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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion

Fig. 3

The effect of CDKL1 knockdown on the proliferation, cell cycle distribution and apoptosis of NB cells in vitro. a Analysis of cell viability of siCDKL1-transfected cells based on the MTT assay. b Photomicrographs and statistical analyses of colonies of SH-SY5Y cells after transfection with siCDKL1 or NC. c The effect of CDKL1 knockdown on the cell cycle profile of SH-SY5Y cells by FACS. The percentage of cells in G0/G1, S and G2/M phases are shown. d Lentivirus-infected SH-SY5Y cells were analyzed using flow cytometry analysis for positive annexin V–APC and 7-AAD staining . Data are presented as means ± SD. **p < 0.01, ***p < 0.001 vs. NC

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