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Fig. 2 | Cellular & Molecular Biology Letters

Fig. 2

From: Hypoxia-associated circDENND2A promotes glioma aggressiveness by sponging miR-625-5p

Fig. 2

CircDENND2A contributes to the hypoxia-induced migration and invasion of glioma cells. a and b Left: Representative images from wound healing assays or Transwell assays in normoxic or hypoxic U87MG (a) and A172 (b) cells with or without knockdown of circDENND2A. Scale bar, 100 μm. Right: Percentage of wound closure or numbers of invasive cells at 48 h after treatment. c and d Left: Representative images from wound healing assays or Transwell assays in U87MG cells with or without overexpression of circDENND2A. Scale bar, 100 μm. Right: Percentage of wound closure or numbers of invasive cells at 48 h after treatment. Data are shown as mean ± SD (three independent repeats). * p < 0.05, ** p < 0.01, *** p < 0.001

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