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  1. During aging and after traumatic injuries, cartilage and bone cells are exposed to various pathophysiologic mediators, including reactive oxygen species (ROS), damage-associated molecular patterns, and proinfl...

    Authors: Jana Riegger, Astrid Schoppa, Leonie Ruths, Melanie Haffner-Luntzer and Anita Ignatius
    Citation: Cellular & Molecular Biology Letters 2023 28:76
  2. Osteoarthritis (OA), a common joint disorder with articular cartilage degradation as the main pathological change, is the major source of pain and disability worldwide. Despite current treatments, the overall ...

    Authors: Zehao Zhang, Sheng Zhao, Zhaofeng Sun, Chuanxing Zhai, Jiang Xia, Caining Wen, Yuge Zhang and Yuanmin Zhang
    Citation: Cellular & Molecular Biology Letters 2023 28:75
  3. Cardiomyocyte death induced by autophagy inhibition is an important cause of cardiac dysfunction. In-depth exploration of its mechanism may help to improve cardiac dysfunction. In our previous study, we found ...

    Authors: Xiaoyan Zhi, Shu Shi, Yang Li, Mingxia Ma, Yaolin Long, Chen Li, Haihu Hao, Huirong Liu, Xiaohui Wang and Li Wang
    Citation: Cellular & Molecular Biology Letters 2023 28:74
  4. Cancer remains a significant global health challenge, necessitating the exploration of novel and more precise therapeutic options beyond conventional treatments. In this regard, clustered regularly interspaced...

    Authors: Mingxia Wang, Menghui Chen, Xia Wu, Xinbo Huang and Bo Yu
    Citation: Cellular & Molecular Biology Letters 2023 28:73
  5. In recent years, N6-methyladenosine (m6A) methylation modification of mRNA has been studied extensively. It has been reported that m6A determines mRNA fate and participates in many cellular functions and reaction...

    Authors: Huan Li, Jun Zhao, Hao Deng, YuCheng Zhong, Mian Chen, LinSheng Chi, GuoQun Luo, Cong Cao, Cong Yu, Honghai Liu and Xinzong Zhang
    Citation: Cellular & Molecular Biology Letters 2023 28:72
  6. Mechanical pressure overload and other stimuli often contribute to heart hypertrophy, a significant factor in the induction of heart failure. The UDP-glucose ceramide glycosyltransferase (UGCG) enzyme plays a ...

    Authors: Shengyu Cui, Xutao Zhang, Yuhua Li, Shan Hu, Bing Wu, Zhao Fang, Jixian Gao, Ming Li, Haoliang Wu, Bo Tao, Hao Xia and Lin Xu
    Citation: Cellular & Molecular Biology Letters 2023 28:71
  7. Chronic apical periodontitis is a prevalent oral disease characterized by bone loss, and its underlying mechanisms remain unclear. This study aimed to investigate the role and mechanism of the serine protease ...

    Authors: Tingting Jia, Fang Yuan, Jingqiao Tao, Gang Wang, Xianhua Zhang, Bin Zhang and Hongbo Li
    Citation: Cellular & Molecular Biology Letters 2023 28:70
  8. Authors: Yanchun Li, Bing Xu, Xueying Ren, Luyang Wang, Yaqing Xu, Yefeng Zhao, Chen Yang, Chen Yuan, Huanjuan Li, Xiangmin Tong, Ying Wang and Jing Du
    Citation: Cellular & Molecular Biology Letters 2023 28:69

    The original article was published in Cellular & Molecular Biology Letters 2022 27:81

  9. Desmocollin-1 (DSC1) is a desmosomal transmembrane glycoprotein that maintains cell-to-cell adhesion. DSC1 was previously associated with lymph node metastasis of luminal A breast tumors and was found to incre...

    Authors: Petr Lapcik, Petr Sulc, Lucia Janacova, Katerina Jilkova, David Potesil, Pavla Bouchalova, Petr Müller and Pavel Bouchal
    Citation: Cellular & Molecular Biology Letters 2023 28:68
  10. Prenatal infection has been implicated in the development of neuropsychiatric disorders in children. We hypothesised that exposure to lipopolysaccharide during prenatal development could induce anxiety-like be...

    Authors: Chie-Pein Chen, Pei-Chun Chen, Yu-Ling Pan and Yi-Chao Hsu
    Citation: Cellular & Molecular Biology Letters 2023 28:67
  11. Endothelial dysfunction and deregulated microRNAs (miRNAs) participate in the development of sepsis and are associated with septic organ failure and death. Here, we explored the role of miR-15b-5p on inflammat...

