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Table 4 Distribution of APOE genotypes and allele frequencies according to aSAH subtypes

From: Apolipoprotein E polymorphism and the risk of aneurysmal subarachnoid hemorrhage in a South Indian population

Variable Case ε 2/ ε2 P ε 2/ ε3 P ε 2/ ε4 P ε 3/ ε3 P ε 3/ ε4 P ε 4/ ε4 P ε 2 Vs ε3 (P) ε 4 Vs ε3 (P)
Total 200 2   18   1   134   45   0    
Site of Aneurysm
 ACOM 86 0 0.62 7 0.86 1 0.69 57 0.89 21 0.78 0 0.69 0.61 0.57
 PCOM 12 1 0.09 2 0.42 0 0.15 5 0.26 4 0.51 0 0.15 0.03 0.31
 ICA 36 0 0.82 2 0.92 0 0.33 30 0.61 4 0.18 0 0.33 0.26 0.12
 MCA 37 1 0.42 4 0.75 0 0.44 24 0.82 8 0.92 0 0.44 0.44 0.65
 Multiple 22 0 0.71 3 0.53 0 0.29 13 0.73 6 0.81 0 0.29 0.74 0.65
 Basilar top 7 0 0.29 0 0.82 0 0.11 5 0.91 2 0.69 0 0.11 0.69 0.81
Size of Aneurysm
 Small (<15 mm) 159 1 0.70 14 0.95 1 0.87 109 0.89 34 0.83 0 0.89 0.81 0.81
 Large (15-25 mm) 37 1 0.50 3 0.86 0 0.45 22 0.68 11 0.46 0 0.45 0.67 0.39
 Giant (>25 mm) 4 0 0.17 1 037 0 0.06 3 0.88 0 0.95 0 0.06 0.50 0.61
WFNS Grade
 Grade I 91 1 1 10 0.62 1 0.73 57 0.73 22 0.80 0 0.73 0.49 0.64
 Grade II 42 0 0.99 6 0.35 0 0.42 30 0.80 5 0.20 0 0.42 0.68 0.16
 Grade III 51 1 0.56 0 0.11 0 0.48 36 0.83 13 0.77 0 0.48 0.14 0.77
 Grade IV 16 0 0.57 2 0.67 0 0.16 11 0.94 5 0.54 0 0.16 0.99 0.67
Male 77 1 0.50 10 0.37 1 0.62 51 0.95 14 0.52 0 0.62 0.27 0.62
Female 123 1 0.85 8 0.46 0 0.70 83 0.96 31 0.66 0 0.81 0.35 0.76
Hypertension (+) 109 1 0.94 9 0.83 0 0.75 74 0.94 25 0.94 0 0.75 0.71 0.96
Diabetes mellitus (+) 71 0 0.82 5 0.63 1 0.46 51 0.74 14 0.69 0 0.55 0.30 0.57
Alcohol (+) 57 1 0.64 10 0.11 1 0.37 33 0.54 12 0.85 0 0.55 0.04 0.85
Smoking (+) 58 0 0.80 8 0.34 1 0.38 38 0.92 11 0.64 0 0.52 0.44 0.78