Fig. 6
From: MiR-135-5p promotes osteoblast differentiation by targeting HIF1AN in MC3T3-E1 cells
MiR-135-5p promotes osteoblast differentiation of MC3T3-E1 cells by targeting HIF1AN after incubation in DM supplemented with BMP2 for 14 days. The protein levels of Runx2, OPN, OCN and OSX in MC3TC-E1 cells subjected to the indicated treatments were determined using western blotting. ***p < 0.001 vs. control; ###p < 0.001 vs. pcDNA; △p < 0.05, △△p < 0.01 vs. pcDNA-HIF1AN + miR-135-5p