Fig. 6

Effect of IL-33 neutralization on LPS-induced expression of MMP2 and MMP9 in NR8383 cells. (a and b) Levels of MMP2 (a) and MMP9 (b) in the medium at 24 h after LPS treatment with or without adding IL-33 antibodies to NR8383 cells. (c-e) mRNA (c and d) and protein (e) levels of MMP2 and MMP9 at 24 h after LPS treatment with or without adding IL-33 antibodies to NR8383 cells. Data are shown as means±SD (three independent repeats). The relative mRNA or protein level was normalized to the IgG/PBS group. Two-way ANOVA was used in the statistical analyses. * p < 0.05, ** p < 0.01, *** p < 0.001