Fig. 6
From: MicroRNA-429 inhibits neuroblastoma cell proliferation, migration and invasion via the NF-κB pathway
miR-429 overexpression inhibited neuroblastoma growth in a nude mouse xenograft model. The mice were randomly assigned to the control or experimental group (five mice per group). Then, 2 × 106 of the NC or miR-429 mimic SH-SY5Y cells subcutaneously injected into the nude mice. a – Tumor volume was calculated twice weekly. b – Photographs of tumors derived from NC and miR-429 mimic cells in nude mice. c – Weights of tumors. d – IKKβ expression was examined in xenografts that were treated with or without miR-429 mimic-transfected cells. Error bars represent the means ± SEM of at least three independent experiments. N.S.: not significant; *p < 0.05 and **p < 0.01 vs. the control group