    Authors: Elisa Martino, Nunzia D’Onofrio, Anna Balestrieri, Luigi Mele, Celestino Sardu, Raffaele Marfella, Giuseppe Campanile and Maria Luisa Balestrieri
    Citation: Cellular & Molecular Biology Letters 2023 28:66
  12. Peripheral nerve damage causes neuroinflammation, which plays a critical role in establishing and maintaining neuropathic pain (NeP). The mechanisms contributing to neuroinflammation remain poorly elucidated, ...

    Authors: Jingyi Du, Nan Cheng, Yifan Deng, Ping Xiang, Jianfen Liang, Zhenye Zhang, Ziqing Hei and Xiang Li
    Citation: Cellular & Molecular Biology Letters 2023 28:65
  13. In plants, RNase III Dicer-like proteins (DCLs) act as sensors of dsRNAs and process them into short 21- to 24-nucleotide (nt) (s)RNAs. Plant DCL4 is involved in the biogenesis of either functional endogenous ...

    Authors: Paola Leonetti, Arianna Consiglio, Dennis Arendt, Ralph Peter Golbik, Luisa Rubino, Torsten Gursinsky, Sven-Erik Behrens and Vitantonio Pantaleo
    Citation: Cellular & Molecular Biology Letters 2023 28:64
  14. Nitrogen (N), phosphorus (P) and potassium (K) are critical macronutrients in crops, such that deficiency in any of N, P or K has substantial effects on crop growth. However, the specific commonalities of plan...

    Authors: Ying Fu, Annaliese S. Mason, Maolin Song, Xiyuan Ni, Lei Liu, Jianghua Shi, Tanliu Wang, Meili Xiao, Yaofeng Zhang, Donghui Fu and Huasheng Yu
    Citation: Cellular & Molecular Biology Letters 2023 28:63
  15. Bladder cancer (BLCA) is a malignancy that frequently metastasizes and leads to poor patient prognosis. It is essential to understand the molecular mechanisms underlying the progression and metastasis of BLCA ...

    Authors: Xiangqin Kuang, Zhuojun Zhang, Difeng Li, Wenhao Bao, Jinyuan Pan, Ping Zhou, Han Chen, Zhiqing Gao, Xiaoyi Xie, Chunxiao Yang, Ge Zhu, Zhongqiu Zhou, Ruiming Tang, Zhengfu Feng, Lihuan Zhou, Xiaoli Feng…
    Citation: Cellular & Molecular Biology Letters 2023 28:62
  16. Amphibian derived pro-healing peptides as molecular probes might provide a promising strategy for development of drug candidates and elucidation of cellular and molecular mechanisms of skin wound healing. A no...

    Authors: Chao Li, Zhe Fu, Tao Jin, Yixiang Liu, Naixin Liu, Saige Yin, Zhuo Wang, Yubing Huang, Yinglei Wang, Yingxuan Zhang, Jiayi Li, Yutong Wu, Li He, Jing Tang, Ying Wang and Xinwang Yang
    Citation: Cellular & Molecular Biology Letters 2023 28:61
  17. Sebaceous glands (SGs) synthesize and secret sebum to protect and moisturize the dermal system via the complicated endocrine modulation. Dysfunction of SG are usually implicated in a number of dermal and infla...

    Authors: Tao Yang, Renyi Hei, Xiaosong Li, Tianhua Ma, Yifen Shen, Chao Liu, Wen He, Lin Zhu, Yongchun Gu, Yanping Hu, Wenbin Wei and Yihang Shen
    Citation: Cellular & Molecular Biology Letters 2023 28:60
  18. The dynamics of phosphatidylserine in the plasma membrane is a tightly regulated feature of eukaryotic cells. Phosphatidylserine (PS) is found preferentially in the inner leaflet of the plasma membrane. Disrup...

    Authors: Eimina Dirvelyte, Daina Bujanauskiene, Evelina Jankaityte, Neringa Daugelaviciene, Ugne Kisieliute, Igor Nagula, Rima Budvytyte and Urte Neniskyte
    Citation: Cellular & Molecular Biology Letters 2023 28:59
  19. One of the factors that affect the progression of melanoma is the tumor microenvironment, which consists of cellular elements, extracellular matrix, acidification, and a hypoxic state. Adipocytes are one of th...

    Authors: Aleksandra Simiczyjew, Justyna Wądzyńska, Katarzyna Pietraszek-Gremplewicz, Magdalena Kot, Marcin Ziętek, Rafał Matkowski and Dorota Nowak
    Citation: Cellular & Molecular Biology Letters 2023 28:58
  20. The preference for glucose oxidative mode has crucial impacts on various physiological activities, including determining stem cell fate. External mechanical factors can play a decisive role in regulating criti...

