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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: PIWI-like protein, HIWI2 is aberrantly expressed in retinoblastoma cells and affects cell-cycle potentially through OTX2

Fig. 3

HIWI2 silencing affects the proliferation of Y79 cells. a – Histogram shows the changes in the cell cycle distribution of Si-HIWI2 Y79 cells. b – Bar graph represents the percentage of cells distributed among various phases of the cell cycle in HIWI2 knockdown. c – Western blot showing the expression of PCNA upon HIWI2 knockdown in Y79 cells. Bar graph represents the percentage of PCNA expression. d – Western blot showing the expression of p16 upon HIWI2 knockdown in Y79 cells. The bar graph represents the percentage of p16 expression. Student’s t-test was used for statistical analysis. *p < 0.05, **p < 0.01 and ***p < 0.001 were considered as statistically significant

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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