Fig. 4

MiR-653-5p inhibition repressed prostate cancer cell proliferation and invasion. a The relative miR-653-5p expression in prostate cancer cell lines was examined using quantitative real-time PCR (n = 5, *p < 0.05 versus RWPE-1). b PPC-1 and PC-3 cells were transfected with miR-653-5p mimics, inhibitor or NC mimics/inhibitor for 48 h. The relative miR-653-5p expression was determined using quantitative real-time PCR. c Cell proliferation was measured with the CCK-8 assay after transfection with miR-653-5p mimics, inhibitor or NC mimics/inhibitor for 48 h. d PPC-1 and PC-3 cells were transfected with miR-653-5p mimics, inhibitor, or NC mimics/inhibitor for 48 h. The transwell Matrigel invasion assay to determine cell invasion ran for 24 h (n = 5, *p < 0.05)