    Authors: Zijie Zhang, Shuyue Cui, Yajing Fu, Jixiao Wang, Jiani Liu and Fulan Wei
    Citation: Cellular & Molecular Biology Letters 2023 28:57
  21. Focal adhesions (FAs) are integrin-containing, multi-protein structures that link intracellular actin to the extracellular matrix and trigger multiple signaling pathways that control cell proliferation, differ...

    Authors: Marija Lončarić, Nikolina Stojanović, Anja Rac-Justament, Kaatje Coopmans, Dragomira Majhen, Jonathan D. Humphries, Martin J. Humphries and Andreja Ambriović-Ristov
    Citation: Cellular & Molecular Biology Letters 2023 28:56
  22. Hepatic ischemia–reperfusion injury (IRI) in donation after cardiac death (DCD) donors is a major determinant of transplantation success. Endoplasmic reticulum (ER) stress plays a key role in hepatic IRI, with...

    Authors: Pengpeng Yue, Xiaoyan Lv, Jian You, Yongkang Zou, Jun luo, Zhongshan Lu, Hankun Cao, Zhongzhong Liu, Xiaoli Fan and Qifa Ye
    Citation: Cellular & Molecular Biology Letters 2023 28:55
  23. The AMPA-type ionotropic glutamate receptor mediates fast excitatory neurotransmission in the brain. A variety of auxiliary subunits regulate its gating properties, assembly, and trafficking, but it is unknown...

    Authors: Chenlu Yu, Hendrik F. P. Runge, Antara Mukhopadhyay, Gerd Zolles and Maximilian H. Ulbrich
    Citation: Cellular & Molecular Biology Letters 2023 28:54
  24. Fibulin-like extracellular matrix protein 2 (EFEMP2) has been reported to be related to the progression of various cancers. We have previously reported that EFEMP2 was highly expressed in ovarian cancer and wa...

    Authors: Xin Shen, Xuli Jin, Shuang Fang and Jie Chen
    Citation: Cellular & Molecular Biology Letters 2023 28:53
  25. Improvements in treatment and chemotherapy have increased the survival rate of osteosarcoma, but overall efficacy remains low, highlighting the need for new gene therapy methods. Clustered regularly interspace...

    Authors: Yawei Hu, Hao Zhang, Zengfeng Guo, Jianhua Zhou, Wang Zhang, Ming Gong and Jiawen Wu
    Citation: Cellular & Molecular Biology Letters 2023 28:52
  26. The NOD-like receptor protein 3 (NLRP3) inflammasome is a protein complex that regulates innate immune responses by activating caspase-1 and the inflammatory cytokines interleukin (IL)-1β and IL-18. Multiple s...

    Authors: Ying Chen, Xingyan Ye, Germaine Escames, Wangrui Lei, Xin Zhang, Meng Li, Tong Jing, Yu Yao, Zhenye Qiu, Zheng Wang, Darío Acuña-Castroviejo and Yang Yang
    Citation: Cellular & Molecular Biology Letters 2023 28:51
  27. Energy metabolism disorder or insufficient energy supply during incubation will affect the development and survival of avian embryos. Especially, β-oxidation could not provide the continuous necessary energy f...

    Authors: Heng Wang, Wenqi Liang, Xuyang Wang, Yuchun Zhan, Wence Wang, Lin Yang and Yongwen Zhu
    Citation: Cellular & Molecular Biology Letters 2023 28:50
  28. Transfer (t)RNA-derived small RNA (tsRNA), generated from precursor or mature tRNA, is a new type of small non-coding RNA (sncRNA) that has recently been shown to play a vital role in human cancers. However, i...

    Authors: Rui Zhao, Zhenming Yang, Bo Zhao, Wenjing Li, Yaohui Liu, Xiaoxue Chen, Jing Cao, Jiarui Zhang, Yan Guo, Licheng Xu, Jinpeng Wang, Yanan Sun, Ming Liu and Linli Tian
    Citation: Cellular & Molecular Biology Letters 2023 28:49
  29. Pulmonary fibrosis is a major category of end-stage changes in lung diseases, characterized by lung epithelial cell damage, proliferation of fibroblasts, and accumulation of extracellular matrix. Peroxiredoxin...

    Authors: Hu-Nan Sun, Chen-Xi Ren, Dong Hun Lee, Wei-Hao Wang, Xiao-Yu Guo, Ying-Ying Hao, Xiao-Ming Wang, Hui-Na Zhang, Wan-Qiu Xiao, Nan Li, Jie Cong, Ying-Hao Han and Taeho Kwon
    Citation: Cellular & Molecular Biology Letters 2023 28:48
  30. Resistance to immune checkpoint inhibitor (ICI) therapy narrows the efficacy of cancer immunotherapy. Although 4-1BB is a promising drug target as a costimulatory molecule of immune cells, no 4-1BB agonist has...

