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  1. Content type: Research Letter

    Synuclein-γ has been demonstrated to be highly expressed in various human cancers including cervical cancer, and has been shown to play a critical role in tumor aggressiveness. We aimed to investigate the role of...

    Authors: Chunnian Zhang, Liqin Gu, Xiafang Li and Jianzhong Wang

    Citation: Cellular & Molecular Biology Letters 2019 24:49

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  2. Content type: Research Letter

    In recent years, microRNA-211 (miR211) has been considered as a tumor suppressor in multiple malignancies. However, the function of miR211 in human osteosarcoma has not been explored intensively so far. In thi...

    Authors: Yihua Pei, Qin Yao, Yingchao Li, Xin Zhang and Bozhen Xie

    Citation: Cellular & Molecular Biology Letters 2019 24:48

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  3. Content type: Research

    Chemotherapy based on paclitaxel (PTX) is the standard treatment for a range of cancers, including triple-negative breast cancer (TNBC), but the increasing development of resistance has reduced/has negatively ...

    Authors: Mei Liu, Can Gong, Renyuan Xu, Yu Chen and Xiaodong Wang

    Citation: Cellular & Molecular Biology Letters 2019 24:47

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  4. Content type: Research

    The study aimed to investigate the effect of oxidative stress on Prestin expression, and explore the transcription factors (TFs) that are involved in regulating the expression of Prestin in House Ear Institute-Or...

    Authors: Xuan Luo, Yun Xia, Xu-Dong Li and Jun-Yi Wang

    Citation: Cellular & Molecular Biology Letters 2019 24:45

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  5. Content type: Research Letter

    Deer antler is the only mammalian organ that can be completely regenerated every year. Its periodic regeneration is regulated by multiple factors, including transforming growth factor β (TGF-β). This widely di...

    Authors: Mingxiao Liu, Xiangyu Han, Hongyun Liu, Danyang Chen, Yue Li and Wei Hu

    Citation: Cellular & Molecular Biology Letters 2019 24:44

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  6. Content type: Research

    Impairment of the blood–brain barrier (BBB) could result in secondary cerebral edema and life-threatening pancreatic encephalopathy in patients with severe acute pancreatitis (SAP). Mesenchymal stem cells (MSC...

    Authors: Ronggui Lin, Ming Li, Meiqin Luo, Tianhong Teng, Yu Pan and Heguang Huang

    Citation: Cellular & Molecular Biology Letters 2019 24:43

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  7. Content type: Research

    Human bronchial epithelium (HBE)-Dp71 anti-sense(AS)cells with stably transfected Dp71 siRNA plasmids were prepared for further exploration of Dp71 biological traits in cells other than PC12. HBE-Dp71AS cells ...

    Authors: Sichuang Tan, Shuai Zhao, Xuefei Xiao, Lan Xiao, Jinliang Xie and Sipin Tan

    Citation: Cellular & Molecular Biology Letters 2019 24:42

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  8. Content type: Review Letter

    Paclitaxel is a well-known anticancer agent with a unique mechanism of action. It is considered to be one of the most successful natural anticancer drugs available. This study summarizes the recent advances in...

    Authors: Linyan Zhu and Liqun Chen

    Citation: Cellular & Molecular Biology Letters 2019 24:40

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  9. Content type: Research Letter

    The aim of this study was to investigate the effect of human umbilical vein endothelial cells on epithelial-to-mesenchymal transition of the cervical cancer cell line SiHa by studying the Notch1/lysyl oxidase ...

    Authors: Jinghua Ou, Defeng Guan and Yongxiu Yang

    Citation: Cellular & Molecular Biology Letters 2019 24:39

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  10. Content type: Research

    Exploration of the genes with abnormal expression during the development of breast cancer is essential to provide a deeper understanding of the mechanisms involved. Transcriptome sequencing and bioinformatics ...

    Authors: Yulong Bao, Li Wang, Lin Shi, Fen Yun, Xia Liu, Yongxia Chen, Chen Chen, Yanni Ren and Yongfeng Jia

    Citation: Cellular & Molecular Biology Letters 2019 24:38

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  11. Content type: Research

    Accumulating evidence has shown that altered microRNA (miR) modulation is implicated in the pathologies of ischemic stroke. However, it is unclear whether and how hsa-miR-19a-3p mediates cerebral ischemic inju...

