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  1. Content type: Research

    Although significant advances have been made in understanding the mechanisms of macrophage response to Staphylococcus aureus infection, the molecular details are still elusive. Identification of the essential gen...

    Authors: Aixia Sun, Hongwei Zhang, Feng Pang, Guifen Niu, Jianzhong Chen, Fei Chen and Jian Zhang

    Citation: Cellular & Molecular Biology Letters 2018 23:25

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  2. Content type: Short report

    Patients with anti-β2GPI antibodies display significantly higher platelet activation/aggregation and vascular endothelial cell damage. The mechanism underlying the correlation between platelet activation, vasc...

    Authors: Yanfen Zhang, Wenjing Zhang, Caijun Zha and Yanhong Liu

    Citation: Cellular & Molecular Biology Letters 2018 23:24

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  3. Content type: Short report

    The levels of decoy receptor 3 (DcR3), soluble urokinase type plasminogen activator receptor (suPAR) and procalcitonin (PCT) are significantly increased in sepsis. We investigated the diagnostic value of DcR3 ...

    Authors: Jing-jing Zhao, Xiao-Li Lou, Hong-wei Chen, Feng-ting Zhu and Yan-Qiang Hou

    Citation: Cellular & Molecular Biology Letters 2018 23:22

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  4. Content type: Research

    MicroRNAs (miRNAs) have physiological and pathophysiological functions that are involved in the regulation of cardiac fibrosis. This study aimed to investigate the effects of miR-495 on high glucose-induced ca...

    Authors: Xiaowei Wang, Haiying Jin, Shifeng Jiang and Yanlan Xu

    Citation: Cellular & Molecular Biology Letters 2018 23:23

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  5. Content type: Review

    Tumourigenic tissue uses modified metabolic signalling pathways in order to support hyperproliferation and survival. Cancer-associated aerobic glycolysis resulting in lactic acid production was described nearl...

    Authors: Mokgadi Violet Gwangwa, Anna Margaretha Joubert and Michelle Helen Visagie

    Citation: Cellular & Molecular Biology Letters 2018 23:20

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  6. Content type: Short report

    Osthole is a natural product that has multiple bioactive functions and has been reported to exert potent immunosuppressive effects. However, the therapeutic effect of osthole on arthritis has not been explored...

    Authors: Renguo Xu, Zhen Liu, Jiande Hou, Tao Huang and Ming Yang

    Citation: Cellular & Molecular Biology Letters 2018 23:19

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  7. Content type: Short report

    Lycium barbarum polysaccharide (LBP) is considered an antioxidant agent. NF-E2-related factor-2 (Nrf2) is an important regulator for protection against UV damage. In this study, we verified the performance of LBP...

    Authors: Bihua Liang, Liqian Peng, Runxiang Li, Huaping Li, Ziyin Mo, Xinyue Dai, Na Jiang, Qing Liu, Erting Zhang, Huiyan Deng, Zhenjie Li and Huilan Zhu

    Citation: Cellular & Molecular Biology Letters 2018 23:18

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  8. Content type: Research

    Epstein–Barr virus (EBV) infection is causatively associated with a variety of human cancers, including gastric cancer (GC), which has one of the highest mortality rates of all human cancers. Long non-coding R...

    Authors: Jing Liu, Chunxia Yang, Yufang Gu, Chong Li, Huamei Zhang, Wenfang Zhang, Xueqing Wang, Nan Wu and Chunyan Zheng

    Citation: Cellular & Molecular Biology Letters 2018 23:17

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  9. Content type: Research

    The leaves of Annona purpurea have yielded several alkaloids with anti-aggregation activities against rabbit platelets. This is promising in the search for agents that might act against platelets and reduce the i...

    Authors: Gabriela Sánchez, Omar Estrada, Giovana Acha, Alfonso Cardozo, Franshelle Peña, Marie Christine Ruiz, Fabián Michelangeli and Claudia Alvarado-Castillo

    Citation: Cellular & Molecular Biology Letters 2018 23:15

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  10. Content type: Short report

    The miRNA cluster miR-17-92 is known to act as an oncogene in various cancers. Members of this cluster were also found to be involved in some other pathological process, such as steatosis, which is a pivotal e...

    Authors: Ruijie Gong, Xiaofei Lv and Fengqiong Liu

    Citation: Cellular & Molecular Biology Letters 2018 23:16

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  11. Content type: Research

    The regulation of microglial function via mitochondrial homeostasis is important in the development of neuroinflammation. The underlying mechanism for this regulatory function remains unclear. In this study, w...

    Authors: Qingyun Lei, Jian Tan, Shangqing Yi, Na Wu, Yilin Wang and Heng Wu

    Citation: Cellular & Molecular Biology Letters 2018 23:14

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  12. Content type: Research

    Arsenic trioxide (As2O3) has a dramatic therapeutic effect on acute promyelocytic leukemia (APL) patients. It can also cause apoptosis in various tumor cells. This study investigated whether As2O3 has an antitumo...

