Fig. 2

MSCs alleviated pancreatic impairment and decreased BBB permeability in SAP rats. a H&E staining of the pancreas (× 200). No obvious pathological changes were observed in the control group, while edema, hemorrhage, necrotic acini and the infiltration of inflammatory cells were observed in the SAP group. The pancreatic impairment in the SAP+MSCs group was milder than that in the SAP group. b Pancreatic pathological scores. c Brain dry/wet ratio calculation. d The results of the Evans Blue assay. ***p < 0.001, ****p < 0.0001)