Fig. 2
From: LAMP3 plays an oncogenic role in osteosarcoma cells partially by inhibiting TP53
LAMP3 regulated cell apoptosis in osteosarcoma (OS) cells. a and c – Apoptosis assay results showing that the percentage of apoptotic cells increased after inhibition of LAMP3 compared with the control. E – The apoptotic rate significantly decreased when LAMP3 was overexpressed compared with the control cells. b and d – Western blots showing the upregulated expression of cleaved-caspase-3 (b) and TP53 (d) after knockdown of LAMP3 in either OS-732 or U2OS cells. f – Representative example of the downregulated expression of cleaved-caspase-3 and TP53 at the protein level with exogenous LAMP3 expression. *p < 0.05, **p < 0.01, ***p < 0.001, n = 3