    Authors: Xiao-Li Ge, Jin-Li Wang, Xin Liu, Jia Zhang, Chang Liu and Li Guo

    Citation: Cellular & Molecular Biology Letters 2019 24:37

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  12. Content type: Review

    Common environmental pollutants and drugs encountered in everyday life can cause toxic damage to the body through oxidative stress, inflammatory stimulation, induction of apoptosis, and inhibition of energy me...

    Authors: Zhihua Ren, Hongyi He, Zhicai Zuo, Zhiwen Xu, Zhanyong Wei and Junliang Deng

    Citation: Cellular & Molecular Biology Letters 2019 24:36

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  13. Content type: Short report

    Pulmonary edema is one of the pathological characteristics of acute respiratory distress syndrome (ARDS). The epithelial sodium channel (ENaC) is thought to be the rate-limiting factor for alveolar fluid clear...

    Authors: Jing He, Di Qi, Xu-mao Tang, Wang Deng, Xin-yu Deng, Yan Zhao and Dao-xin Wang

    Citation: Cellular & Molecular Biology Letters 2019 24:35

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  14. Content type: Short report

    Induction of lysosomal function and autophagy is regarded as an adaptive mechanism in response to cellular stress. The transcription factor EB (TFEB) has been identified as a master regulator of lysosomal func...

    Authors: Hsuan-Yeh Pan, Abdulla H. Alamri and Mallika Valapala

    Citation: Cellular & Molecular Biology Letters 2019 24:33

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  15. Content type: Research Letter

    Peritoneal fibrosis remains a serious complication of long-term peritoneal dialysis (PD) leading to peritoneal membrane ultrafiltration failure. Epithelial–mesenchymal transition (EMT) of peritoneal mesothelia...

    Authors: Jun-Li Zhao, Mei-Zi Guo, Jun-Jun Zhu, Ting Zhang and Dan-Yan Min

    Citation: Cellular & Molecular Biology Letters 2019 24:32

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  16. Content type: Short report

    Gemcitabine (2′,2′-difluoro-2′-deoxycytidine;dFdC) is a first-line chemotherapy drug for pancreatic cancer. Recently, a synergistic anti-tumor treatment of dFdC and hyperthermia has achieved good clinical resu...

    Authors: HB Jin, L Lu, L Xie, JF Yang, XF Zhang and SL Ma

    Citation: Cellular & Molecular Biology Letters 2019 24:30

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  17. Content type: Research Letter

    In its RING domain, tumor necrosis factor receptor-associated factor 6 (TRAF6) has ubiquitin E3 ligase activity that facilitates the formation of lysine 63-linked polyubiquitin chains. This activity is require...

    Authors: Hyun-Duk Jang, Hye Zin Hwang, Hyo-Soo Kim and Soo Young Lee

    Citation: Cellular & Molecular Biology Letters 2019 24:29

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  18. Content type: Short report

    Hypoxia-inducible factor-1α (HIF-1α) is a transcription factor with a pivotal role in physiological and pathological responses to hypoxia. While HIF-1α is known to be involved in hypoxia-induced upregulation o...

    Authors: Yuree Byun, Young-Chul Choi, Yunhui Jeong, Gangtae Lee, Sena Yoon, Yongsu Jeong, Jaeseung Yoon and Kwanghee Baek

    Citation: Cellular & Molecular Biology Letters 2019 24:28

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  19. Content type: Research

    This study aimed to investigate the effects of miR-613 on the proliferation, invasion and apoptosis of rheumatoid arthritis synovial fibroblasts (RASFs).

    Authors: Liang Liu, Yanhua Zuo, Yan Xu, Zongfang Zhang, Ying Li and Jie Pang

    Citation: Cellular & Molecular Biology Letters 2019 24:8

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  20. Content type: Research Letter

    Given the high mortality rate and unclear pathogenesis for liver cancer, investigation of its molecular mechanisms is essential. We focused on the long non-coding RNA (lncRNA) MIR4435-2HG, which was recently r...

