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Fig. 6 | Cellular & Molecular Biology Letters

Fig. 6

From: SFRP2 enhances the osteogenic differentiation of apical papilla stem cells by antagonizing the canonical WNT pathway

Fig. 6

SFRP2 rescued the impaired osteogenic differentiation potential of WNT1 in SCAPs. a Schematic representation of the transwell culture. b Transwell culture results showed that overexpression of SFRP2 could partially inhibit the reduction in ALP activity by WNT1. c Alizarin Red staining and (d) quantitative analysis of calcium concentration results showed that the overexpression of SFRP2 could partially inhibit the reduction in mineralization by WNT1. Vector 1: empty vector as the control of SFRP2. Vector2: empty vector as the control of HA-WNT1. Student’s t test was performed to determine statistical significance. All error bars represent SD (n = 3). **p ≤ 0.01. (sigma unit: unit of measurement for ALP activity)

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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