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Table 4 Effects of hyperthermia on changes in the concentration of dFdC and its metabolites

From: Concentration changes in gemcitabine and its metabolites after hyperthermia in pancreatic cancer cells assessed using RP-HPLC

 

dFdC (μg/ml)

dFdU (μg/ml)

dFdCTP (μg/ml)

37 °C

1.02

2.86

3.24

0.91

3.65

3.25

1.03

3.41

3.33

0.90

2.91

2.89

1.02

3.15

3.81

Average value

0.97

3.19

3.30

Standard deviation

0.063

0.33

0.34

41 °C

1.12

2.29

4.17

0.97

2.57

3.92

0.70

2.33

4.98

0.94

2.52

3.37

0.66

2.31

3.68

Average value

0.88

2.40

4.02

Standard deviation

0.19

0.13

0.61

43 °C

0.82

1.43

4.79

0.68

1.46

4.67

0.64

1.14

4.76

0.69

1.15

4.81

0.55

1.52

4.46

Average value

0.67

1.34

4.70

Standard deviation

0.099

0.18

0.14