    Authors: Qinglei Kong, Caiqian Liang, Yi Jin, Yuhang Pan, Dayue Tong, Qingcong Kong and Jing Zhou

    Citation: Cellular & Molecular Biology Letters 2019 24:26

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  21. Content type: Research

    Autologous cultivated oral mucosal epithelial transplantation (COMET) is an important treatment for limbal stem cell deficiency. However, peripheral corneal neovascularization after surgery hinders its applica...

    Authors: Chao-Ye Duan, Hua-Tao Xie, Xin-Yue Zhao, Wen-Han Xu and Ming-Chang Zhang

    Citation: Cellular & Molecular Biology Letters 2019 24:3

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  22. Content type: Research

    Pulmonary surfactant is the complex mixture of lipid and protein that covers the alveolar surface. Pulmonary surfactant deficiency is one of the main causes of neonatal respiratory distress. Recent studies sho...

    Authors: Shujun Li, Zhongyi Sun, Tao Chen, Jingjing Pan, Yanqing Shen, Xiaoqing Chen, Xiaoyu Zhou, Rui Cheng and Yang Yang

    Citation: Cellular & Molecular Biology Letters 2019 24:25

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  23. Content type: Short report

    Polysaccharides from various sources have been used in traditional medicine for centuries. The beneficial pharmacological effects of plant-derived polysaccharides include anti-tumor activity.

    Authors: Monique Meyenberg Cunha-de Padua, Guilhermina Rodrigues Noleto, Carmen Lucia de Oliveira Petkowicz, Silvia Maria Suter Correia Cadena, Frédéric Bost, Jacques Pouysségur and Nathalie M. Mazure

    Citation: Cellular & Molecular Biology Letters 2019 24:18

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  24. Content type: Short report

    The peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors that belong to the nuclear hormone receptor superfamily. Several studies have demonstrated a significant assoc...

    Authors: Leila Saremi, Shirin Lotfipanah, Masumeh Mohammadi, Hassan Hosseinzadeh, Mina Fathi-Kazerooni, Behrooz Johari and Zohreh Saltanatpour

    Citation: Cellular & Molecular Biology Letters 2019 24:12

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  25. Content type: Research

    Overcoming chemorestistance to 5-fluorouracil (5-FU) could offer a new treatment option for highly malignant colon cancer. In our study, differential microRNA expression profiling revealed that miR-214 is down...

    Authors: Yong Yang, Yan Bao, Guo-Kai Yang, Jia Wan, Ling-Juan Du and Zhen-Huan Ma

    Citation: Cellular & Molecular Biology Letters 2019 24:22

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  26. Content type: Research Letters

    Mechanical loading is an essential factor for bone formation. A previous study indicated that mechanical tensile strain of 2500 microstrain (με) at 0.5 Hz for 8 h promoted osteogenesis and corresponding mechan...

    Authors: Qiangcheng Zeng, Yang Wang, Jie Gao, Zhixiong Yan, Zhenghua Li, Xianqiong Zou, Yanan Li, Jiahui Wang and Yong Guo

    Citation: Cellular & Molecular Biology Letters 2019 24:11

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  27. Content type: Research

    Melatonin receptors MT1 and MT2 (genes officially named MTNR1A and MTNR1B, respectively) play crucial roles in melatonin-mediated regulation of circadian rhythms, the immune system, and control of reproduction...

    Authors: Yuan Gao, Xiaochun Wu, Shuqin Zhao, Yujun Zhang, Hailong Ma, Zhen Yang, Wanghao Yang, Chen Zhao, Li Wang and Quanwei Zhang

    Citation: Cellular & Molecular Biology Letters 2019 24:21

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  28. Content type: Short report

    This study was designed to investigate the potential role of microRNA-29c (miR-29c) in biliary atresia-related fibrosis. The expression of miR-29c was determined in 15 pairs of peripheral blood samples from in...

    Authors: Jian-yao Wang, Hao Cheng, Hong-yan Zhang, Yong-qin Ye, Qi Feng, Zi-min Chen, Yue-lan Zheng, Zhou-guang Wu, Bin Wang and Jun Yao

    Citation: Cellular & Molecular Biology Letters 2019 24:10

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  29. Content type: Research

    Cutaneous squamous cell carcinoma (CSCC) is a common type of skin malignancy. MicroRNA-221 (miRNA-221) is a critical non-coding RNA in tumor initiation and progression. However, the molecular mechanisms of miR...

