Fig. 2
![Fig. 2](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs11658-018-0114-0/MediaObjects/11658_2018_114_Fig2_HTML.png)
The effect of GYY4137 on the hormone levels in the rat plasma related to bone metabolism in the OVX model. The levels of a alkaline phosphatase, b osteocalcin, c calcitonin, d parathyrin and e leptin were assessed in all four groups of rats. *p < 0.05 vs. sham-vehicle group; **p < 0.01 vs. sham-vehicle group; #p < 0.05 vs. OVX-vehicle group; ##p < 0.01 vs. OVX-vehicle. OVX-vehicle: ovarectomized rats treated with vehicle; OVX-ALEN: ovarectomized rats treated with alendronate sodium; OVX-GYY: ovarectomized rats treated with GYY4137