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Fig. 2 | Cellular & Molecular Biology Letters

Fig. 2

From: MicroRNA-429 inhibits neuroblastoma cell proliferation, migration and invasion via the NF-κB pathway

Fig. 2

miR-429 inhibition accelerates the proliferation, migration and invasion of neuroblastoma cells in vitro. a – Downregulation of miR-429 by transfection with miR-429 inhibitor in SH-SY5Y and SK-N-SH cells. b – Colony formation assays were applied to determine the effect of miR-429 knockdown on SH-SY5Y and SK-N-SH cell proliferation ability. c and d– Wound-healing assays and Transwell assays were employed to examine the effect of miR-429 knockdown on the migration capacity of SH-SY5Y and SK-N-SH cells. e – The percentage of apoptotic cells was determined by flow cytometry. Error bars represent the means ± SEM of at least three independent experiments. n.s.: not significant; *p < 0.05 and **p < 0.01 vs. the control group

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