    Authors: Zhen-Hua Gong, Feng Zhou, Chao Shi, Tie Xiang, Chang-Kai Zhou, Qian-Qian Wang, Ya-Su Jiang and Sheng-Feng Gao

    Citation: Cellular & Molecular Biology Letters 2019 24:9

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  30. Content type: Research Letters

    Cyclin-dependent kinase-like 1 (CDKL1) is a member of the cell division control protein 2-related serine–threonine protein kinase family. It is known to occur in various malignant tumors, but its role in neuro...

    Authors: Weiyi Li, Jing Cao, Jian Liu, Wenli Chu, Congqing Zhang, Shuiling Chen and Zefeng Kang

    Citation: Cellular & Molecular Biology Letters 2019 24:19

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  31. Content type: Research

    We investigated the protective effect of tetramethylpyrazine (TMP) on injury related to acute myocardial ischemia (AMI) induced by isoproterenol (ISO).

    Authors: Qing Yang, Dan Dan Huang, Da Guang Li, Bo Chen, Ling Min Zhang, Cui Ling Yuan and Hong Hong Huang

    Citation: Cellular & Molecular Biology Letters 2019 24:17

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  32. Content type: Research

    Indian hedgehog (IHH) and Sonic hedgehog (SHH) are important regulators of chondrogenesis. However, activation of IHH and SHH also promotes chondrocyte hypertrophy and ossification during chondrogenesis. The a...

    Authors: Liyang Chen, Gejun Liu, Wenjun Li and Xing Wu

    Citation: Cellular & Molecular Biology Letters 2019 24:16

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  33. Content type: Short report

    Tetrahydroxy stilbene glucoside (TSG) has been reported to exert a cytoprotective effect against various toxicants. However, the function and mechanism of TSG in palmitic acid (PA)-induced inflammation and apo...

    Authors: Yong ZOU and Min KONG

    Citation: Cellular & Molecular Biology Letters 2019 24:5

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  34. Content type: Short report

    The proliferation and adipogenic differentiation of adipose stromal cells (ASCs) are complex processes comprising major phenotypical alterations driven by up- and downregulation of hundreds of genes. Quantitat...

    Authors: Claudia Krautgasser, Markus Mandl, Florian M. Hatzmann, Petra Waldegger, Monika Mattesich and Werner Zwerschke

    Citation: Cellular & Molecular Biology Letters 2019 24:14

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  35. Content type: Research

    Hepatitis B virus (HBV) infection is acknowledged as the main cause of hepatocellular carcinoma (HCC). Moreover, previous studies have revealed that microRNAs (miRNAs) widely participate in regulation of vario...

    Authors: Zhitao Zhang, Yanzhen Han, Guangxin Sun, Xiaohong Liu, Xiaoyan Jia and Xiangjun Yu

    Citation: Cellular & Molecular Biology Letters 2019 24:13

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  36. Content type: Short report

    The tumor susceptibility gene 101 (TSG101) is closely associated with various tumor types, but its role in the pathogenesis of renal cell carcinoma (RCC) is still unknown. This study used RNA interference to s...

    Authors: Chen Xu and Junhua Zheng

    Citation: Cellular & Molecular Biology Letters 2019 24:7

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  37. Content type: Research

    To investigate the anti-tumor effects and the mechanism of the compound 13-chlorine-3, 15-dioxy-gibberellic acid methyl ester (GA-13315) in lung adenocarcinoma in vitro and in vivo.

    Authors: Lin Xie, Yajuan Chen, Jingbo Chen, Hongbin Zhang, Yedan Liao, Yonghong Zhou, Ling Zhou and Chen Qing

    Citation: Cellular & Molecular Biology Letters 2019 24:6

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  38. Content type: Short report

    Extracellular vesicles are small vesicles that contain cytoplasmic and membrane components from their paternal cells. They enter target cells through uptake to transfer their biological cargo. In this study, w...

    Authors: Martyna Durak-Kozica, Zbigniew Baster, Karol Kubat and Ewa Stępień

    Citation: Cellular & Molecular Biology Letters 2018 23:57

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