Fig. 3

The effect of miR-378 on the migration and invasion abilities of colon cancer cells. a, b The effect of miR-378 mimics on the migration (a) and invasion (b) of SW480 and HCT-116 cells determined using Transwell plates. c Quantitative RT-PCR was used to measure the mRNA levels of three EMT markers, e-Cadherin, vimentin and a-SMA, in miR-378 mimics transfected SW480 cells. d Western blot was used to measure the protein levels of these EMT makers in SW480 cells transfected with miR-378 mimics. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001