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Fig. 2 | Cellular & Molecular Biology Letters

Fig. 2

From: MicroRNA-5195-3p enhances the chemosensitivity of triple-negative breast cancer to paclitaxel by downregulating EIF4A2

Fig. 2

MiR-5195-3p enhanced the paclitaxel sensitivity of breast cancer cells. a Synthesized miR-5195-3p mimics were transfected into paclitaxel-resistant MCF-7/PTX and MDA-MB-231/PTX cells. MiR-5195-3p expression was measured using quantitative real-time PCR. b and c CCK-8 assay was performed to determine the cell sensitivity to paclitaxel of MCF-7/PTX and MDA-MB-231/PTX cells. d The 50% inhibitory concentration (IC50) value of paclitaxel in MCF-7/PTX and MDA-MB-231/PTX cells transfected with mimics or miR-NC. ***p < 0.001 vs. miR-NC

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