Fig. 6

Adipor2 is an effector of miR-19a-3p’s role in inducing cerebral ischemic injury. a, b, Glucose uptake (a) and lactate production (b) in neuronal cells transfected with siRNA-targeting Adipor2 either alone or in combination with anti-miR-19a-3p inhibitor. All data are representative of three independent experiments and were expressed as means ± SD. (**P < 0.01 vs. control group, #P < 0.05 vs. si- ADIPOR2 group). c, Model summarizing the major findings of the current study highlighting how elevated miR-19a-3p expression during IR and OGD can result in impaired glucose metabolism and apoptosis by targeting Adipor2