    Authors: Yuanyuan Sun, Chen Wang, Ligang Wang, Zhibo Dai and Kongbin Yang

    Citation: Cellular & Molecular Biology Letters 2018 23:13

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  13. Content type: Review

    Signal Transducer and Activator of Transcription 3 (STAT3) is a transcription factor with many important functions in the biology of normal and transformed cells. Its regulation is highly complex as it is invo...

    Authors: Michaela Galoczova, Philip Coates and Borivoj Vojtesek

    Citation: Cellular & Molecular Biology Letters 2018 23:12

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  14. Content type: Research

    The majority of novel chemotherapeutics target the cell cycle, aiming to effect arrest and cause apoptosis. One such agent, 2-methoxyestradiol (2ME), has been shown to possess anticancer properties against num...

    Authors: Laura Susan Boyd, Devrim Gozuacik and Anna Margaretha Joubert

    Citation: Cellular & Molecular Biology Letters 2018 23:10

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  15. Content type: Short report

    Articular cartilage has a poor capacity for self-repair, and thus still presents a major challenge in orthopedics. Mesenchymal stem cells (MSCs) are multipotent stem cells with the potential to differentiate i...

    Authors: Ghmkin Hassan, Mohammad Bahjat, Issam Kasem, Chadi Soukkarieh and Majd Aljamali

    Citation: Cellular & Molecular Biology Letters 2018 23:11

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  16. Content type: Short report

    Previous studies indicated that cadmium (Cd) increases PI3-kinase/Akt phosphorylation, resulting in an alteration in GSK-3β activity. However, the mechanism of Cd-induced endoplasmic reticulum (ER) stress in n...

    Authors: Seungwoo Kim, Hyosoon Cheon, Sam-Moon Kim and Young-Youl Kim

    Citation: Cellular & Molecular Biology Letters 2018 23:9

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  17. Content type: Research

    Platelet-derived growth factor-C (PDGF-C) has been shown to be involved in several biological processes, such as embryonic development, wound healing and angiogenesis, as well as in diseases including tumor fo...

    Authors: Tomoaki Kinjo, Chuanhai Sun, Tomomi Ikeda, Takako Ikegami, Yuhki Tada, Tadayuki Akagi, Takashi Yokota and Hiroshi Koide

    Citation: Cellular & Molecular Biology Letters 2018 23:8

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  18. Content type: Research

    Osteoarthritis is characterized by the continuous degradation of the articular cartilage. The microRNA miR-448 has been found to be broadly involved in cellular processes, including proliferation, apoptosis, i...

    Authors: Hao Yang, Di Wu, Hua Li, Nan Chen and Yongjun Shang

    Citation: Cellular & Molecular Biology Letters 2018 23:7

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  19. Content type: Research

    Laryngeal cancer tends to have a very poor prognosis due to the unsatisfactory efficacy of chemotherapy for this cancer. Multidrug resistance (MDR) is the main cause of chemotherapy failure. The proto-oncogene...

    Authors: Guodong Li, Xiaoling Hu, Lu Sun, Xin Li, Jianfeng Li, Tongli Li and Xiaohui Zhang

    Citation: Cellular & Molecular Biology Letters 2018 23:6

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  20. Content type: Research

    Perineuronal nets (PNNs), which are localized around neurons during development, are specialized forms of neural extracellular matrix with neuroprotective and plasticity-regulating roles. Hyaluronan and proteo...

    Authors: Nazli F. Eskici, Sevim Erdem-Ozdamar and Didem Dayangac-Erden

    Citation: Cellular & Molecular Biology Letters 2018 23:5

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  21. Content type: Research

    Calcitonin gene-related peptide (CGRP) can protect against hyperoxia-induced lung injury, making the upregulation of CGRP a potential therapeutic approach for this type of injury. However, the effects of CGRP ...

    Authors: Shaohua Wang, Hongxing Dang, Feng Xu, Jian Deng and Xuemei Zheng

    Citation: Cellular & Molecular Biology Letters 2018 23:4

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  22. Content type: Short report

    Endoxifen, an active metabolite of tamoxifen, has been shown to be an effective anti-estrogenic agent in estrogen receptor-positive breast cancer patients. In melanoma, estrogen receptor expression is shown to...

    Authors: Paul Chen, Saifuddin Sheikh, Ateeq Ahmad, Shoukath M. Ali, Moghis U. Ahmad and Imran Ahmad

    Citation: Cellular & Molecular Biology Letters 2018 23:3

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  23. Content type: Research

    Anti-angiogenesis therapy that targets VEGF is one of the important treatment strategies in advanced ovarian cancer. However, depending on the pharmaceutical agent, treatment can have undesirable side effects....

    Authors: Ying Chen, Lei Zhang, Wen-xin Liu and Ke Wang

    Citation: Cellular & Molecular Biology Letters 2018 23:2

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  24. Content type: Short report

    Our previous study showed that during in vitro experiments changes in calcium concentration were associated with apoptosis. We presumed that the calcium ion might play a role as intermediate messenger for apop...

    Authors: Yanan Li, Yu Yan, Fang Liu, Ming Wang, Fumin Feng and Yonghong Xiao

    Citation: Cellular & Molecular Biology Letters 2018 23:1

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