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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: ClC-2 knockdown prevents cerebrovascular remodeling via inhibition of the Wnt/β-catenin signaling pathway

Fig. 3

ClC-2 downregulation prevented AngII-induced HBVSMC migration and invasion. a HBVSMCs transfected with ClC-2 siRNA (siClC-2; 20 nM) or negative siRNA (negative; 20 nM) were subjected to angiotensin II (AngII) treatment (10− 7 M). The wound healing assay was performed. Representative images are shown (× 100). b The quantification results for the wound closure. c HBVSMC migration was examined via transwell analysis. Representative images are shown (× 100). d The columns represent the relative numbers of invasive cells. **p < 0.01 vs. control, ##p < 0.01 vs. AngII alone, n = 6

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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