Identification and validation of NOLC1 as a potential target for enhancing sensitivity in multidrug resistant non-small cell lung cancer cells

Table 1 Cytotoxicity of drugs in A549/DDP and A549/MDR cells

Drug	A549/DDP IC50 (μg/ml)	A549/MDR IC50 (μg/ml)	RI
5-fluorouracil	28.17	130.06	4.62
Paclitaxel	4.65	82.82	17.83
Mitomycin	1.43	8.67	6.04
Vinorelbine Tartrate	6.09	12.39	2.04
Cisplatin	5.00	33.51	6.70
Gemcitabine Hydrochloride	1.08	19.01	17.59

IC50 50% inhibitory concentration, RI resistance index, DDP Cisplatin, MDR multidrug resistance

ISSN: 1689-1392