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Table 2 The effect of miR-637 on blood lipids in ApoE knockout mice (\( \overline{\mathrm{x}}\kern0.5em \pm \kern0.5em \mathrm{s} \))

From: Downregulation of miR-637 promotes vascular smooth muscle cell proliferation and migration via regulation of insulin-like growth factor-2

GroupAG-NCAGAN-NCAN
Body weight (g)26.48 ± 2.5428.37 ± 2.8827.52 ± 2.3328.12 ± 2.42
TG (mmol/l)2.46 ± 0.551.86 ± 0.52&2.42 ± 0.623.82 ± 0.62***
TC (mmol/l)14.78 ± 2.9611.34 ± 2.21&&15.32 ± 2.8917.11 ± 3.82*
HDL-C (mmol/l)3.44 ± 0.875.12 ± 0.95&&&3.47 ± 0.782.35 ± 0.89*
LDL-C (mmol/l)12.01 ± 1.1210.12 ± 1.08&&11.90 ± 1.3214.78 ± 2.76**
  1. n = 10; AG-NC miR-637 agomir negative control; AG miR-637 agomir, AN-NC miR-637 antagomir negative control, AN miR-637 antagomir, TG Triglyceride, TC Total cholesterol, HDL-C High density lipoprotein cholesterol, LDL-C Low density lipoprotein cholesterol
  2. &, && and &&&& respectively indicate p < 0.05, p < 0.01 and p < 0.001
  3. *, ** and *** respectively indicate p < 0.05, p < 0.01 and p < 0.001