    Authors: Lian-sheng Cheng, Min Zhu, Yan Gao, Wen-ting Liu, Wu Yin, Pengfei Zhou, Zhongliang Zhu, Liwen Niu, Xiaoli Zeng, Dayan Zhang, Qing Fang, Fengrong Wang, Qun Zhao, Yan Zhang and Guodong Shen
    Citation: Cellular & Molecular Biology Letters 2023 28:47
  31. For cancer therapy, the identification of both selective autophagy targets and small molecules that specifically regulate autophagy is greatly needed. Heat shock protein 70 (Hsp70) is a recently discovered BH3...

    Authors: Ting Song, Fangkui Yin, Ziqian Wang, Hong Zhang, Peng Liu, Yafei Guo, Yao Tang and Zhichao Zhang
    Citation: Cellular & Molecular Biology Letters 2023 28:46
  32. CD36 has been identified as a potential therapeutic target both in leukemic cells and in the tumor immune microenvironment. In acute myeloid leukemia (AML), we found that APOC2 acts with CD36 to promote leukem...

    Authors: Yiting Meng, Mateusz Pospiech, Atham Ali, Ritu Chandwani, Mary Vergel, Sandra Onyemaechi, George Yaghmour, Rong Lu and Houda Alachkar
    Citation: Cellular & Molecular Biology Letters 2023 28:45
  33. Oncologic patients are subjected to four major treatment types: surgery, radiotherapy, chemotherapy, and immunotherapy. All nonsurgical forms of cancer management are known to potentially violate the structura...

    Authors: Paweł Uruski, Julia Matuszewska, Aleksandra Leśniewska, Daniel Rychlewski, Arkadiusz Niklas, Justyna Mikuła-Pietrasik, Andrzej Tykarski and Krzysztof Książek
    Citation: Cellular & Molecular Biology Letters 2023 28:44
  34. Although metabolomics continues to expand in many domains of research, methodological issues such as sample type, extraction and analytical protocols have not been standardized, impeding proper comparison betw...

    Authors: Maryne Lepoittevin, Quentin Blancart-Remaury, Thomas Kerforne, Luc Pellerin, Thierry Hauet and Raphael Thuillier
    Citation: Cellular & Molecular Biology Letters 2023 28:43
  35. Renal ischemia–reperfusion injury (IRI) is one reason for renal transplantation failure. Recent studies have shown that mitochondrial dynamics is closely related to IRI, and that inhibition or reversal of mito...

    Authors: Wenbo Yang, Xiaoli Li, Liujie He, Shuyang Zhu, Shicong Lai, Xiaopeng Zhang, Zixiong Huang, Biyue Yu, Chunping Cui and Qiang Wang
    Citation: Cellular & Molecular Biology Letters 2023 28:42
  36. The plasmid vector platform is the most commonly used vector for the expression of the versatile CRISPR-Cas technique and the promoter is a crucial element for the expression vector, thus profiling the impact ...

    Authors: Jinhe Li, Qinchun Liang, HuaPing Zhou, Ming Zhou and Hongxin Huang
    Citation: Cellular & Molecular Biology Letters 2023 28:41
  37. Deer antlers are the only known mammalian structure that undergoes full regeneration. In addition, it is peculiar because when growing, it contains vascularized cartilage. The differentiation of antler stem ce...

    Authors: Xunsheng Li, Wanwan Shi, Guanning Wei, Jinpeng Lv, Datao Wang, Baorui Xing, Jue Zhou, Jianwei Zhao and Hongmei Sun
    Citation: Cellular & Molecular Biology Letters 2023 28:40
  38. Tissues need to regenerate to restore function after injury. Yet, this regenerative capacity varies significantly between organs and between species. For example, in the heart, some species retain full regener...

    Authors: Pearlyn Jia Ying Toh, Marius Sudol and Timothy Edward Saunders
    Citation: Cellular & Molecular Biology Letters 2023 28:39
  39. Prostate cancer is one of the more heterogeneous tumour types. In recent years, with the rapid development of single-cell sequencing and spatial transcriptome technologies, researchers have gained a more intui...

    Authors: Xudong Yu, Ruijia Liu, Wenfeng Gao, Xuyun Wang and Yaosheng Zhang
    Citation: Cellular & Molecular Biology Letters 2023 28:38
  40. Metabolic reprogramming is a well-known feature of cancer that allows malignant cells to alter metabolic reactions and nutrient uptake, thereby promoting tumor growth and spread. It has been discovered that no...

