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Cellular & Molecular Biology Letters

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Archival content

Cellular & Molecular Biology Letters was founded in 1996 and transferred to BioMed Central in 2016. Previously, its publishers were Walter De Gruyter in 2015 (content available from De Gruyter's archive), and Springer from 2006–2014 (content available from BMC web page). Articles published between 1996 and 2005 can be found at, CMBL home page, the Volume List tab. To request free electronic versions of these articles, please contact

Thematic Series

Invited Papers

The papers in this collection were specially invited by the editors and represent work by leading researchers in their fields, as well the authors of the most cited papers from the previous issues of our journal (CMBL).

All Articles

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  1. Content type: Review

    The development and integration of bio- and chemocatalytic processes to convert renewable or biomass feedstocks into polymers is a vibrant field of research with enormous potential for environmental protection...

    Authors: Aleksandra Marszałek-Harych, Dawid Jędrzkiewicz and Jolanta Ejfler

    Citation: Cellular & Molecular Biology Letters 2017 22:28

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  2. Content type: Short report

    Prolyl-hydroxyproline (Pro-Hyp) is one of the major constituents of collagen-derived dipeptides. We previously reported that Pro-Hyp promotes the differentiation of osteoblasts by increasing Runx2, osterix and...

    Authors: Yoshifumi Kimira, Haruka Odaira, Kaho Nomura, Yuri Taniuchi, Naoki Inoue, Sachie Nakatani, Jun Shimizu, Masahiro Wada and Hiroshi Mano

    Citation: Cellular & Molecular Biology Letters 2017 22:27

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  3. Content type: Short report

    Many studies have investigated the characteristics and biological activities of type III interferon (IFN), finding that it has similar features to type I IFN but also unique actions because it is recognized by...

    Authors: Wu-mei Yuan, Wan-ju Zhang, Fen-lian Ma, Jin-song Li, Qian Zhang and Li-shu Zheng

    Citation: Cellular & Molecular Biology Letters 2017 22:26

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  4. Content type: Short report

    The rupture of a brain aneurysm causes bleeding in the subarachnoid space. This is known as aneurysmal subarachnoid hemorrhage (aSAH). We evaluated the association of apolipoprotein E (APOE) polymorphism and the ...

    Authors: Arati Suvatha, Sibin Madathan Kandi, Dhananjaya Ishwara Bhat, Narasinga Rao, Vikas Vazhayil and Chetan Ghati Kasturirangan

    Citation: Cellular & Molecular Biology Letters 2017 22:25

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  5. Content type: Research

    Thoracic aortic dissection (TAD) is one of the most severe aortic diseases. The study aimed to explore the potential role of heat shock protein 27 (HSP27) in the pathogenesis of TAD using an in vitro model of ...

    Authors: Sili Zou, Mingfang Liao, Junlin Yang, Tong Huang, Mark Green, Jianjin Wu and Lefeng Qu

    Citation: Cellular & Molecular Biology Letters 2017 22:24

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  6. Content type: Research article

    Hypoxic conditions induce the expression of hypoxia-inducible factors (HIFs) that allow cells to adapt to the changing conditions and alter the expression of a number of genes including the cystic fibrosis tra...

    Authors: Sylwia Bartoszewska, Wojciech Kamysz, Bogdan Jakiela, Marek Sanak, Jarosław Króliczewski, Zsuzsa Bebok, Rafal Bartoszewski and James F. Collawn

    Citation: Cellular & Molecular Biology Letters 2017 22:23

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  7. Content type: Research

    TGF-β1 plays an important role in the epithelial–mesenchymal transition (EMT) of epithelial cancers, including non-small cell lung cancer (NSCLC). While the full underlying mechanism remains unclear, miR-9 is ...

    Authors: Hui Wang, Qian Wu, Ying Zhang, Hua-Nan Zhang, Yong-Bin Wang and Wei Wang

    Citation: Cellular & Molecular Biology Letters 2017 22:22

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  8. Content type: Short report

    Our previous study found that single-pass membrane protein with coiled-coil domains 1 (C3orf43; XM_006248472.3) was significantly upregulated in the proliferative phase during liver regeneration. This indicate...

    Authors: Chunyan Zhang, Cuifang Chang, Deming Li, Fuchun Zhang and Cunshuan Xu

    Citation: Cellular & Molecular Biology Letters 2017 22:21

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  9. Content type: Mini review

    Clinicians use clinical and pathological parameters, such as tumour size, grade and nodal status, to make decisions on adjuvant treatments for breast cancer. However, therapeutic decisions based on these featu...

    Authors: Umar Wazir, Kinan Mokbel, Amtul Carmichael and Kefah Mokbel

    Citation: Cellular & Molecular Biology Letters 2017 22:20

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  10. Content type: Research

    One of the microorganisms from dental plaque associated with severe inflammatory responses in infectious endocarditis is Porphyromonas gingivalis. It is a Gram-negative bacteria harvested from chronic periodontit...

    Authors: Gloria Gutiérrez-Venegas, Alfredo Torras-Ceballos, Juan Arturo Gómez-Mora and Berenice Fernández-Rojas

    Citation: Cellular & Molecular Biology Letters 2017 22:19

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  11. Content type: Review

    In mammals, genomic DNA that is roughly 2 m long is folded to fit the size of the cell nucleus that has a diameter of about 10 μm. The folding of genomic DNA is mediated via assembly of DNA-protein complex, ch...

