
    Citation: Cellular & Molecular Biology Letters 2024 29:61
  32. Cancer therapeutic resistance remains a significant challenge in the pursuit of effective treatment strategies. Circular RNAs (circRNAs), a class of non-coding RNAs, have recently emerged as key regulators of ...

    Authors: Ting Wang, Mengjie He, Xudong Zhang, Zhixun Guo, Pinghan Wang and Fangyi Long
    Citation: Cellular & Molecular Biology Letters 2024 29:60
  33. Skeletal muscle is the largest metabolic organ of the human body. Maintaining the best quality control and functional integrity of mitochondria is essential for the health of skeletal muscle. However, mitochon...

    Authors: Yuhang Lei, Mailin Gan, Yanhao Qiu, Qiuyang Chen, Xingyu Wang, Tianci Liao, Mengying Zhao, Lei Chen, Shunhua Zhang, Ye Zhao, Lili Niu, Yan Wang, Li Zhu and Linyuan Shen
    Citation: Cellular & Molecular Biology Letters 2024 29:59
  34. Non-small cell lung cancer (NSCLC), characterized by low survival rates and a high recurrence rate, is a major cause of cancer-related mortality. Aberrant activation of the PI3K/AKT/mTOR signaling pathway is a...

    Authors: Xiao-Qian Li, Xiao-Ju Cheng, Jie Wu, Kai-Feng Wu and Tie Liu
    Citation: Cellular & Molecular Biology Letters 2024 29:58
  35. In tomato (Solanum lycopersicum), the ripening of fruit is regulated by the selective expression of ripening-related genes, and this procedure is controlled by transcription factors (TFs). In the various plant-sp...

    Authors: Changxia Li, Xuemei Hou, Zongxi Zhao, Huwei Liu, Panpan Huang, Meimei Shi, Xuetong Wu, Rong Gao, Zhiya Liu, Lijuan Wei, Yihua Li and Weibiao Liao
    Citation: Cellular & Molecular Biology Letters 2024 29:57
  36. During growth phase, antlers exhibit a very rapid rate of chondrogenesis. The antler is formed from its growth center reserve mesenchyme (RM) cells, which have been found to be the derivatives of paired relate...

    Authors: Pengfei Hu, Guokun Zhang, Hengxing Ba, Jing Ren, Jiping Li, Zhen Wang and Chunyi Li
    Citation: Cellular & Molecular Biology Letters 2024 29:56
  37. Viral myocarditis (VMC) is a disease resulting from viral infection, which manifests as inflammation of myocardial cells. Until now, the treatment of VMC is still a great challenge for clinicians. Increasing s...

    Authors: Ya Wang, Zhengyang Zhang, Hui Li, Min Wang, Yuting Qiu and Lili Lu
    Citation: Cellular & Molecular Biology Letters 2024 29:55
  38. The trafficking of cargoes from endosomes to the trans-Golgi network requires numerous sequential and coordinated steps. Cargoes are sorted into endosomal-derived carriers that are transported, tethered, and fuse...

    Authors: Jérôme Gilleron, Abderrahman Chafik, Sandra Lacas-Gervais, Jean-François Tanti and Mireille Cormont
    Citation: Cellular & Molecular Biology Letters 2024 29:54
  39. Reactive oxygen species (ROS) serve as typical metabolic byproducts of aerobic life and play a pivotal role in redox reactions and signal transduction pathways. Contingent upon their concentration, ROS product...

    Authors: Qiangan Jing, Chaoting Zhou, Junyu Zhang, Ping Zhang, Yunyi Wu, Junyu Zhou, Xiangmin Tong, Yanchun Li, Jing Du and Ying Wang
    Citation: Cellular & Molecular Biology Letters 2024 29:53
  40. T cell immunity is central to contemporary cancer and autoimmune therapies, encompassing immune checkpoint blockade and adoptive T cell therapies. Their diverse characteristics can be reprogrammed by different...

    Authors: Xiaoying Chen, Shuhan Zhong, Yonghao Zhan and Xuepei Zhang
    Citation: Cellular & Molecular Biology Letters 2024 29:52
  41. Melanoma is the most lethal skin cancer characterized by its high metastatic potential. In the past decade, targeted and immunotherapy have brought revolutionary survival benefits to patients with advanced and...

    Authors: Weisong Li, Chao Zheng, Xi Xu, Yujie Xia, Kai Zhang, Ao Huang, Xinyu Zhang, Yong Zheng, Guofang Chen and Shuyong Zhang
    Citation: Cellular & Molecular Biology Letters 2024 29:50
  42. Clustered regularly interspaced short palindromic repeats and associated Cas protein (CRISPR–Cas), a powerful genome editing tool, has revolutionized gene function investigation and exhibits huge potential for...

    Authors: Ying Wang, Yujing Zhai, Mingzhe Zhang, Chunlin Song, Yuqing Zhang and Gang Zhang
    Citation: Cellular & Molecular Biology Letters 2024 29:48
  43. Glucose-6-phosphate dehydrogenase (G6PD) plays an important role in vascular smooth muscle cell (VSMC) phenotypic switching, which is an early pathogenic event in various vascular remodeling diseases (VRDs). H...

    Authors: Ting Zhang, Rui-Jie Cao, Jiang-Ling Niu, Zhi-Huan Chen, Shi-Qing Mu, Tong Cao, Jie-Xin Pang and Li-Hua Dong
    Citation: Cellular & Molecular Biology Letters 2024 29:47

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