    Authors: Amir Safi, Mohammadreza Saberiyan, Mohammad-Javad Sanaei, Samaneh Adelian, Fateme Davarani Asl, Mahsa Zeinaly, Mahdi Shamsi and Reza Ahmadi
    Citation: Cellular & Molecular Biology Letters 2023 28:37
  41. Oral squamous cell carcinomas are one of the most common cancers worldwide with aggressive behavior and poor prognosis. Reactive oxygen species (ROS) are associated with cancer and cause various types of regul...

    Authors: Leilei Wang, Chuan Wang, Xuan Li, Zhuoying Tao, Wangyong Zhu, Yuxiong Su and Wing Shan Choi
    Citation: Cellular & Molecular Biology Letters 2023 28:36
  42. Heart failure is a common complication of sepsis with a high mortality rate. It has been reported that melatonin can attenuate septic injury due to various properties. On the basis of previous reports, this st...

    Authors: Wencheng Di, Zhenxiao Jin, Wangrui Lei, Qiong Liu, Wenwen Yang, Shaofei Zhang, Chenxi Lu, Xiaoling Xu, Yang Yang and Huadong Zhao
    Citation: Cellular & Molecular Biology Letters 2023 28:35
  43. Breast cancer (BC) is a common threat to women. The continuous activation of nuclear factor kappa B (NF-κB) signaling pathway contributes to the development of BC. This study aimed to investigate the role of a...

    Authors: Wenfang Zheng, Xuehui Wang, Yunhe Yu, Changle Ji and Lin Fang
    Citation: Cellular & Molecular Biology Letters 2023 28:34
  44. Hepatocellular carcinoma (HCC) is considered one of the greatest challenges to human life and is the most common form of liver cancer. Treatment of HCC depends on chemotherapy, radiotherapy, surgery, and immun...

    Authors: Mehrdad Hashemi, Eisa Sabouni, Parham Rahmanian, Maliheh Entezari, Mahsa Mojtabavi, Behnaz Raei, Mohammad Arad Zandieh, Mitra Behroozaghdam, Sepideh Mirzaei, Kiavash Hushmandi, Noushin Nabavi, Shokooh Salimimoghadam, Jun Ren, Mohsen Rashidi, Rasoul Raesi, Afshin Taheriazam…
    Citation: Cellular & Molecular Biology Letters 2023 28:33
  45. N6-methyladenosine (m6A) has been shown to participate in various essential biological processes by regulating the level of target genes. However, the function of m6A modification mediated by KIAA1429 [alias vir....

    Authors: Xiaomin Chen, Tiange Lu, Yiqing Cai, Yang Han, Mengfei Ding, Yurou Chu, Xiangxiang Zhou and Xin Wang
    Citation: Cellular & Molecular Biology Letters 2023 28:32
  46. Metastasis is the leading cause of death among patients with colorectal cancer (CRC). Therefore, it is important to explore the molecular mechanisms of metastasis to develop effective therapeutic targets for C...

    Authors: Jiaxian Zhu, Ting Long, Lingfang Gao, Yan Zhong, Ping Wang, Xiaoyan Wang, Zuguo Li and Zhiyan Hu
    Citation: Cellular & Molecular Biology Letters 2023 28:31
  47. Accurate assessment of the carcinogenic potential of oral mucosal diseases can significantly reduce the prevalence of oral cancer. We speculate that precancerous stem cells (pCSCs) arise during the evolution o...

    Authors: Shan Wang, Liu Ying, Shu-Yi Yu, Jie Bai and Chunbo Hao
    Citation: Cellular & Molecular Biology Letters 2023 28:30
  48. Bladder cancer (BC) is a clinical challenge worldwide with late clinical presentation, poor prognosis, and low survival rates. Traditional cystoscopy and tissue biopsy are routine methods for the diagnosis, pr...

    Authors: Shijie Li, Kerong Xin, Shen Pan, Yang Wang, Jianyi Zheng, Zeyu Li, Xuefeng Liu, Bitian Liu, Zhenqun Xu and Xiaonan Chen
    Citation: Cellular & Molecular Biology Letters 2023 28:28
  49. Innate immune responses play essential roles in skeletal muscle recovery after injury. Programmed cell death protein 1 (PD-1) contributes to skeletal muscle regeneration by promoting macrophage proinflammatory...

    Authors: Shuzhao Zhuang, Aaron Russell, Yifan Guo, Yingying Xu and Weihua Xiao
    Citation: Cellular & Molecular Biology Letters 2023 28:27

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