Fig. 2

Knockdown of SNHG8 inhibits cell proliferation and clonogenic potential in GT38 cells. a The specific shRNA sh-SNHG8 decreased the SNHG8 level by up to 57% in GT38 cells. **p < 0.01. b The results of 3 consecutive days of cell viability assessments for GT38 cells with (KD group) or without (NC group) specific shRNA transfections and blank control cells (CON group). c GT38 cells with (KD group) or without (NC group) specific shRNA transfections and blank control cells (CON group) were subjected to colony formation assays. After crystal violet staining, colonies were visually observed. d Counting of colonies showed that colony numbers had significantly decreased in the KD group. **p < 0.01 compared with NC group. CON, blank control cells without transfection; NC, negative control; KD, SNHG8 knockdown