    Authors: Sergey V. Razin and Sergey V. Ulianov

    Citation: Cellular & Molecular Biology Letters 2017 22:18

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  12. Content type: Short report

    Retinoblastoma (RB), a childhood cancer, is caused by biallelic mutation of the RB1 gene, but its development is not clearly understood. Furthermore, the presence of a cancer stem cell subpopulation in RB might i...

    Authors: Suganya Sivagurunathan, Jayamuruga Pandian Arunachalam and Subbulakshmi Chidambaram

    Citation: Cellular & Molecular Biology Letters 2017 22:17

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  13. Content type: Short report

    Nur-77, a member of the NR4A sub-family of nuclear orphan receptors, is downregulated in the placentae of pre-eclamptic women. Here, we investigate the relevance of Nor-1, Nurr-1 and Nur-77 in trophoblastic ce...

    Authors: Sudha Saryu Malhotra and Satish Kumar Gupta

    Citation: Cellular & Molecular Biology Letters 2017 22:15

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  14. Content type: Research

    Exploring the molecular mechanisms underlying directed differentiation is helpful in the development of clinical applications of mesenchymal stem cells (MSCs). Our previous study on dental tissue-derived MSCs ...

    Authors: Luyuan Jin, Yu Cao, Guoxia Yu, Jinsong Wang, Xiao Lin, Lihua Ge, Juan Du, Liping Wang, Shu Diao, Xiaomeng Lian, Songlin Wang, Rui Dong and Zhaochen Shan

    Citation: Cellular & Molecular Biology Letters 2017 22:14

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  15. Content type: Research

    FFA1 is abundantly expressed in the liver, skeletal muscle, monocytes and nervous system, but is particularly abundant in pancreatic β cells. It is widely believed that FFA1 exerts its regulatory roles in a va...

    Authors: Jing Qian, Yuyang Gu, Chun Wu, Feng Yu, Yuqi Chen, Jingmei Zhu, Xingyi Yao, Chen Bei and Qingqing Zhu

    Citation: Cellular & Molecular Biology Letters 2017 22:13

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  16. Content type: Research

    MicroRNAs (miRNAs) play important roles in the growth and metastasis of colon cancer. It is known that one set of miRNAs are dysregulated in colon cancer cells, but the mechanism of their role in cancer develo...

    Authors: Mingxi Zeng, Linlin Zhu, Liangping Li and Changming Kang

    Citation: Cellular & Molecular Biology Letters 2017 22:12

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  17. Content type: Review

    Human milk is a complex fluid that has developed to satisfy the nutritional requirements of infants. In addition to proteins, lipids, carbohydrates and other biologically active components, breast milk contain...

    Authors: Malgorzata Witkowska-Zimny and Ewa Kaminska-El-Hassan

    Citation: Cellular & Molecular Biology Letters 2017 22:11

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  18. Content type: Short report

    H19 is a well-characterized Long noncoding RNA (lncRNA) that has been proven to promote myoblast differentiation in humans and mice. However, its mechanism of action is still not fully interpreted.

    Authors: Xiaochun Xu, Shengyue Ji, Weili Li, Bao Yi, Hengxin Li, Hongfu Zhang and Wenping Ma

    Citation: Cellular & Molecular Biology Letters 2017 22:10

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  19. Content type: Short report

    The gene that encodes tumor protein p53, Tp53, is mutated or silenced in most human cancers and is recognized as one of the most important cancer drivers. Homozygotic Tp53 knockout mice, which develop lethal canc...

    Authors: Damian Strzemecki, Magdalena Guzowska and Paweł Grieb

    Citation: Cellular & Molecular Biology Letters 2017 22:9

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  20. Content type: Review

    Squamous cell carcinoma (SCC) is the most common cancer worldwide. The treatment of locally advanced disease generally requires various combinations of radiotherapy, surgery, and systemic therapy. Despite aggr...

    Authors: Zakir Khan, Abdul Arif Khan, Hariom Yadav, Godavarthi B. K. S. Prasad and Prakash Singh Bisen

    Citation: Cellular & Molecular Biology Letters 2017 22:8

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  21. Content type: Short Report

    Pseudoxanthoma elasticum (PXE) is characterized by progressive ectopic mineralization of elastic fibers in dermal, ocular and vascular tissues. No effective treatment exists. It is caused by inactivating mutat...

    Authors: Rocchina Miglionico, Angela Ostuni, Maria Francesca Armentano, Luigi Milella, Elvira Crescenzi, Monica Carmosino and Faustino Bisaccia

    Citation: Cellular & Molecular Biology Letters 2017 22:7

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  22. Content type: Short report

    Although the 3T3-L1 preadipocyte cell line represents an informative model for in vitro adipogenesis research, primary cultured cells are often needed to understand particular human or animal metabolic phenotypes...

    Authors: Yong Pu and Almudena Veiga-Lopez

    Citation: Cellular & Molecular Biology Letters 2017 22:6

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  23. Content type: Research

    Human Tenon’s fibroblasts (HTFs) play a crucial role in wound healing. They cause postoperative scarring of the filtering bleb and are thus responsible for trabeculectomy failure. This study aimed to find an e...

    Authors: Agata Przekora, Tomasz Zarnowski and Grazyna Ginalska

    Citation: Cellular & Molecular Biology Letters 2017 22:5

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  24. Content type: Mini review

    Neuron-glial antigen 2 (NG2), also known as chondroitin sulphate proteoglycan 4 (CSPG4), is a surface type I transmembrane core proteoglycan that is crucially involved in cell survival, migration and angiogene...

    Authors: Emmanuel Ampofo, Beate M. Schmitt, Michael D. Menger and Matthias W. Laschke

    Citation: Cellular & Molecular Biology Letters 2017 22:4

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